Eublepharis macularius (Leopard gecko): 129346186
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Entry
129346186 CDS
T09084
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
emc
Eublepharis macularius (Leopard gecko)
Pathway
emc04140
Autophagy - animal
emc04141
Protein processing in endoplasmic reticulum
emc04210
Apoptosis
Brite
KEGG Orthology (KO) [BR:
emc00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
129346186 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
129346186 (ERN1)
09143 Cell growth and death
04210 Apoptosis
129346186 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
emc01001
]
129346186 (ERN1)
Enzymes [BR:
emc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
129346186 (ERN1)
Protein kinases [BR:
emc01001
]
Serine/threonine kinases: Other
IRE family
129346186 (ERN1)
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ
PQQ_2
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
129346186
NCBI-ProteinID:
XP_054859470
UniProt:
A0AA97KNX3
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Position
19:complement(2251414..2309228)
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AA seq
979 aa
AA seq
DB search
MAWGGRGARPRPASLGLLWLLLLLGGPSCGNAGSVTLPETLLFVSTLDGNLHAVSKRTGS
IKWTLKEDPVLQVPLHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRS
TDGILYMGKKQDSWYVIDLMTGEKQQTLTSSFAESLCPSTSLLYLGRTEYTITMYDTKSK
ELRWNATYFDYAATLPDEDVQYKMSHFASNGDGLVVTVDSESGDVLWIQNYGSPVVAFYI
WQREGLWKVMHTNVGIETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLMPTLYVGKYST
SLYASPSMVHEGVAIMPRGSAIPLIEGPKTRSVTIEDNGECVITPSTDLKFTSGLKHKNR
LNYLRNHWLLIGHHETPLSAPTKILEKFPSNLPKRQENIIPADSDRAAFEEAIDITGSSP
KDLPPPIPEDAEEMLSQPAPRPEAQVDSLLKDMATVILSTFLIVSWVAFIITYPMSVHHQ
QQRQHRQFQKQLEEKIQLLQHQSFNPPIDLPPEADFSDGSCIKAESSATSTPNTSPKASN
HSAYSNVSASDVGSGLSTEQEEDGDIGVITVGKISFHPKDMLGHGAEGTIVYRGTFDNRA
VAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIALELCAATLQEYVEQ
KDFSYHGLQPITVLQQTMSGLAYLHSLNIVHRDLKPHNILISMPNAHGKVKAMISDFGLC
KKLAAGRHSFSRRSGVPGTEGWIAPEILSEDRKENPTHTVDIFSAGCVFYYVVSEGNHPF
GKSLQRQANILLSAYNLDFLNPEKHEDIVARDLVEQMISTDPQKRPSANCVLKHPFFWGL
EKQLQFFQDVSDRIEKEALDGPIVKELERGGRAVVKMDWREHITVPLQTDLRKFRSYKGG
SVRDLLRAMRNKKHHYRELPQEVQETLGTVPDDFVRYFTLRFPHLLLHTYRAMQICSQER
LFQPYYMQDSEHIPPRDAV
NT seq
2940 nt
NT seq
+upstream
nt +downstream
nt
atggcgtggggaggccgcggcgcccggccccggccggcctccctcgggctgctgtggctg
ctgctcctgctgggcggcccgagctgtgggaatgccggttcagtgactcttccagagaca
ctactgtttgtttcaactctggatgggaacttgcatgccgtgagcaagaggacggggtca
attaagtggactttaaaagaagatcctgtacttcaggtgccattacatgtagaagaaccc
gcatttcttcccgaccctaatgatggtagtctgtacactcttggcggcaagaataacgaa
ggcttgaccaaactaccattcaccattcctgaactggtccaagcatccccttgccgcagt
acagatggcatcctatacatgggaaagaagcaggacagctggtacgtgatagacctcatg
acgggagagaaacagcaaactctgacctcttcatttgccgaaagcctttgcccgtctacg
tctctcctctaccttggccgaacagaatacacaataacgatgtacgataccaagagtaaa
gagctccgatggaacgctacctactttgattatgccgctacgttgcctgatgaagacgtg
caatacaaaatgtcccattttgcatctaatggagatgggctggtggtgacggtggacagt
gagtctggggacgtcctgtggatacagaattacggctcccccgttgtagctttttatatc
tggcagcgggaggggttgtggaaagtcatgcacaccaatgtgggaatagaaacgctgcgg
tacctgacattcatgtctggtgaagttggacgcatcactaagtggaaatacccctttcct
aaagaaacagaggccaagagcaaattgatgccaacgctctacgtggggaaatattccacc
agcttgtatgcatcgccatcaatggttcacgaaggagtggctattatgccccggggaagc
gcaataccattgatagagggtccaaaaacacgcagtgtcacgattgaagacaacggagag
tgtgttatcacccccagtactgatctgaagtttacttctggattgaaacacaagaacaga
ctcaactatttgcggaatcattggcttctaatagggcatcatgagacaccgctgtcagcc
ccaacaaagatcctggagaaatttccaagcaatttgcctaagcggcaagaaaatattatc
ccagcggattcggacagagctgcttttgaagaggccattgatattactgggagttcccca
aaggacttgccccctcccatcccagaggacgctgaagagatgctcagccaacctgcccct
cgaccggaagctcaagtggactccctgttgaaggacatggccaccgtcatcctcagcacg
ttcttaattgttagctgggtcgcctttatcatcacgtatccaatgagcgttcaccatcag
cagcaacgacaacaccgacagtttcagaaacagctggaggaaaagatccagttgttgcag
caccagtccttcaacccgcccatcgacttgcccccggaggctgacttctcagatggttcc
tgcataaaggcagaaagctcagccaccagcaccccaaacacgtccccgaaggcgtcaaat
cactctgcctattccaatgtttctgcctctgacgttgggagcggcctgtcaacggaacag
gaagaagatggagacatcggtgtcataaccgttggaaagatctcattccacccgaaggac
atgctcggacatggagccgagggaacaattgtttatagggggacgtttgataaccgagca
gtcgctgtgaagagaattctcccggaatgcttcagctttgctgatcgagaggtgcagctg
ctgcgagaatctgacgaacatccaaacgtgatccgctacttctgcacagagagggatcgc
cagttccagtacatagcccttgagctctgcgctgccactttacaggagtatgtggaacaa
aaggacttcagttaccacggtttgcagcctatcaccgttttacaacagacaatgtccggt
ctcgcttatctccactctctcaatattgtccacagagacctgaagccccacaatatcctc
atttctatgcctaatgcccatgggaaggtcaaagccatgatctcagacttcggcctgtgc
aagaagctcgcagctggcaggcacagtttcagccgtcgatctggagtgccaggcaccgaa
ggctggatcgctccagagatactgagtgaagaccgcaaagagaatccaacacatactgta
gatattttttcagcgggatgcgtcttctattacgtggtatcagaaggcaaccacccattt
ggcaaatccctgcagcggcaagccaatattttgttgagtgcctacaatctggacttccta
aatccagagaagcatgaggacatagttgctcgtgacttagtagagcaaatgataagtaca
gaccctcagaagcggccttcagctaactgcgtgttaaagcacccttttttctggggttta
gagaagcagctccagtttttccaggatgtcagcgaccgaatagaaaaagaagccttagat
ggcccaatcgtgaaggagctggagagaggagggcgggcagtggtgaaaatggactggagg
gagcacatcaccgtccctctacagacagatcttcgaaaattccggtcctataaagggggt
tcagtcagagatcttctgcgagccatgagaaataagaagcaccattatagagaactgccc
caggaagtgcaggagactttgggcactgtcccagatgactttgtgcgttactttactttg
cgtttccctcaccttcttcttcacacctaccgtgctatgcaaatctgctcccaggaaaga
ctatttcagccttattatatgcaggactctgaacacatacctcccagagatgctgtttga
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