Eublepharis macularius (Leopard gecko): 129340737
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Entry
129340737 CDS
T09084
Symbol
PFAS
Name
(RefSeq) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
emc
Eublepharis macularius (Leopard gecko)
Pathway
emc00230
Purine metabolism
emc01100
Metabolic pathways
Module
emc_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
emc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
129340737 (PFAS)
Enzymes [BR:
emc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
129340737 (PFAS)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-GeneID:
129340737
NCBI-ProteinID:
XP_054851669
UniProt:
A0AA97KA05
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Position
12:71260799..71285503
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AA seq
1338 aa
AA seq
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MVVVHYYQRPSKTENGPSSLLRTARAALGDSVRAVQRELCFNVNWTEQKPPDTKATELLQ
WIFGCPFEHGDIATKTFLSPSPSDLLIEIGPRLNFSTAASTNAVSVCRAAGLETVDRIEC
SRRYLIKCDQRPSSSEEACLIASLHDRMTEQCYPEPISSFSIAVRPEPVFHVDILGEGRA
ALEKANSQLGLAFDSWDLDFYTNLFQKLGRNPTSVECFDLAQSNSEHSRHWFFKGRLVVD
GQEVKESLFESIMKTQEQSNPNNVIKFCDNSSAIQGREILSLWPRDPSRASPFEKRTSTR
HVIFTAETHNFPTGVAPFSGATTGTGGRIRDVQCAGRGAHVIAGTAGYSFGNLHIPGYSL
PWEDASFPYPGNFARPVEVAIGASDGASDYGNKFGEPVLAGFARSFGQRLADGERYEWIK
PIMFSGGIGAMEDAHVLKEAPQPGMDVVKVGGPVYRIGVGGGAASSIQVQGDNASELDFG
AVQRGDAEMEQKMNRVLRGCVESGEDNPICSLHDQGAGGNGNVLKELSEPAGATIYASRF
QLGDPTLSVLEIWGAEYQESNALLLRPRDATFLRRLACRERCPVDFVGRITGDGRIVLVD
DTKVPASDAELKEGQAGGRPTPVNLKLEWVLGKMPRKEFTLKRVKRALQPLDLPRDLSVV
DALQRVLKLPSVASKRYLTNKVDRSVTGLVAQQQCVGPLHTPLADVAVVALSPFEVVGGA
TALGEQPIKGLIDPAAGARLAVAEALTNLVFARVTDLKDVKCSGNWMWAAKLPGEGAALA
NACRAMCSVMGELGVAVDGGKDSLSMAARVGTETVKAPGTLVISAYAVCPDIRSTVTPDL
KCPEGRGTLLHVAVNPDRHRLGGSALAQCFSQLGDVSPDLDSPATLVSCFQVTQELLKDG
LISAGHDVSDGGLLTCMLEMAFAGNCGARIELGAPGVNALEVLFAEEPGLVLEVPGVAAA
DVCQRYQEAGVRCVPVGHSGSRGANAMVRVTVNGQQVLAEKVGMLRAWWEATSFQLERLQ
ANPECVAQEETGLARRTEPTFVMTFNPHEELPLLREIAMPAPRVAVLREEGSNGDREMVA
AFLMAGFQVWDLNMEDLCSGEMSLDSFRGLVFVGGFSYADVLGSAKGWAASVTFNPRAQA
QFQAFHRRRDTFSLGVCNGCQLMALLGWVGAETLDAEAEAGGSIKPGLLLSPNNSGRFES
RFVALNIEESPALMLRGMAGSTLGIWVAHGEGRMRFRSAEILDRMRSARLVPLRYVDDQG
LPTEEYPMNPNGSPLGIAGICSPDGRHLAMMPHPERCILPWQWPWMPSAWRQSLRVSPWL
RMFQNACEWCLRYPEGQP
NT seq
4017 nt
NT seq
+upstream
nt +downstream
nt
atggttgtagtgcattattaccagcggcccagcaagactgagaatggtccaagcagcctt
ctgcgcacagcccgagctgccttgggtgacagcgttcgagccgtacagagggaattgtgc
ttcaacgttaactggacagagcaaaagcccccagacactaaggcgaccgagttgctacag
tggatctttgggtgcccctttgaacacggtgacattgccactaagactttcctcagcccg
tccccttcggatctgctgatagagattggaccccgattgaacttctcaacagcagcttcc
actaatgccgtatcggtgtgtcgggcggctggactggaaacggttgacaggattgagtgc
tctcgtcgctacctcatcaagtgtgaccaacgtccgtcatcgtctgaggaagcctgtctc
atagcttcgttacatgaccggatgactgagcagtgctacccagagcccatcagtagcttc
tctatagccgtccgccctgagccggtgttccatgtcgatatattaggagaagggagagct
gctctggagaaagccaacagccagctgggtctggcctttgactcctgggatttggacttc
tacaccaaccttttccagaaacttggcaggaatcccaccagcgtagagtgctttgacctt
gcccagtcaaacagtgaacacagccggcactggtttttcaaaggtcgcctcgtagtggac
gggcaggaggtcaaagagtccctcttcgagtccatcatgaagacccaagaacagagcaac
cccaacaacgtcatcaagttctgtgacaacagcagcgcaatccagggcagggagattctt
tcgctgtggcccagagacccgtcccgtgccagcccctttgagaagcgtacgtccactcgg
catgtcattttcacagctgagacccacaactttcccactggtgttgctcctttcagcggg
gcaaccactgggacaggcgggcgaatccgggacgtacagtgtgcaggtcgtggggcccat
gtgattgcgggcacagctgggtacagcttcggcaatctccatatcccaggatactcgtta
ccatgggaggatgcatcattcccatatccaggcaacttcgctcggcctgtagaggtggcc
atcggagctagtgacggtgcttccgattacggaaacaaatttggggaacctgtgctagca
ggatttgcacgctcctttgggcagcgtctggcagatggtgagcggtacgagtggatcaaa
cccatcatgttcagcggtggcatcggggccatggaagatgcgcatgtgctcaaggaagcc
ccgcagcctggtatggatgttgtgaaggttggaggccccgtctatcgaattggtgttggg
ggaggagctgcttcctccatccaggtgcagggcgataatgccagcgagctggattttggg
gccgtgcaacgaggggatgctgagatggaacagaagatgaaccgagtgctgcgaggctgt
gtggaaagcggcgaggacaacccgatctgcagtttgcatgaccagggtgctggaggcaat
gggaatgtgctgaaggaactgagtgaaccagccggggccactatctatgcaagccgcttc
cagctgggagatcccacattgagtgtcctggaaatttggggggctgagtaccaagagtcc
aatgcccttctgctccgtcctcgtgatgcgaccttcttgcggcgattggcctgccgtgag
aggtgtcctgttgacttcgtaggccggattacaggcgatggacggatcgtgctggtcgat
gacacgaaggttccggcaagcgatgcggagcttaaggaagggcaagcgggaggaagaccc
acccctgtgaatttgaaactggaatgggtgctggggaagatgccacgcaaggaattcact
ttgaagcgagtgaagcgcgcccttcaacctctggacttgccccgtgaccttagtgtggtg
gatgccctccagcgagtcctgaagctaccgtcggtggctagtaaacgttacctgaccaat
aaggtcgatcggtcggtgacggggttggtggcgcagcagcagtgcgtgggtcccctgcat
acccctctggcagatgttgcagtggtggccctctcgccctttgaggtagtgggaggagcc
acagccctcggagagcagcctatcaaggggctcattgacccagcagccggcgctcgactg
gctgtggcagaagctcttaccaacctggtctttgcccgtgtcactgacctcaaggatgtg
aaatgcagtgggaactggatgtgggcagccaagctccctggtgagggggcagccttggct
aatgcctgtagggcgatgtgctctgtgatgggggaactgggcgtggctgttgacggcggc
aaggactcgctcagcatggcagcccgggtcggcacagaaaccgtcaaggcacctgggacc
ctggttatctcagcttatgctgtctgcccagatatcagatctactgtcacccctgatctt
aaatgtccagaaggcagagggaccctgcttcatgttgcagtcaatccagatcgacatcgc
ctggggggcagcgccctggcccagtgtttctctcagctgggggatgtttccccagacctg
gatagccctgctactcttgtttcttgcttccaagtcacccaagagctgctgaaagatggc
ttgatttctgctgggcacgatgtgagtgacgggggccttctgacgtgcatgctggagatg
gcttttgcagggaattgtggagcccgcatagagctgggtgcccctggagtcaacgccctg
gaggtgctgtttgcagaggaacccggcctggtgctagaggtgcccggcgtagcagcggct
gatgtctgccaacgataccaagaagccggggtgcggtgtgtacctgttgggcattcaggt
tcccggggagccaatgccatggttcgagtcactgtaaatggccagcaagtgctggctgag
aaagtagggatgttacgggcctggtgggaagccaccagcttccagctagagcggctgcaa
gccaaccctgagtgtgtggcccaagaagagaccgggctggccaggcgcacagaaccaacc
tttgtcatgacctttaacccccatgaagagcttcccctgctacgggaaatagccatgcct
gccccccgtgttgctgtgcttcgggaggaagggagtaacggggaccgtgaaatggtggct
gctttccttatggctggttttcaggtctgggacctcaacatggaagacctgtgctcgggc
gagatgtctctggactccttccgaggcctggtgttcgtcggagggttcagctatgcggat
gtcttgggctctgccaaaggctgggcggcttccgtgacctttaacccccgagcgcaggct
cagttccaggcattccaccgtcgcagagataccttcagcctgggcgtgtgcaacggctgc
cagctgatggcgttgcttgggtgggtgggggcagaaaccctggatgccgaagctgaagca
ggtggctcaatcaaacctgggctgttgctgagccccaacaattctgggcgctttgaatca
cgttttgtggctctgaacatcgaggaaagtccagcgctgatgctgcggggtatggctggt
tccaccctgggcatctgggtggcacatggagaaggtcggatgcggttccgctcagccgaa
atcctggatcgcatgcgctctgcccgtctggtcccactgcgctacgtggatgaccagggg
ctgccaacggaggagtatcctatgaatcctaatggctctccactaggtattgccggcatt
tgttctcctgatggacgccacttggccatgatgcctcatcccgagcgctgcatcctgcct
tggcagtggccctggatgccaagcgcttggcgccagtctctgcgggtctccccatggctg
cgcatgttccagaatgcctgtgaatggtgcttgcgttatcctgaaggccagccttga
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