KEGG   Enterobacter sp. FY-07: AKI40_0959
Entry
AKI40_0959        CDS       T04405                                 
Symbol
cysG1
Name
(GenBank) siroheme synthase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
enf  Enterobacter sp. FY-07
Pathway
enf00860  Porphyrin metabolism
enf01100  Metabolic pathways
enf01110  Biosynthesis of secondary metabolites
enf01120  Microbial metabolism in diverse environments
enf01240  Biosynthesis of cofactors
Module
enf_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
enf_M00924  Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:enf00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    AKI40_0959 (cysG1)
Enzymes [BR:enf01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     AKI40_0959 (cysG1)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     AKI40_0959 (cysG1)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     AKI40_0959 (cysG1)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M 2-Hacid_dh_C Pyr_redox Shikimate_DH GFO_IDH_MocA Exo_endo_phos_PGAP2IP TrkA_N
Other DBs
NCBI-ProteinID: AMO47382
LinkDB
Position
990362..991777
AA seq 471 aa
MDYLPLFAAVKDRPVLVIGGGEIAARKIAFLRRAGAQVKVVAQHLDASLQQLAERQAIHW
VATTFDESQLDSVFLVIAATNDAALNRRVFDAANARHRLVNVVDDQPLCSFIFPSIVDRS
PLLVAISSGGNAPVLARLLREKIEALLPGNLGRMADVAGRWRTRIKAFRRTTDERRRFWE
SAFRGRFASLMAAGDEPAAEKALEAELTQPGSASGEIILVGAGPGDAGLLTLRGLQVIQQ
ADVVFYDHLVSDAVLELTRRDAEKICVGKRAGAHAVAQHETNRMLVDAAREGKTVVRLKG
GDPFIFGRGGEELQAAAEAGIPFQVVPGVTAASGATAYAGIPLTHRDFAQSVTFVTGHYK
ADSTPFDWSLLAQSRQTLAIYMGTMKAAEISTQLIAHGRDNTTPVAVISRGTRTDQHVAT
GTLEQLEELAKAAPMPALLVVGEVVGLHRELAWFRHTTGTDAFDASVINLA
NT seq 1416 nt   +upstreamnt  +downstreamnt
gtggattaccttccgctgtttgctgctgtaaaagaccgccccgttctggtgattggcggt
ggcgaaattgccgcgcgcaaaatcgcttttttgcgtcgtgcaggcgcacaggtaaaggtt
gtggcgcaacacctggatgcgtcgctgcaacagcttgctgaacggcaggctattcactgg
gtggcgacaacctttgacgagtcacaactggacagcgtttttctggtgattgccgccacc
aatgatgccgcgctgaaccgccgggtatttgatgccgccaacgcgcgccaccggctggtc
aatgtggttgatgatcagccgctgtgctcctttattttcccgtcgattgttgatcgttca
ccgctactggtggcgatctcctccggcggtaacgcaccggtattggcgcgcctgttgcgt
gaaaagattgaagcgttgttacccggcaatctggggcgcatggcggacgtcgccgggcgc
tggcgcacacgtattaaagcatttcgtcggaccaccgatgaacgtcgccgtttttgggaa
agcgcctttcgcgggcgttttgccagcctgatggccgcaggtgatgaacccgcagcggag
aaagcgctggaagcggaactgacgcagccgggctcagcgagtggggaaattattctggtc
ggcgcggggccgggcgacgcaggcttgctgacgttgcgcggcttgcaggtgattcagcaa
gccgatgtggtgttttacgatcatctggtcagcgatgcggtgctggagctgacccgccgg
gatgcggaaaaaatttgtgtaggtaaacgcgccggggcacatgcggttgcacaacatgaa
accaatcgcatgctggtggatgccgcccgcgagggcaaaacggtagtgcgcctgaaggga
ggcgatccgtttatttttggtcgcggtggagaagagttacaggccgcagcggaagcgggt
attccttttcaggtggtgccgggcgtgacggctgcatccggtgcgaccgcctatgcgggt
attccactgacacaccgggacttcgcgcagagcgtgacgttcgttaccgggcattataaa
gccgatagcacccccttcgactggtcgctgttggcgcaaagccgccagacgctggctatc
tatatggggacgatgaaggccgcggaaatcagcacgcaactgatcgcccacggtcgtgat
aacactacgccagtggcggtcatctcccgcggtacgcgcacggatcagcatgtggctact
ggcacattagaacaacttgaggaactggcgaaagccgccccaatgcccgccttgttagtg
gtgggcgaggtggttgggcttcatcgcgaactcgcctggttccggcatacgacaggaacg
gacgcgtttgacgcttctgtgattaatctggcttaa

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