Euhalothece natronophila: FRE64_07295
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Entry
FRE64_07295 CDS
T06117
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
enn
Euhalothece natronophila
Pathway
enn00300
Lysine biosynthesis
enn00550
Peptidoglycan biosynthesis
enn01100
Metabolic pathways
enn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
enn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
FRE64_07295
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
FRE64_07295
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
FRE64_07295
Enzymes [BR:
enn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
FRE64_07295
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
QDZ39761
UniProt:
A0A5B8NMJ2
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All DBs
Position
1519724..1521076
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AA seq
450 aa
AA seq
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MAIELTLSILANVIKPVQVICPDQEKVSVVTGINTDTRTLQKGEIFIALVGEKFDGHQFI
QKALQSGVSALILNENFLGEVSASVPQFYVKNTLTAYQQIAQWWRQQYTIPVIAITGSVG
KTTTKELIAATLGQYGKVLKTEANYNNEIGVPKTLLGLTSEYDYAVIEMAMRAQGEIAQL
TQIAQPNIGVITNVGTAHIGRLGSREAIAQAKCELLAEMPKTGIAILNQDNQRLMATAST
IWTGKTLTYGLEGGDILGQLVDTDTLQVGNERFPLPLSGTHNASNYLAAITVAKALNLDL
TQLQTEIPVTLPGARSRRYSLPNDILLLDETYNAGLESMIAALNLLKATPGKRHIAVLGT
MKELGSESATLHREVGETVSNLNLDQVFILVDEPETEEIAKAAHPVKSECFQNKTELAQR
LKEILAPRDRVLFKASNSVGLEEVLQAITN
NT seq
1353 nt
NT seq
+upstream
nt +downstream
nt
atggcaatagaacttaccctatctattctagcaaatgttatcaaacccgttcaggtgatc
tgccctgatcaagaaaaagtgtcagtggtaactggaattaacacagatactcgtacccta
caaaaaggggaaatatttattgccttagtgggagaaaaatttgatggccatcaatttatt
caaaaagcattacaaagtggtgttagtgcgctcattcttaatgaaaattttttgggagaa
gtttccgcaagtgtcccccaattttatgtcaaaaataccttaacggcttatcaacaaatt
gctcaatggtggcgacaacaatatacgattcccgttattgcaataacaggatcagtgggt
aaaacaacgacgaaagagctaattgctgcgactttggggcaatacggtaaggtcttaaaa
actgaggcaaattataacaatgaaattggtgttcccaaaaccctattaggattaacttct
gaatatgattatgctgtgattgaaatggcaatgcgtgctcaaggtgaaattgcccaatta
actcagatcgcacagccgaatattggtgtaattactaatgtgggaactgcccatattggt
cgcttaggatcaagagaagcaatcgcgcaggctaaatgtgaactcctagcagaaatgccc
aaaacgggaatagcaatccttaatcaggataaccaacgtttaatggcgacagcaagcaca
atttggacagggaaaaccctcacctatggcttagaagggggagacatccttgggcagtta
gttgatacagacaccttacaagtgggcaatgagagattcccattaccgttatctggaacc
cataatgcttctaattatcttgccgcgatcacagtggcaaaggcgcttaatttggatctg
actcaattgcaaacggaaatccctgttaccctacctggggcgcgatcgcgccgttattct
cttcccaacgatattttactcctcgatgaaacttataatgcggggttagaatccatgatt
gctgccctaaacttattaaaagcaactcccggtaagcgtcatattgctgttttaggcaca
atgaaagaattaggaagtgaatcggctaccctgcatcgagaagtaggagaaaccgtgtca
aacctgaatttagatcaagttttcattctagtagatgaaccggaaacggaagaaatcgcc
aaggcagcgcatccagtcaagagtgaatgtttccaaaataagaccgagttagcccagcga
ttaaaagaaattctagcaccgcgcgatcgcgttctttttaaagcttctaattctgtgggc
ttagaagaggttttacaagcaatcactaattga
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