Eublepharis macularius (Leopard gecko): 129340224
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Entry
129340224 CDS
T09084
Symbol
TOP3A
Name
(RefSeq) DNA topoisomerase 3-alpha isoform X1
KO
K03165
DNA topoisomerase III [EC:
5.6.2.1
]
Organism
emc
Eublepharis macularius (Leopard gecko)
Pathway
emc03440
Homologous recombination
emc03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
emc00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
129340224 (TOP3A)
03460 Fanconi anemia pathway
129340224 (TOP3A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
emc03032
]
129340224 (TOP3A)
03400 DNA repair and recombination proteins [BR:
emc03400
]
129340224 (TOP3A)
Enzymes [BR:
emc01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
129340224 (TOP3A)
DNA replication proteins [BR:
emc03032
]
Eukaryotic type
DNA Topoisomerases
129340224 (TOP3A)
DNA repair and recombination proteins [BR:
emc03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
Bloom's syndrome complex (BTR)
129340224 (TOP3A)
FA (Fanconi anemia) pathway
129340224 (TOP3A)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Topoisom_bac
Zn_ribbon_GRF
Toprim
Zn_ribbon_Top1
Zn_ribbon_GRF_2
zf-C2H2_10
Motif
Other DBs
NCBI-GeneID:
129340224
NCBI-ProteinID:
XP_054850853
UniProt:
A0AA97K692
LinkDB
All DBs
Position
12:complement(27017249..27037133)
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AA seq
1006 aa
AA seq
DB search
MILWTRQFAHCGVRWFFRSRSLCFSQAAEGMMFRNVHKVLCVAEKNDAARGIADILSNGR
MRRREGISKFNKIYEYQYHMFGQNVSVVMTSVSGHLLAHDFKMPFKKWHSCNPLLLFDAE
IEKYCPENYIDIKRTLEREVQHCQALVIWTDCDREGENIGFEVIHVCKAVKPSLQVFRAR
FSEITPRAIRSACENLVQPNQNISNAVDVRQELDLRIGASFTRFQTLRLQKIFPDVLAEQ
LISYGSCQFPTLGFVVERFKAIQAFVPETFYKIKVTHDHEDGTVDFNWKRNRLFNHTACL
ILYQICMEDPLATVVEVGSRPKSKWRPLPLDTVELEKLASRKLKINAKETMKIAEKLYTQ
GYISYPRTETNIFPKDINLPNLVQLQTQDPHWGAFAQRVLDQGGPTPRNGTKSDQAHPPI
HPTKYAGNLQGNEQRLYEFIVRHFLACCSQDAKGQETTVEIDIASERFIAHGLMILARNY
LEVYPYEKWSDKVIPVYEKGSRFQPSTVEMVDGETSPPQLLTEADLISLMEKHGIGTDAT
HAEHIETIKSRMYVGLTPEQRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICE
GKKDKSVVLREQIQKYKQIFVEAVEKANKLDEALSQYFGEVTRVAQEEEIYPAMPDPVRK
CPQCHSDMVLKTKKNGGFYLSCMGYPTCKSAVWFPDSVLAVSKDDSVCDVCRPHPVHRLK
LKFKRGSLPAIMPLEFVGCIGGCDETLREILDLKYLHGPPRPLQPNNQPANPLQANRSLN
CVSNNQNSFARLPTNIPSGPPASHTKVARNPAPAVVDTDENAVVCNCREEAVLLTVRKEG
PNQGRRFYKCSAGSCNFFLWADQEADDRSNRALGGRGERDWGRSWSDGSYPRGGDNGRDE
GRGATCRCDQPAVTRTVQKEGPNKGRQFHTCSKPREQQCGFFQWTDENVAPAAGFPSSHF
QGRETGSNPKRPSSDSSIRAPTAKRSRTCGICHQPGHTRKTCPQNH
NT seq
3021 nt
NT seq
+upstream
nt +downstream
nt
atgatcctctggaccagacaatttgcccactgtggggtcagatggttcttccgttctcgg
agtctctgtttctctcaggctgctgaaggcatgatgttccggaacgtccataaggtgctc
tgcgtggcagagaagaatgatgctgctcgagggattgcagatatcctttccaatggcagg
atgaggcggagagaagggatttccaaattcaacaagatctatgaatatcaatatcacatg
tttggtcagaacgtctctgtggtaatgacttccgtttcaggacatctcctggctcatgat
ttcaagatgccatttaaaaaatggcatagctgcaacccacttctcctctttgatgcagaa
attgagaaatactgccctgaaaactacatagacatcaagcgaaccctggaaagagaagtt
cagcactgccaagctctggtgatctggacagactgcgaccgcgaaggagagaacatcggc
tttgaggtcattcacgtctgcaaagcagtgaagccgagtctccaggtgttccgagctcgt
ttctctgagatcacacctcgtgccatcagaagtgcctgtgagaaccttgtccagcccaat
cagaatatcagcaatgccgtggacgttaggcaagagttggacctcaggataggggcttcc
ttcacccgatttcagacactgaggctccagaaaatcttccctgatgttttggcagaacag
ctaatcagctatgggagctgccagttccccacactgggatttgtggtggaaaggtttaaa
gccattcaagcatttgtgcctgagaccttttataaaattaaagtgactcacgatcatgaa
gacggcactgtggacttcaactggaagaggaatcgtctcttcaaccatacggcatgcctt
attctctatcagatatgcatggaggatccactggccacggttgtggaggttgggagcagg
cccaaaagtaaatggagacccttgccactggacactgtggaacttgagaagctggcttct
cgtaagttgaaaataaatgccaaggaaaccatgaagattgctgagaagctctacactcag
gggtacataagctatcctcgaacagagaccaatattttccccaaagacatcaacctcccc
aacttggtgcagcttcagactcaagacccccactggggagcttttgcacaaagggttcta
gaccagggtgggcctactccccggaatggaactaaatcggatcaggcccatccccctatt
catcccacaaaatatgctggtaatttgcaggggaacgagcagcgactgtatgagttcatc
gtgcgtcacttcctggcttgctgttcccaggacgctaaagggcaggaaacgacagtggag
attgacattgccagtgagcgtttcatagctcatggactcatgatcttggccagaaactac
ctggaagtctatccgtatgagaagtggagtgacaaggttatccctgtgtatgagaagggg
tctcgctttcagcccagcactgtggagatggttgacggggagaccagcccgccccagctg
ctcacagaagcggatcttatttccctcatggagaaacacggcatcggaactgacgctacc
cacgccgagcacattgagaccatcaaatcccgcatgtatgtgggtcttactccagagcag
aggtttcttccagggcacctggggatggggctggtagaaggctacgattccatgggttat
gaaatgtccaagcctgacctccgagccgagctagaagcagacttgaagctaatttgcgag
ggaaagaaggacaaatcagttgtgctgagggagcagatccagaaatacaagcaaatcttt
gtcgaagccgtggaaaaggcaaacaagctggacgaggctctttctcagtattttggggaa
gtgacccgtgttgcccaagaagaagaaatctatccagcaatgccagatcctgtcagaaaa
tgtcctcagtgccacagtgacatggtcttgaagaccaagaagaacggcggattttacctt
agctgcatgggctatcctacctgtaaatctgcagtgtggtttcctgactctgtgctggca
gtgagcaaggatgattctgtctgcgatgtgtgcagaccacatcccgttcacaggttgaaa
ctgaagttcaagaggggcagcctccctgctatcatgcccctggagtttgtcggctgtatt
ggaggctgtgatgaaactctgagggaaatcctggatctgaaatatctgcacggcccgccc
agacctttgcagccaaacaaccaaccagctaaccctttgcaagccaatcgctcccttaac
tgtgtgtccaacaatcaaaacagctttgctcgactaccaacaaacataccatcgggccca
ccagcttcccacacaaaggtggcacgaaatccagcccccgccgttgttgatactgatgag
aatgctgtggtgtgcaactgcagggaagaggctgtactgttgacagtccgcaaagaagga
cccaaccaaggcaggcgcttctacaaatgcagtgcgggcagctgcaacttctttctgtgg
gctgaccaagaagcagatgacaggagcaatcgagcacttgggggcagaggggagagggac
tggggacgctcgtggagtgacggctcttacccaagaggaggtgacaatggcagagatgag
ggaagaggagctacctgcaggtgtgaccaaccagccgtcaccaggacggttcagaaagaa
ggtcccaacaaagggcgccagttccatacctgctccaagcccagagagcaacagtgtggt
tttttccagtggactgatgaaaatgtagcaccagcagcaggctttccttcaagccatttc
cagggaagagagacagggagcaatcccaaaaggccaagcagcgactcttccataagggca
cccacggccaagcggtcgaggacctgtgggatctgccaccaacctggccacacaaggaag
acctgtcctcagaatcactga
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