Enterobacter sp. DSM 30060: HWQ15_11745
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Entry
HWQ15_11745 CDS
T07983
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
ens
Enterobacter sp. DSM 30060
Pathway
ens00260
Glycine, serine and threonine metabolism
ens00261
Monobactam biosynthesis
ens00270
Cysteine and methionine metabolism
ens00300
Lysine biosynthesis
ens01100
Metabolic pathways
ens01110
Biosynthesis of secondary metabolites
ens01120
Microbial metabolism in diverse environments
ens01230
Biosynthesis of amino acids
Module
ens_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
ens_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
ens_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
ens00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
HWQ15_11745 (thrA)
00270 Cysteine and methionine metabolism
HWQ15_11745 (thrA)
00300 Lysine biosynthesis
HWQ15_11745 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
HWQ15_11745 (thrA)
Enzymes [BR:
ens01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
HWQ15_11745 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
HWQ15_11745 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
DUF6247
Motif
Other DBs
NCBI-ProteinID:
QLA02703
LinkDB
All DBs
Position
2455039..2457501
Genome browser
AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LPNISDAERIFAELLQGLADAQPGFPLAQLKTTVELEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKLSIAIMAGVLEARGHHVTVIDPVEKLLAVGHYLESTVDIAESTRRIAASKIP
SDHMILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTISPIAQFQIPCLIKNTGNPQAPGTLIGASAD
EDDLPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRNGISVVLITQSSSEYSISF
CVPQGDCLRARRALEEEFYLELKEELLEPLSIQERLAVISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVDNDDATTGVRVVHQMLFNTDQVIELFLVGVGGVGGAL
LEQVKRQQEWLKKKHIDLRVCGIANSKALLTNVHGLNLENWQAELEEAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRLAASKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELQRFSGILSGSLSFIFGKLDEGMSLSEATRAA
RELGYTEPDPRDDLSGMDVARKLLILVRETGRELELSDIVIEPVLPAEFDDSGDVSAFMA
RLPQLDDAFAARVAKARDEGKVLRYVGNIEEDGVCRVKIAEVDGNDPLYKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagttcggcggtacatcagtggcaaatgcagagcgttttctgcgtgtt
gccgatatcctggaaagtaacgccaggcaggggcaggttgctaccgtgctctctgccccg
gcaaaaatcacgaaccacctggtggcgatgattgaaaaaaccatcggtggccaggatgca
cttccgaacatcagcgacgccgagcgtatcttcgctgaactgcttcaggggctggcagac
gcccagcctggcttcccgctggcgcagctgaaaaccaccgttgaactcgaatttgcccag
attaaacatgtccttcacggtatcagcctgctgggtcaatgcccggacagcatcaacgcg
gcgctaatttgccggggtgaaaaactctctatcgccatcatggcgggcgtgctggaagcg
cgcggtcaccacgtgacggtcatcgatccggttgaaaaactgctggctgtgggacactac
cttgaatccaccgtcgacattgccgagtcgacacgccgcattgcggcgagcaaaatcccg
tctgaccacatgatcctgatggcaggcttcaccgccggtaacgagaagggcgaactggtg
gtgctggggcgtaacggctctgactactccgctgccgtgctggcggcctgtttacgtgca
gactgttgtgagatctggactgacgttgatggtgtatatacctgtgacccgcgccaggtg
ccggacgccaggctgttgaagtcgatgtcgtaccaggaagcgatggagctttcctacttc
ggcgccaaagtgcttcacccacgtaccatctccccgattgcccagttccagatcccttgc
ctgattaaaaacaccggtaatccgcaggcgccgggtacgctgattggcgccagcgctgat
gaagatgacctgccggtaaaaggcatttcgaaccttaataacatggcgatgttcagcgtc
tctggcccgggtatgaaaggtatggttggcatggcggcacgcgtatttgcggccatgtcc
cgtaacgggatctccgtggtgctgatcacgcagtcttcttccgaatacagcatcagcttc
tgcgtcccgcagggcgattgcctgcgcgcccgtcgcgcgctggaagaagagttctacctg
gagctgaaagaagagctgctggagccgctctcgattcaagagcgtctggccgtgatctcc
gtggtaggcgacggcatgcgcaccctgcgcggaatctccgccaaattctttgccgccctg
gcgcgggccaatatcaatatcgtggcgattgcccagggctcatcagagcgttcaatttcc
gttgtcgtggataacgatgacgccactaccggcgtgcgcgtggtgcatcagatgctgttc
aacaccgaccaggtgattgagctgttcctggtgggcgtcggcggcgtcggcggcgcgctg
ctggagcaggtaaagcgccagcaggagtggcttaagaagaaacatatcgatctgcgcgtc
tgcggaattgcgaactcgaaagcgttgctgactaacgtccacggtctgaacctggaaaac
tggcaggcggaactggaagaggcgaaagagccgttcaacctgggtcgtctgatccgtctg
gtgaaagagtatcacctgcttaacccggtgatcgtcgactgtacctccagccaggctgtg
gccgatcagtacgcggatttcctgcgcgaaggtttccatgtggtgacgccgaacaaaaag
gccaacacctcgtcgatggattactatcaccagctgcgtctggcggcgagcaagtcgcgc
cgcaagtttctgtatgacaccaacgtgggcgcaggcctgccggtcatcgagaacctgcaa
aacctgctgaacgcgggcgacgaactacagcgtttctccggcatcctctccggctccctg
tcgtttatcttcggcaagctggacgaagggatgagcctgtcggaagccacccgcgccgcg
cgcgagctgggctacaccgagccggatccgcgcgacgacctctccggtatggatgtggcg
cgtaagctgctgatcctggtgcgcgaaaccggccgcgagctggagctttcggatatcgtg
attgagccggtgctgccagcagaatttgatgacagcggcgacgtcagcgcttttatggcc
aggttgccgcagcttgacgacgcctttgccgcccgcgttgcgaaagcccgtgatgaaggt
aaggtattgcgctatgttggcaatattgaagaagacggcgtctgccgcgtgaagattgcc
gaagtggatggcaacgatccgctgtacaaggtgaaaaacggcgagaacgccctggcgttc
tacagccattattatcagccactgccgctggtacttcgcggctatggcgcagggaatgat
gtgacggcggcgggcgtgtttgccgatctgctgcgtaccctgtcatggaagttaggagtt
taa
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