Eublepharis macularius (Leopard gecko): 129343968
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Entry
129343968 CDS
T09084
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
emc
Eublepharis macularius (Leopard gecko)
Pathway
emc00562
Inositol phosphate metabolism
emc01100
Metabolic pathways
emc04012
ErbB signaling pathway
emc04020
Calcium signaling pathway
emc04070
Phosphatidylinositol signaling system
emc04370
VEGF signaling pathway
emc04625
C-type lectin receptor signaling pathway
Module
emc_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
emc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
129343968 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
129343968 (PLCG2)
04370 VEGF signaling pathway
129343968 (PLCG2)
04020 Calcium signaling pathway
129343968 (PLCG2)
04070 Phosphatidylinositol signaling system
129343968 (PLCG2)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
129343968 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
emc04131
]
129343968 (PLCG2)
Enzymes [BR:
emc01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
129343968 (PLCG2)
Membrane trafficking [BR:
emc04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
129343968 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
129343968 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
C2
SH3_1
SH3_9
SH2_1
SH3_2
PH_12
EF-hand_PLCG1
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
129343968
NCBI-ProteinID:
XP_054856384
UniProt:
A0AA97LI87
LinkDB
All DBs
Position
16:complement(22379730..22465719)
Genome browser
AA seq
1263 aa
AA seq
DB search
MSKKSNDYGVLPEYEKSQIKRTLELGTVMTVYSLKKSSPERRTIQVIMETRQVAWSKTAD
KIEGFLDLMEIKEIRPGKNSKDFERGKASRQKDDVCFTVFYGTQFVLSTLSLAADSKEDA
DKWLCGLHILHQDAMKASTLAITESWLRKQIYSVDQSRRNSISLRELKTVLPLVNFKVTN
MKFLKDKFAEIKAVKEELSFEQFHLFYKKIMFEQQKMILDEFKKDSTMFLLGNTDRPDAS
AVHLHDFQRFLLHEQQESWAQDLNKVRERMSKFIDDTMRETNEPFLYVDEFLTYLFSKEN
SIWDEKYDSMDLQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELD
CWDGPDGKPIIYHGWTRTTKIKFDDVVQAIKEHAFVTSEFPVILSIEEHCSVEQQRYMSK
VFKEVFGDQLLTKPIEASADQLPSPTQLKEKFIIKHKKLGPKGDVDVNTEDKKEEKKQQG
ELNMWDTIEQKWTRHYCAIADEKLSFSDDIEQNAEEEPLKEVKRTELHCTEKWFHGKMKE
GRKTAEKLLQEYCAEMGGKDGTFLVRESETLPNGYALSFWRSGRVQHCHIHSLIDGDTVK
YYLTDNLTFDSIYDLVQHYREAHLRCAEFELRLTDAVPNPKPHESEPWYYSNLSRGEAED
MLMRIPRDGAFLIRKREESNSYAMTFRAEGKVKHCRIMQEGRLFVLGTSAYFESLVELVN
YYEKHPLYRKMKLRYPVTEELLDRYSMEKDPSSLYDVKMYVEPTEITPSVPQRTVKALYD
YQAKRPDELTFCRGALIHNVTKESGGWWKGDYGEKVQYYFPANYVEDMSSEKGDELENQI
IEDNPLGSLCRGILDLTIYNVAKMPLGKYGKAFVFVLEPKNPEDPPIEFATEKVEELFEW
YQSIREITWRPVEEENEKRYWEKNQLIAIELSDLVIYCKPTSKTKDNLENPDFKEIRSFV
ETKAENITKQKPVDLLKYNQKGLTRIYPKGQRVDSSNYDPFRFWFCGSQMVALNFQTPDK
YMQMNHALFSLNGRTGFVLQPECMRTEGYDPMPNETKKKLQMILTVRVIGARHLPKPGRS
IACPFVEVEICGAEYDNNKFKTTVVNDNGLNPVWAFQEQVKFEIYDSSLAFLRFVVYEED
MFSDPNFLAHATFPIKGIKSGFRSVPLKNGYSENIELASLLVYCEVQQLLEGEEAIYSSF
RQLRQRQAELNNQLYATRWNMRNSNRDALLREFSVNEGQLQLYQETCNKRLREKRVSNSK
FYS
NT seq
3792 nt
NT seq
+upstream
nt +downstream
nt
atgtccaagaaaagcaatgactatggagtgctgccggaatacgagaagagtcaaatcaaa
aggactctggagctgggcaccgtcatgacagtgtacagcctcaagaagagcagtccagaa
agaaggacaatccaagtcataatggaaaccaggcaggtagcctggagtaagacagctgac
aagatagaaggattcttggatttgatggaaataaaagaaattcggccaggaaaaaattca
aaggattttgaacggggaaaggcatctcgtcagaaagatgatgtttgtttcactgtattc
tatggaactcagtttgttctcagcaccttaagcttagcagctgactcaaaggaggatgct
gacaaatggctgtgtggcttgcatatcttgcaccaggatgctatgaaggcttccaccctt
gcaattacagaaagctggctgaggaagcagatatattccgtcgatcaatcaagaaggaac
agcatcagccttagggaattgaagaccgtgcttcctttagtaaacttcaaggtaaccaac
atgaagttcttgaaggataagtttgcagaaataaaagctgtgaaagaagaacttagcttt
gagcagttccatctgttctataagaagattatgtttgagcaacagaaaatgattcttgat
gaattcaagaaggattccactatgttccttctaggaaacacagatcgccctgatgcttca
gcagtacatttgcatgacttccagagatttttgctacatgagcagcaggaatcttgggca
caggacctgaataaagtaagagaacggatgtcgaaatttatagacgacactatgagagaa
acaaacgaacctttcctttatgttgatgagtttcttacataccttttttcaaaagaaaat
agtatctgggatgaaaagtatgattcaatggatcttcaggatatgaataaccctttgtct
cactattggatttcttcttcacataatacatatctcacaggagatcagcttcgtagtgaa
tcttcaccagaagcttatatcaggtgccttcgaatgggatgccggtgtattgagttggac
tgctgggatggccccgacgggaaacccatcatttatcacggatggacacggacaacgaaa
attaaatttgatgatgttgtgcaggcaatcaaggagcatgcatttgtaacatctgagttc
ccggtgattctgtccattgaggagcattgcagtgtagagcagcagcgctacatgtccaaa
gtgttcaaggaggtgtttggggaccagcttctcaccaagcctatcgaagctagcgctgat
cagctgccgtccccgactcagctgaaagaaaagttcatcatcaagcataaaaaattggga
cccaagggtgatgtagatgtgaacacagaagacaagaaggaggaaaaaaagcaacaagga
gagctcaacatgtgggatactatagaacagaaatggactcgtcattattgcgccatagct
gatgaaaaactttcattcagtgatgatatagaacagaatgctgaagaagaaccattaaag
gaagtgaagcgtacggagctccactgtactgagaaatggtttcatgggaaaatgaaggaa
ggcagaaaaacagctgaaaagcttctgcaggaatattgtgctgaaatgggtggcaaggat
gggacgttcttggttagggagagtgaaactttaccgaatggctacgctctctcattctgg
cgatcaggtagagtccagcactgccacatccattctttgattgatggagatactgtaaag
tattacctgactgacaacctcacctttgatagcatctatgatctagtccagcattacaga
gaagcacatttgcgatgtgctgagtttgagctacgtctgactgatgctgtgcctaacccc
aagccccatgaatcagagccgtggtactacagtaacctgagccgaggggaagctgaagat
atgttgatgcgaattcctcgggatggagcctttttgataaggaagagagaggaatccaat
tcatatgctatgactttcagagccgaggggaaagtaaagcactgccgaatcatgcaggaa
ggccgcctctttgtcctgggcacatctgcttactttgaaagtttagtggagttggtgaac
tactatgaaaagcacccgttgtacaggaaaatgaaattgcgctatcctgtgacagaggag
ttgctggaccgctacagcatggaaaaagatcctagttcgttatatgatgtcaagatgtat
gtggagcccactgaaataacaccttctgtgcctcagagaactgtcaaagccttgtatgat
taccaagctaaaagacctgacgagctgacattttgcagaggggccttaatacataacgtc
acaaaagaaagtggaggctggtggaagggagattatggagaaaaagttcagtactatttt
ccagccaattatgtcgaggacatgtcatctgagaagggtgatgaacttgaaaaccagatt
attgaggacaatcctttagggagtttgtgccggggcattttggatctcaccatatacaac
gtcgcgaaaatgccgctcggaaaatacggtaaggcttttgtcttcgtcctggaacccaag
aatcctgaggatcctcctattgagtttgccacagagaaagtggaagagttgtttgaatgg
tatcaaagcattagagaaatcacatggagaccggtagaagaggaaaatgagaaaaggtac
tgggaaaagaaccagttaattgccatagaattatctgatttggtaatctactgcaaacca
acaagcaaaaccaaggacaatttagaaaatcctgatttcaaggaaattcgttcctttgtg
gaaaccaaggcagaaaacataaccaagcagaaacctgttgatttactcaaatacaaccag
aaaggactgacgcggatatatccaaaagggcagagagtggactcctccaattatgatcct
ttccgcttctggttttgtggctcacagatggtagctcttaattttcaaacaccagataaa
tacatgcaaatgaaccatgccttgttttcacttaatggtcggaccggttttgtactccag
ccagaatgcatgaggactgaagggtatgacccaatgcccaacgaaactaagaagaaacta
cagatgattttgactgtgagggtcatcggtgctcgccatcttcctaagcctggtaggagt
attgcctgcccttttgtagaagtggagatttgtggggctgaatacgacaacaataaattc
aagacaactgttgtgaatgacaacggcctgaacccagtttgggcatttcaggaacaggtg
aagtttgaaatttacgactccagcttagcatttctgcgcttcgtggtgtacgaggaggac
atgttcagcgatccaaatttcttagcccatgccactttccctataaaaggaatcaaatct
ggttttcggtcagtccctcttaagaacggatacagtgagaacatagaactggcttcactc
ctggtgtattgtgaggtgcagcaactgctggaaggtgaagaagcaatctattcatcattc
cggcagttgcggcagcgccaagctgaactgaacaatcagttgtatgccacacgttggaat
atgaggaattctaaccgagatgctttgctgagagagttcagtgtgaatgagggtcagcta
cagttgtatcaagagacatgcaacaagaggttgcgggagaaaagggtcagtaacagcaaa
ttttactcctag
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