Enterobacter cloacae subsp. dissolvens SDM: A3UG_03650
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Entry
A3UG_03650 CDS
T02159
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
enl
Enterobacter cloacae subsp. dissolvens SDM
Pathway
enl00300
Lysine biosynthesis
enl00550
Peptidoglycan biosynthesis
enl01100
Metabolic pathways
enl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
enl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
A3UG_03650 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
A3UG_03650 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
A3UG_03650 (murF)
Enzymes [BR:
enl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
A3UG_03650 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
AFM58477
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Position
795847..797205
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AA seq
452 aa
AA seq
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MISLTLGKAATLLQGTLHGQDVTIDAVTTDTRKVTAGCLFVALKGERFDAHDFAEQAKEN
GAGALLVSRKLAIDLPQLVVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTKEHEFAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLEGVAKAKGEIYTGLPDDGIAIMNADNNDWLNWQSIIGSRKTWRFS
PNAANSDFTATNIHVTSHGTEFTLNTPTGGIEVLLPLPGRHNIANALAAAALSMAVGATH
DAIKTGLANLKAVPGRLFPIQLAENKLLLDDSYNANVGSMTAAVQVLSEMPGYRVMVVGD
MAELGDESEACHTQVGEAAKVAGLDCVLSAGKLSQAISHASGVGEHFADKAALIERLKAL
IAEKQMVTVLVKGSRSAAMEEVVHALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcttaacgctcggcaaggcggcaactctcctgcagggtacgttgcatggtcag
gacgtcaccattgacgccgtgacaacagatacccgcaaagtgaccgccgggtgcctgttt
gtggcgctgaaaggcgaacgttttgacgcccacgattttgctgaacaggcgaaagaaaac
ggtgcaggtgcgctgctggtgagccgcaaactcgctatcgatttgccacagcttgtggtg
aaggatacgcgtctggcctttggtgagctggctgcctgggttcgtcagcaggtcccggct
cgcgttgtcgccctgacggggtcgtcgggtaaaacgtcggtcaaagagatgacggcggcc
atactcagtcagtgcggtaacacactttacaccgcaggcaatctaaataatgacatcggt
gtgccgatgacattacttcgcctcaccaaagagcatgagtttgcggtgattgaattaggg
gcaaatcatcagggcgaaatcgcctggaccgtgagcctgacgcgtccggaggccgcgctg
gtgaataacctggctgctgcacatctggaaggttttggttcactcgaaggcgtggcaaaa
gccaaaggcgagatctataccggcctgccggatgatggtatcgccattatgaatgccgac
aataatgactggctgaactggcagagcattattggctcgcgtaagacgtggcgtttctcg
ccaaatgcggccaacagtgattttaccgcaaccaatatccatgtgacctcgcatggcacg
gaattcacactcaataccccaacggggggcattgaggttctgctgccactgcccgggcgc
cataacatcgccaatgcgctcgctgccgcggcgttgtcgatggctgtaggcgcgacacat
gacgcgataaaaaccggtctggcaaatttaaaagccgtaccggggcgtctgttccccatc
cagcttgcagaaaacaaactgctgctggatgactcctacaacgcgaacgtcggttcgatg
acggcggccgtacaggtgctgtccgaaatgccgggttatcgtgtgatggtcgttggcgat
atggccgagttgggcgatgaaagcgaagcctgtcatacccaggtgggtgaagccgcgaaa
gtggcggggctggattgtgtcctgagcgccggaaaactgagccaggcgattagccatgcc
agcggtgttggcgaacattttgccgataaagccgcactgattgaacgtctgaaggcgttg
attgctgaaaaacaaatggtgactgtgttagtgaaaggttcacgtagtgccgccatggaa
gaggttgtgcacgcattacaggagaacgggacatgttag
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