Escherichia coli NA114 (UPEC): ECNA114_2630
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Entry
ECNA114_2630 CDS
T01998
Symbol
purL
Name
(GenBank) Phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ena
Escherichia coli NA114 (UPEC)
Pathway
ena00230
Purine metabolism
ena01100
Metabolic pathways
ena01110
Biosynthesis of secondary metabolites
Module
ena_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ena00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
ECNA114_2630 (purL)
Enzymes [BR:
ena01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
ECNA114_2630 (purL)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AEG37465
LinkDB
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Position
complement(2693322..2697209)
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AA seq
1295 aa
AA seq
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MMEILRGSPALSAFRINKLLARFQAARLPVHTIYAEYVHFADLNAPLNDDEHAQLERLLK
YGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGMAYYIEAGTLT
NEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGL
ALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFKM
IKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHETGRYDFHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI
RADHVQKDEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL
EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDL
PLDVLLGKTPKMTRDVQTLKAKGDALAREGITIADAVKRVLHLPTVAEKTFLVTIGDRSV
TGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEAL
TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS
MKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGA
TALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFA
GHCGIDADIASLGDDRLAALFNEELGAVIQVRAADREAVEAVLAQHGLADCVHYVGQAVS
GDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVK
LSFDINEDVAAPFIATGVRPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRT
GLEGFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQM
MSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGR
VEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPH
PERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattctgcgtggttcgcctgcattgtcggcattccgaatcaacaaactgctg
gcacgttttcaggctgccaggctcccggttcacactatttacgccgagtatgtccatttt
gctgacctcaatgcgccgttaaacgatgatgagcacgcacaacttgaacgcctgctgaaa
tatggcccggcactcgccagccacgccccgcaaggcaaactcctgctggtgaccccgcgt
cctggcaccatctctccctggtcttcgaaagcgaccgatatcgcccataattgcggtcta
caacaggtaaaccgccttgagcgcggcatggcttactatatagaagccggtacgctgacc
aatgaacaatggcagcaggtgaccgctgaactgcacgaccgcatgatggaaacggtcttt
tttgctttagatgatgcagagcagttgtttgcacaccatcaaccgactccggtcaccagc
gtagatttgctggggcagggccgtcaggcgctaatcgacgctaacctgcgtcttggcctg
gcactggcggaagatgaaattgactatctgcaggatgcgttcacaaagctgggtcgtaac
ccgaacgacatcgagctgtatatgttcgcgcaggcgaactccgagcactgccgtcacaaa
atttttaacgccgactggattatcgacggtgaacagcagccgaaatcgctgttcaagatg
atcaaaaacaccttcgaaaccacgccagaccacgttctctctgcttataaagataacgcc
gctgtaatggaaggttctgaagtgggtcgctactttgctgaccacgaaacgggccgctac
gatttccatcaggaaccggcgcatattctgatgaaagttgaaacccacaaccacccgacg
gcgatttctccgtggccgggtgcggcgaccggttctggcggtgaaatccgcgatgaaggt
gccaccgggcgcggcgcaaagccgaaagccggtctggttggtttctccgtatccaacttg
cgtattccgggctttgaacagccgtgggaagaagatttcggtaagcctgagcgcattgtc
accgcgctggacatcatgaccgaaggcccgctgggcggcgcggcgtttaacaacgaattt
ggtcgcccggcactgaacggctacttccgtacttatgaagaaaaagtgaacagccacaat
ggcgaagagctgcgcggttatcacaaaccgatcatgctggcgggtgggatcggcaacatt
cgcgccgatcacgtacaaaaagacgagatcaacgttggtgcgaagctggtcgttctcggc
ggcccggcaatgaacatcggtcttggcggcggcgcggcgtcttccatggcatctggtcag
tctgatgccgacctcgactttgcttccgtacagcgcgacaacccggagatggagcgtcgc
tgccaggaagtgatcgaccgttgctggcagcttggtgatgccaacccaatcctgtttatc
cacgacgttggcgcaggcggtctttctaacgccatgccggaactggtgagcgacggcggg
cgcggcggtaaattcgaactgcgcgatattctgagcgacgagccaggcatgagcccgctg
gaaatctggtgtaacgaatcccaggaacgctacgtgctggcagttgctgccgatcagtta
ccgctgtttgacgaactgtgtaagcgtgaacgcgcaccgtacgcggtgattggtgaagcg
accgaagaactgcatctttctctgcacgatcgtcattttgataatcagccgattgatcta
ccgctggacgtactgcttggcaaaacgccgaagatgacccgcgatgtgcaaacgctgaaa
gcgaaaggcgacgcgctggcccgtgaagggatcaccatcgctgacgcggtgaaacgcgtg
ctgcatctgccgaccgtggcggagaaaactttcctggtgaccatcggtgaccgcagcgta
accggcatggtggcgcgcgatcagatggtggggccgtggcaggtgccggtcgctaactgc
gcggtcactaccgccagcctcgacagctactatggcgaagcgatggcaattggcgaacgt
gcgccagttgcgctgctggatttcgccgcttctgcccgtctggcagtcggtgaagcgcta
accaacatcgccgcaacacaaattggcgatatcaaacgcattaaactttccgccaactgg
atggcggcggcaggccaccctggtgaagatgcgggcctgtatgaagccgttaaagctgtg
ggcgaagaactttgtccggcgctgggcctgacgataccggtgggtaaagactctatgtcg
atgaaaacccgctggcaggaaggtaacgaagagcgcgaaatgacgtcgccgttgtcgctg
gtgatttccgcatttgcccgcgtggaagatgtacgtcacaccattacgccgcagctttct
accgaagataacgcactgttgctgattgatttgggcaaaggcaataacgcgctgggcgca
acggcactggcgcaggtttatcgtcagcttggcgacaaaccggcagatgtacgcgatgtt
gcccaactgaaaggcttctatgacgcgattcaggcgctggttgcacagcgtaagctgctg
gcgtatcacgaccgctctgatggcggcctgctggtaacgctggcggaaatggcctttgct
ggtcattgtggcattgacgcggatatcgcctctctgggtgacgatcgcctggcggcgttg
tttaacgaagaactgggtgcggtgattcaggttcgagctgctgatcgtgaagccgttgaa
gcggtactggcacagcatgggcttgctgattgcgtccattatgttgggcaggcggtttcc
ggtgaccgttttgtgattactgccaacgggcagactgtatttagcgaaagccgcaccacg
ctgcgtgtctggtgggcagaaactacctggcagatgcagcgcctgcgtgacaacccggag
tgtgccgatcaggaacaccaggcgaaatcaaacgacgccgatccgggcctgaatgtgaaa
ctgtcgtttgatatcaacgaagatgtggcagcaccgtttattgccactggcgtgcgcccg
aaagttgccgtgctgcgtgagcagggcgtgaactcgcatgttgaaatggcggcagctttc
caccgtgcaggcttcgatgctatcgacgtgcatatgagcgatctgctggctggacgcacg
ggcctggagggtttccacgccctggtcgcgtgtggtggtttctcctacggtgatgtgctg
ggcgctggtgaaggttgggcgaagtctatcctgttcaatgaccgtgtacgcgatgagttt
gcaaccttcttccatcgtccgcaaacgctggcgctgggggtatgtaacggttgccagatg
atgtctaatctgcgtgaactgatcccgggtagcgagttgtggccacgttttgtgcgtaac
acctccgatcgctttgaagcgcgtttcagtctggtagaagtaacccaaagcccgtcgctg
ctgttgcaggggatggtgggctcgcagatgccgattgctgtgtctcatggtgaagggcgc
gtggaagtgcgtgatgcggcgcatctggcggcactggaaagcaaagggctggtggcactg
cgctatgtcgataacttcggcaaagtcactgaaacctacccggctaacccgaacggttca
ccgaacggtattacggcggtcacgactgaaagtggtcgagtcaccattatgatgccgcac
ccggaacgagttttccgtactgtcagcaactcctggcatccggaaaactggggcgaggat
ggcccatggatgcgcattttccgcaatgcacgtaagcagttggggtaa
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