Eublepharis macularius (Leopard gecko): 129346015
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Entry
129346015 CDS
T09084
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
emc
Eublepharis macularius (Leopard gecko)
Pathway
emc04217
Necroptosis
emc04620
Toll-like receptor signaling pathway
emc04621
NOD-like receptor signaling pathway
emc05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
emc00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
129346015 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
129346015 (TYK2)
04621 NOD-like receptor signaling pathway
129346015 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
129346015 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
emc01001
]
129346015 (TYK2)
Enzymes [BR:
emc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
129346015 (TYK2)
Protein kinases [BR:
emc01001
]
Non-receptor tyrosine kinases
JAK family [OT]
129346015 (TYK2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
FERM_F1
SH2_1
Kinase-like
Kdo
FERM_C_FAK1
ABC1
FERM_M
RIO1
DUF1340
RNF34L-like_3rd
Motif
Other DBs
NCBI-GeneID:
129346015
NCBI-ProteinID:
XP_054859238
UniProt:
A0AA97KLA7
LinkDB
All DBs
Position
19:22140942..22196611
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AA seq
1187 aa
AA seq
DB search
MPLCHCAVKHSESDMEGCHFSPAGGLRVYLHWKGAEEEEQYQIYTQGTPCAEEICIDIAQ
KIGITPICYSLFALYDPQAKLWFPPNHVFKISSGIKLTLHFRMRYYFRNWHGMNDKEPAV
CRSIPRPNDLEDRSQRGEQGSALLDKSSFEYLFEQGKYDFINDVASLKDLHTEQEIHQFK
NESLGMAVLHLCHIALRKGISLEEVAERTSFKECIPRSFCRQIQQNNYLTKFRLRNIFKK
FLQRFQRHTMSTGKLTEQDIMYKYLVTLENLAPRFGSELFPVLSLETISEGEKVPLYING
GHTPLENSPDSPGSNRPATHEVTITGTEGIQWRLISAERVESHPHKGYLGRKAKTKDHKP
NWSYQPVEKSEPKWVRFCDFQEITHIVVKDCKVSIHRQDNKCLDLTLQSHEAALSLVSLV
DGYFRLTADSSHYLCHEVAPPRLVMSILNGIHGPLQEDFILTKLKREEQEDGLYALRWSV
LDFNRMILSVVRRGQSFRIQDATNYRQFRIQKKGISFVLEGWEQTFSSVQELMNALKGCT
LRSGNETFVLKRCCLPKPGEISDLLITRKVKDSTRQILNLTQLSFHQIRKDEITQRAHLG
QGTRTNIYDGVLRVCGGTSGDDETEYFSTEQNNNSREMRVVLKMLDPSHRDIALAFFETA
SLMSQVSHIHLAFVHGVCVRGSENIMVEEYIEHGPLDVFLRNNKGRITVGWKFTVAAQLA
SALSYLEDKNLVHGNVCAKNILLARKGLEDGLMPFIKLSDPGVSFTVLSREERVDRIPWI
APECVKDVSSLSTAADKWSFGTTLLEICFDADVPLKERTPSEKERFYEKKHRLPEPSFKE
LATLISQCLNYAPGERPSFRTILRDLTQLQPNNLLDISSVNPESPVSDPTVFQKRYLKKI
RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKSLKSGCSQQLLTSWKKEIEILKTLYHENIV
KYKGCCSEQGEKIVQLIMEYVPLGSLRDYLPKHHVSLAHILLFAQQICEGMAYLHSLRYI
HRDLAARNVLLENENVVKIGDFGLAKAIPEGHEYYRVCEDGDSPVFWYAVECLKECKFYY
ASDVWSFGVTLYELLTHCDSSQSPPAKFIEMIGVTQGQMTVLRLIELLDRGRRLPSPKDC
PCEIYRLMKNCWETEASFRPAFTNLVPILKAFHEKYRAQAPSVFSVC
NT seq
3564 nt
NT seq
+upstream
nt +downstream
nt
atgccactgtgccactgtgcagtgaagcacagtgagtcagacatggaagggtgccatttt
tcaccagctggaggactgcgggtgtatctccattggaagggtgcggaagaagaggaacag
tatcagatttacactcaggggactccgtgtgcagaagagatctgcattgatattgcacag
aaaattgggatcacccctatctgctacagtctgtttgctctctatgatccacaagccaaa
ctgtggtttcctcccaaccatgtttttaaaatcagcagtggaatcaagttgaccttgcat
tttcgcatgagatactatttccgaaactggcatgggatgaatgataaggagccagctgtc
tgtcgcagcattcctcgcccaaatgacttggaagacaggtcacagaggggagaacaaggc
agtgccctgctagataaatcgtcctttgagtatctctttgagcaaggaaagtatgacttc
attaacgatgttgcctccctaaaagaccttcacaccgagcaggaaatccaccagtttaaa
aacgagagcctggggatggctgtcctccatctctgtcacattgctctcaggaaaggcatc
tccctcgaagaagtggcagagagaaccagcttcaaagagtgcatcccacgctccttctgc
cggcagattcagcagaacaactacctgaccaagttccgcctgaggaatatcttcaaaaag
ttcctgcagcgcttccagcgccacacgatgagcaccggcaagctgactgagcaggacatc
atgtacaagtatctggtgaccttggagaacctggcccctcggtttgggagcgagctgttc
ccagtcctctcgctagaaaccatttcagaaggtgagaaggtgccactctacatcaatggt
gggcacacgcctctggagaactctcccgattctcctggcagcaacaggcctgccacccat
gaggtcacaatcacgggcaccgaaggcattcagtggcggctgatctctgcggagagagta
gaaagccatccacacaagggttatttggggaggaaagccaagactaaggaccacaaaccc
aactggtcctaccagccggtggaaaaatctgaacccaagtgggtacgcttctgtgacttc
caggagattacacacattgttgtcaaggactgcaaagttagcatccaccgtcaagacaat
aagtgtctggatctgactcttcagtcccatgaggctgctctctccttggtttccctggta
gatggttacttcagactaacggcagattctagtcactatttgtgccacgaagtagctccg
ccacggctggtgatgagcatcctgaatggtatccatggacccttgcaggaagactttatc
ctgactaaactgaagcgggaggagcaggaggacggtctgtatgcccttcgctggagcgtc
cttgacttcaatagaatgatcttgtctgttgtgaggagaggccagagcttccggatacaa
gatgccacaaactacagacagttccggatccagaagaaaggaatttcgtttgtgctggaa
ggctgggagcagacgttttctagtgttcaggaactgatgaatgctctcaaaggctgcact
ttaagatctggaaatgagacctttgttttgaagaggtgttgtctcccaaagccaggagaa
atctcggacttgctgatcacgcggaaagtgaaagatagcacccgtcagattctgaacttg
acccagctaagcttccaccaaattagaaaggatgagatcacccagagagcccacttggga
caagggacacgcaccaacatctacgatggtgttctgcgcgtgtgtggtggcaccagcggt
gacgatgagacagagtacttctccactgagcagaacaacaacagccgggagatgcgcgtg
gtactcaaaatgctggatcccagccacagggacatcgccctggcattctttgagactgct
agcctgatgagccaggtttctcacatccacttggcctttgtgcatggagtttgtgtacgg
ggctcagagaatataatggtggaagagtacattgaacatggccccctggatgtcttcttg
cggaacaacaaagggcgaataacagtgggctggaagttcactgttgctgcacagttagca
agtgccctgagttacttggaagacaaaaatctggtgcatggtaacgtctgtgccaaaaac
atccttttggccagaaaaggtttggaagatggcttgatgccctttattaagctcagcgac
cctggagtcagtttcactgttctctcccgagaagagcgagttgacaggattccatggatt
gctcctgagtgcgtcaaagatgtaagcagcctcagcactgcagctgacaagtggagcttc
ggtaccacgctgctggagatatgttttgatgcggatgtgcctctgaaagaacgcactcct
tccgagaaagagcgtttctatgagaagaaacaccgcctcccagagccctctttcaaagag
ctagctacgttgatcagccagtgcctcaactatgcccctggggagcggccttccttccga
accatcctgcgagaccttacccagttgcagccaaacaacctccttgacatctcttctgtc
aaccctgaatctcccgtctctgatcctactgtctttcagaagcgatatttgaagaaaatc
cgagatctgggtgagggacactttggcaaagtgagcctgtattgctacgatcctaccaat
gacggcacaggcgagatggtggctgtgaagtccttgaaatcgggctgtagccagcagctc
ttgaccagctggaaaaaagaaattgagatcctgaagacgctctaccatgaaaatattgtc
aaatacaagggttgctgcagcgagcaaggggaaaagattgtacagctcatcatggagtat
gtacctttgggaagcctgagagattaccttccgaagcaccacgtcagcctggctcacatt
ctcctctttgcccagcagatctgtgagggaatggcttacctgcactccctgcgctacatc
cacagggatctggcagccaggaatgtgctcctggagaatgagaacgtggtgaagattggg
gactttggccttgccaaagccatcccagaagggcatgaatactaccgtgtttgtgaagat
ggagacagccctgtcttttggtatgctgtggagtgcctgaaggagtgtaaattttactac
gcctctgatgtctggtcctttggggttaccctgtatgaactcttgacacactgtgattct
agtcagagccccccagcgaaattcattgagatgattggagtaactcagggccaaatgact
gtactgagacttatagaactgctggacagagggaggaggctccccagccccaaggactgt
ccttgtgagatttaccgcctgatgaaaaattgttgggaaacggaagcttccttccgccca
gccttcaccaacctcgtgcccatcctcaaagccttccatgagaagtacagggcccaggcc
ccctcggtcttcagtgtctgttga
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