KEGG   Enterobacter kobei ENHKU01: ECENHK_20600
Entry
ECENHK_20600      CDS       T02315                                 
Symbol
cysG
Name
(GenBank) siroheme synthase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
eno  Enterobacter kobei ENHKU01
Pathway
eno00860  Porphyrin metabolism
eno01100  Metabolic pathways
eno01110  Biosynthesis of secondary metabolites
eno01120  Microbial metabolism in diverse environments
eno01240  Biosynthesis of cofactors
Module
eno_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:eno00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    ECENHK_20600 (cysG)
Enzymes [BR:eno01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     ECENHK_20600 (cysG)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     ECENHK_20600 (cysG)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     ECENHK_20600 (cysG)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M Radical_SAM
Other DBs
NCBI-ProteinID: AFP71951
UniProt: A0A145IFD0
LinkDB
Position
4376662..4378035
AA seq 457 aa
MDHLPIFCQLRHRDCLLVGGGDVAERKARLLLEAGARLTVNALTFTPQFDVWAQEGMLTR
VQGEFDESLLDTCWLTIAATDDDAVNQRVSDACEARRIFCNVVDAPKEASFIMPSIIDRS
PLMIAVSSGGRSPVLARLLREKLEAVLPQHLGQIAHYAGQLRSRVKQTFATVGERRRFWE
KFFVNDRLAQSLANQDTKAVEETTEQLLNEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQ
QADIVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLK
GGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLVTGHL
KTGSELDWHNLAAEKQTLVFYMGLNQAATIQAKLLEHGMEADMPVALVENGTAITQRVVD
GVLTQLGELAQQVESPALIVVGRVVELRDKLNWFSNH
NT seq 1374 nt   +upstreamnt  +downstreamnt
gtggaccacctgccgattttttgtcaattacgccatcgcgactgcctgcttgtaggcggc
ggcgatgtggctgagcgcaaggcgcgcctgctgctggaagcgggggcccgactgaccgtg
aatgctctcacctttaccccgcagtttgacgtctgggcccaggaagggatgctcacgcgg
gtacaaggagagtttgatgaatccctgctggatacctgctggctgaccattgccgcaacg
gatgacgatgccgtgaatcagcgcgtcagcgatgcctgcgaagcgcggcgtatcttctgc
aacgtggtcgatgcgccgaaagaagccagctttatcatgccgtcgattatcgaccgctca
ccgctgatgattgcggtgtcatccggtggacgctcacctgttctcgcccgcctgctgcgg
gaaaaactggaagccgtgctgccgcagcatcttggtcagattgcccactatgccggacaa
cttcgttcccgcgtgaagcaaaccttcgcgaccgtaggggagcgccgtcgcttctgggaa
aagttctttgtgaacgacaggctggcgcagtcgctggcgaaccaggacacaaaagcggtg
gaagagacgaccgaacagttactgaacgaaccgctggatcaccgtggagaagtggtgctg
gtcggcgcgggtcctggcgatgcaggcttactgacgctgaaaggcctgcaacagatccag
caggcggatatcgtggtctacgaccgcctggtctccgatgacatcatgaacctggtgcgt
cgcgacgccgatcgcgtcttcgtcggcaagcgcgcgggctaccactgcgtaccgcaggaa
gagattaaccagatcctgctacgcgaggcgcagaaaggtaagcgcgtggtgcgtctgaaa
ggcggcgatccgtttatctttggtcgcggcggcgaagagctggaaaccctgtgcaacgca
ggtattccgttctccgtggtgccagggattacggcggcgtccggctgctcagcctactcc
ggcatcccgctgacccaccgcgattacgcgcagagcgtgcgtcttgtgacgggccacctc
aaaaccggcagcgaactggactggcataatctggccgctgaaaagcagacgctggtcttc
tacatggggctaaatcaggccgccactattcaggcgaaactgctggagcacggcatggag
gcagatatgcccgttgcgctggtggaaaacggtaccgccattacgcagcgtgtggtcgat
ggtgtgctgactcaactcggcgagctggcgcagcaggttgaaagtccggcattgattgtg
gtgggtcgcgtggttgaattacgcgataagctgaactggttctcgaatcactga

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