Enterobacter sp. SES19: GXP72_03330
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Entry
GXP72_03330 CDS
T11023
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
ente Enterobacter sp. SES19
Pathway
ente00260
Glycine, serine and threonine metabolism
ente00261
Monobactam biosynthesis
ente00270
Cysteine and methionine metabolism
ente00300
Lysine biosynthesis
ente01100
Metabolic pathways
ente01110
Biosynthesis of secondary metabolites
ente01120
Microbial metabolism in diverse environments
ente01230
Biosynthesis of amino acids
Module
ente_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
ente_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
ente_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
ente00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
GXP72_03330 (thrA)
00270 Cysteine and methionine metabolism
GXP72_03330 (thrA)
00300 Lysine biosynthesis
GXP72_03330 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
GXP72_03330 (thrA)
Enzymes [BR:
ente01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
GXP72_03330 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
GXP72_03330 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
DUF6247
Motif
Other DBs
NCBI-ProteinID:
QIR21498
LinkDB
All DBs
Position
706139..708601
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LPNISDAERIFADLLQGLAEALPGFPHAQLKSFVEQEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKLSIAIMAGVLEARGHSVTVIDPVEKLLAVGHYLESTVDIAESTRRIAASKIP
SDHMILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTISPIAQFQIPCLIKNTGNPQAPGTLIGASTD
EDGLPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRNGISVVLITQSSSEYSISF
CVPQADCLRARRALEEEFYLELKEELLEPLAIQERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVDNDDATTGVRVVHQMLFNTDQVIELFLIGVGGVGGAL
LEQVKRQQEWLKKKHIDLRVCGIANSKALLTNVHGLNLENWQAEMKEAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSNQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRLAASKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELQRFSGILSGSLSFIFGKLDEGMSLSEATRAA
RELGYTEPDPRDDLSGMDVARKLLILARETGRELELSDIVIEPVLPAEFDSSGDVAAFMA
SLPQLDDAFAARVAKARDEGKVLRYVGNIEEDGVCRVKIAEVDGNDPLYKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagttcggcggtacatcagtggcaaatgcagaacgttttctgcgtgtt
gccgatatcctggaaagcaacgccaggcaggggcaggttgcgaccgtgctctctgccccg
gcaaaaatcacgaaccatctggtggcgatgattgaaaaaaccatcggtggccaggatgca
ctcccgaacatcagcgacgcagagcgtatcttcgctgacctgctgcaagggctggcagag
gcgctgcctggcttcccgcacgctcagctgaagtctttcgttgagcaggaattcgcgcaa
atcaaacacgtcctgcacggcatcagccttctcggccagtgtccggacagcatcaacgcg
gcgctgatttgtcgcggtgaaaaactttctatcgccatcatggccggcgtgctggaagcg
cgcggccatagcgtgaccgtgatcgatcccgttgaaaaactgctggcggtgggccactac
ctcgaatccaccgttgatattgccgaatcaacccgccgtatcgccgccagcaaaattccg
tctgaccatatgatcctgatggctggcttcaccgccggtaacgagaagggcgagctggtg
gtgctgggccgtaacggctccgactattccgccgccgtgctggccgcctgtttacgcgcg
gactgttgtgagatctggactgacgtcgacggcgtctatacctgcgacccgcgccaggta
ccggacgccaggctgctgaagtcgatgtcgtaccaggaagcaatggaactttcctacttc
ggcgccaaagtgcttcacccgcgtaccatctccccgattgcccagttccagatcccttgc
ctgattaaaaataccggtaacccgcaggcgccgggtacgctgattggcgcgagcaccgat
gaggacggtctgccggtgaaaggcatctccaacctcaacaacatggcgatgttcagcgtc
tccggtccggggatgaaggggatggtcggcatggcggcgcgcgtgtttgctgccatgtcc
cgcaacggtatctctgttgtgctgatcacccagtcctcttccgaatacagcatcagcttc
tgcgtgccgcaggccgactgcctgcgcgcccgccgcgcgctggaggaagagttctatctg
gagctgaaagaagagctgctggagccgctcgcgattcaggagcgtctggcgatcatctcc
gtggtgggcgacggtatgcgtaccctgcgcggtatctccgccaagttctttgccgcactg
gcgcgcgccaatatcaatatcgtggcgattgcccagggctcgtctgagcgttcaatttct
gttgtcgtggacaacgatgacgcgaccaccggcgtacgcgtggttcaccagatgctgttc
aacaccgatcaggttatcgagctgttcctgattggcgtcggcggcgtcggcggcgcgctg
ctggagcaggttaagcgtcagcaggaatggctgaagaagaaacacatcgacctgcgcgtc
tgcgggattgcgaattccaaagcgctgctgaccaacgtccacggcctgaacctggaaaac
tggcaggccgagatgaaggaggcaaaagagccgttcaacctgggccgcctgatccgtctg
gtaaaagagtatcacctgcttaacccggtcatcgtcgactgtacctcgaaccaggcggtg
gccgatcagtacgcggatttcctgcgcgaaggtttccacgtggtgacgccgaacaaaaag
gccaacacctcgtcgatggattactatcaccagctgcgtctggcggcgagcaagtcgcgc
cgcaagttcctgtacgacactaacgttggggcaggcctgccggttatcgagaacctgcag
aacctgcttaacgcgggcgacgaactgcagcgtttctccggcattctctccggctcgctg
tcgtttatcttcggcaagctggatgaggggatgagcctctcggaagccacccgcgccgcg
cgcgagctgggctataccgagccggatccgcgtgacgacctttccggtatggacgtggcg
cgcaagctgctgatcctcgcgcgtgaaacgggccgcgagcttgagctttcggatatcgtg
attgagcctgtcctgccggcagaatttgacagcagcggtgatgtcgctgcctttatggcc
agtttgccgcagcttgacgacgcgtttgccgcgcgcgttgcaaaagcccgtgatgaaggt
aaggtattgcgctatgttggcaacattgaagaagatggcgtgtgccgggtgaagattgcc
gaagtggatggcaacgacccgctgtacaaagtcaaaaacggcgaaaacgccctcgcgttt
tacagccactattatcagccactgccgctggtgcttcgcggctatggcgcagggaacgat
gttacggcggcgggtgtgtttgccgatctgctgcgtaccctgtcatggaagttaggagtt
taa
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