Enterobacter sp. DSM 30060: HWQ15_12070
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Entry
HWQ15_12070 CDS
T07983
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ens
Enterobacter sp. DSM 30060
Pathway
ens00300
Lysine biosynthesis
ens00550
Peptidoglycan biosynthesis
ens01100
Metabolic pathways
ens01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ens00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HWQ15_12070 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HWQ15_12070 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HWQ15_12070 (murF)
Enzymes [BR:
ens01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HWQ15_12070 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
ADH_zinc_N
Motif
Other DBs
NCBI-ProteinID:
QLA02766
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Position
2534482..2535840
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AA seq
452 aa
AA seq
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MISITLSQAAAVLQGMLHGQDLTIEAVTTDTRKVTAGCLFVALKGERFDAHDFAQQAKDN
GAGALLVNRKLDIDLPQIVVKDTRLAFGELAAWVRQQVPTRVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTHEHEYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIYTGLPDDGIAIMNADNNDWLNWQSIIGSRKTWRFS
PNAANSDFSATNIHVTSHGTEFTLMTPTGDIDVLLPLPGRHNIANALAAAALSMAVGASH
AAIKTGLANLKAVPGRLFPIQLAENKLLLDDSYNANVGSMTAAVQVLSEMPGYRVMVVGD
MAELGDESEACHVQVGEAAKAAGLDRVLSAGTLSKAISDASEVGEHFADKSALIERLKAL
ITEKQIVTVLVKGSRSAAMEEVVHALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcattacgttaagccaggccgctgcggtattgcaggggatgctgcatggtcag
gatctgaccatcgaggctgtgaccaccgacacccgtaaggtgacggcgggctgcctgttt
gtggcgctgaagggtgaacgttttgacgcccacgattttgcgcagcaggctaaagataac
ggcgcgggtgcgctgctggtcaaccgtaagctcgatatcgatttgccgcagattgtggtg
aaagatacgcgcctggcctttggtgagctggcggcatgggttcgccagcaggtgccaaca
cgcgtcgtggcgctgacgggctcgtcgggcaaaacctccgttaaagagatgacggcggcg
atccttagccagtgcggaaacacgctttatacggcgggcaaccttaataatgacatcggt
gtaccgatgacgctgctgcgcctgacccacgagcatgaatatgcggtgattgagttaggg
gctaaccatcagggcgaaatcgcctggaccgtgagcctgacgcgtccggaagcggcgctg
gtgaataacctggcggcggcacatcttgaaggttttggttcgctggccggtgtggcgaaa
gcgaaaggtgaaatttataccggcctgccggatgacggcatcgccattatgaatgccgat
aacaatgactggctgaactggcagagcatcattggttcacgcaaaacctggcgcttctcc
ccgaatgcggcaaacagtgatttttcggcgaccaacattcatgtgacgtcacacggcacc
gagttcaccctcatgaccccaacgggcgacatcgacgtgctgctgcctctgccgggtcgt
cataacatcgccaatgcgcttgctgcggcagcgctctcaatggcggtaggggcctcacat
gctgcgataaaaactggtctggcaaatttaaaagccgtgccggggcgtctgttcccgatc
cagctggctgaaaacaaactcctgctggatgactcctacaacgctaacgtcggctccatg
acggcggccgtgcaggtcttgtctgagatgccgggctatcgcgtgatggttgttggcgat
atggccgagctgggtgatgaaagcgaagcctgccacgtacaggttggcgaagcggcgaaa
gctgccgggcttgaccgcgtactgagcgcaggcacgctgagcaaggccatttccgatgcc
agtgaagttggcgaacattttgccgataaatctgcactgatcgaacgcctgaaggcattg
attacagaaaaacagattgtgactgttttagttaaaggttcacgtagtgccgccatggaa
gaggttgtgcacgcattacaggagaacgggacatgttag
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