Enterobacter sp. AN-K1: LOC22_14085
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Entry
LOC22_14085 CDS
T07994
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
enk
Enterobacter sp. AN-K1
Pathway
enk00260
Glycine, serine and threonine metabolism
enk00261
Monobactam biosynthesis
enk00270
Cysteine and methionine metabolism
enk00300
Lysine biosynthesis
enk01100
Metabolic pathways
enk01110
Biosynthesis of secondary metabolites
enk01120
Microbial metabolism in diverse environments
enk01230
Biosynthesis of amino acids
Module
enk_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
enk_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
enk_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
enk00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
LOC22_14085 (thrA)
00270 Cysteine and methionine metabolism
LOC22_14085 (thrA)
00300 Lysine biosynthesis
LOC22_14085 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
LOC22_14085 (thrA)
Enzymes [BR:
enk01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
LOC22_14085 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
LOC22_14085 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
DUF6247
Motif
Other DBs
NCBI-ProteinID:
UFK51544
LinkDB
All DBs
Position
2942480..2944942
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LPNISDAERIFADLLQGLADAQPGFPLAQLKSTVELEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKLSIAIMAGVLEARGHHVTVIDPVEKLLAVGHYLESTVDIAESTRRIAASKIP
SDHMILMAGFTAGNEKCELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTISPIAQFQIPCLIKNTGNPQAPGTLIGASAD
EDDLPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRNGISVVLITQSSSEYSISF
CVPQGDCLRARRALEEEFYLELKEELLEPLSIQERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVDNDDATTGVRVVHQMLFNTDQVIELFLVGVGGVGGAL
LEQVKRQQEWLKKKHIDLRVCGIANSKALLTNVHGLNLENWQAELEEAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRLAASKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELQRFSGILSGSLSFIFGKLDEGMSLSEATRAA
RELGYTEPDPRDDLSGMDVARKLLILARETGRELELSDIVIEPVLPAEFDDSGDVSAFMA
RLPQLDDAFAARVAKARDEGKVLRYVGNIEEDGVCRVKIAEVDGNDPLYKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagttcggcggtacgtcagtggcaaatgcagaacgttttctgcgtgtt
gccgatatcctggaaagcaacgccaggcaggggcaggttgccaccgtgctctctgccccg
gccaaaatcacgaaccacctggtggcgatgattgaaaaaaccatcggtggtcaggatgca
ctaccgaacatcagcgacgccgagcgtatctttgccgatctgcttcaggggctggccgac
gcccagcctggtttcccgctggcgcagctgaaaagcaccgttgaacttgaatttgcccag
attaaacacgttcttcacggtatcagcctgcttggtcagtgtccggacagcatcaacgcg
gcgctgatttgccggggtgaaaaactctctatcgccatcatggctggcgtgctagaagcg
cgcggtcaccacgtgacggtcatcgatccggttgaaaaactgctggctgtgggccactac
cttgaatccaccgtcgacattgccgagtcgacacgccgtattgcggcgagcaaaatcccg
tctgaccatatgatcctgatggcaggctttaccgccggtaacgagaagtgcgaactggtg
gtgctggggcgtaacggctctgactactccgctgccgtgctggcggcctgtttacgcgca
gactgttgtgagatctggactgacgtcgacggcgtttatacctgcgatccgcgccaggta
ccggacgccaggctgctgaagtcgatgtcgtaccaggaagcgatggagctttcctacttc
ggcgctaaagttcttcacccgcgtaccatctccccgattgcccagttccaaatcccctgc
ctgattaagaataccggtaaccctcaggcgccgggcacgctgattggcgccagcgcggat
gaagatgacctgccggtgaaaggcatttctaacctcaataacatggcgatgttcagcgtc
tccggcccggggatgaagggcatggtcggcatggcggcacgcgtctttgccgctatgtcc
cgcaacgggatctccgtggtgctgatcacgcagtcttcttccgaatacagcatcagcttc
tgcgttccgcagggtgattgcctgcgtgcccgtcgcgcgctggaagaagagttctatctg
gagctgaaagaagagctgctggagccgctctcgattcaggagcgtctggcgattatctct
gtggtcggcgacggcatgcgcaccctgcgcggtatctccgccaaattctttgccgcgctg
gcgcgggccaatattaatatcgtggcgattgcccagggctcatcagagcgttccatttcc
gttgtcgtggataacgatgacgccactaccggcgtgcgcgtggtgcatcagatgctgttc
aacaccgaccaggtgattgagctgttcctggtgggcgtcggtggtgtcggtggcgcgctg
ctggagcaggtgaagcgccagcaggagtggcttaagaagaaacatatcgatttgcgcgtt
tgcggcattgcgaactcgaaagcgttgctgactaacgtccacggtctgaatctggaaaac
tggcaggcggagctggaagaggcgaaagagccatttaacctgggccgcctgatccgcctg
gtgaaagaatatcacctgcttaacccggtgattgttgactgtacctccagccaggcggtg
gccgatcagtacgccgacttcctgcgcgaagggttccacgtggtgacgccaaacaaaaag
gccaacacctcgtcgatggattactatcatcaactgcggctggcggcgagtaagtcgcgc
cgtaagtttctgtatgacaccaacgtgggcgcgggcctgccggtcatcgagaacctgcaa
aacctgctgaacgcgggcgacgaactacagcgtttctccggcatcctctccggctccctg
tcgtttatcttcggcaagctggacgaagggatgagcttgtcggaagccacccgcgccgcg
cgcgagctgggctacaccgagccggatccgcgcgacgacctctccggcatggacgtggcg
cgtaagctgctgatcctggcgcgcgaaactggccgcgagctggagctttcggatatcgtg
attgagccggtgctgccagcagaatttgatgacagcggtgacgtcagcgcctttatggcc
aggttgccgcagcttgacgacgcctttgccgcacgcgttgcgaaagcccgtgatgaaggt
aaggtattgcgctatgttggcaacattgaagaagacggcgtctgccgggtgaagattgcc
gaagtggatggcaacgatccgctgtacaaggtgaaaaacggcgagaacgccctggcgttc
tacagccattattatcagccactgccgctggtgcttcgcggctatggcgcagggaatgat
gtgacggcggcaggcgtgtttgccgatctgctgcgtaccctgtcatggaagttaggagtt
taa
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