Enterobacter sp. YSU: H2Z33_04680
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Entry
H2Z33_04680 CDS
T11024
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
enty Enterobacter sp. YSU
Pathway
enty00260
Glycine, serine and threonine metabolism
enty00261
Monobactam biosynthesis
enty00270
Cysteine and methionine metabolism
enty00300
Lysine biosynthesis
enty01100
Metabolic pathways
enty01110
Biosynthesis of secondary metabolites
enty01120
Microbial metabolism in diverse environments
enty01230
Biosynthesis of amino acids
Module
enty_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
enty_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
enty_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
enty00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
H2Z33_04680 (thrA)
00270 Cysteine and methionine metabolism
H2Z33_04680 (thrA)
00300 Lysine biosynthesis
H2Z33_04680 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
H2Z33_04680 (thrA)
Enzymes [BR:
enty01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
H2Z33_04680 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
H2Z33_04680 (thrA)
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Paralog
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
DUF8747
DUF8010
DUF6247
Motif
Other DBs
NCBI-ProteinID:
QPX98635
LinkDB
All DBs
Position
complement(969213..971675)
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LPNISDAERIFADLLQGLADAQPGFPLAQLKSTVELEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKLSIAIMAGVLEARGHHVTVIDPVEKLLAVGHYLESTVDIAESTRRIAASKIP
SDHMILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTISPIAQFQIPCLIKNTGNPQAPGTLIGASAD
EDELPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRNGISVVLITQSSSEYSISF
CVPQGDCLRARRALEEEFYLELKEELLEPLSIQERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVDNDDATTGVRVVHQMLFNTDQVIELFLVGVGGVGGAL
LEQVKRQQEWLKKKHIDLRVCGIANSKALLTNVHGLNLENWQAELEEAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRLAASKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELQRFSGILSGSLSFIFGKLDEGMSLSEATHAA
RELGYTEPDPRDDLSGMDVARKLLILARETGRELELSDIVIEPVLPAEFDDSGDVSAFMA
RLLQLDDAFAARVAKARDEGKVLRYVGNIEEDGVCRVKIAEVDGNDPLYKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagttcggcggtacgtcagtggcaaatgcagaacgttttctgcgtgtt
gccgatatcctggaaagcaacgccaggcaggggcaggttgccaccgtgctctctgccccg
gccaaaatcacgaaccacctggtggcgatgattgaaaaaaccatcggtggtcaggatgca
ctaccgaacatcagcgacgccgagcgtatctttgccgatctgcttcaggggctggccgac
gcccagcctggtttcccgctggcgcagctgaaaagcaccgttgaacttgaatttgcccag
attaaacacgttcttcacggtatcagcctgcttggtcagtgcccggacagcatcaacgcg
gcgctgatttgccggggtgaaaaactctctatcgccatcatggcaggcgtgctggaagcg
cgcggtcaccacgtgacggtcatcgatccggttgaaaaactgctggctgtgggccactac
cttgaatccaccgtcgacattgccgagtcgacacgccgtattgcggcgagcaaaatcccg
tctgaccatatgatcctgatggcaggctttaccgccggtaacgagaagggcgaactggtg
gtgctggggcgtaacggctctgactactccgccgccgtgctggcggcctgcttacgcgcg
gactgctgtgagatctggactgacgtcgacggcgtttatacctgcgatccgcgccaggta
ccggacgccaggctgctgaagtcgatgtcgtaccaggaagcgatggagctttcctacttc
ggcgctaaagttcttcacccgcgtaccatctccccgattgcccagttccaaatcccttgc
ctgattaagaataccggtaaccctcaggcgccgggcacgctgattggcgccagcgcggat
gaagatgaactgccggtgaaaggcatttctaacctcaataacatggcgatgttcagcgtc
tccggcccggggatgaagggcatggtcggcatggcggcacgcgtatttgccgctatgtcc
cgcaacgggatctccgtggtgctgatcacgcagtcttcttccgaatacagcatcagcttc
tgcgttccgcagggtgattgcctgcgtgcccgtcgcgcgctggaagaagagttctatctg
gagctgaaagaagagctgctggagccgctctcgattcaggagcgtctggcgattatctcg
gtggtcggcgacggcatgcgcaccctgcgcggtatctccgccaaattctttgccgcgctg
gcgcgggctaatatcaatatcgtggcgattgcccagggctcatcagagcgttccatttcc
gttgtcgtggataacgatgacgccactaccggcgtgcgcgtggtgcatcagatgctgttc
aacaccgaccaggtgattgagctgttcctggtgggcgtcggtggtgtcggtggcgcgctg
ctggagcaggtgaagcgccagcaggagtggcttaagaagaaacatatcgatttgcgcgtt
tgcggcattgcgaactcgaaagcgttgctgactaacgtccacggtctgaatctggaaaac
tggcaggcggagctggaagaggcgaaagagccatttaacctgggccgcctgatccgcctg
gtgaaagaatatcacctgcttaacccggtgattgttgactgtacctccagccaggcggtg
gccgatcagtacgccgacttcctgcgcgaagggttccacgtggtgacgccgaacaaaaag
gccaacacctcgtcgatggattactatcaccagctgcggctggcggcgagtaagtcgcgc
cgtaagtttctgtatgacaccaacgtgggcgcgggcctgccggtcatcgagaacctgcaa
aacctgctgaacgcgggcgacgaactacagcgtttctccggcatcctctccggctccctg
tcgtttatcttcggcaagctggacgaagggatgagcttgtcggaagccacccacgccgcg
cgcgagctgggctacaccgagccggatccgcgcgacgacctctccggcatggacgtggcg
cgtaagctgctgatcctggcgcgcgaaactggccgcgagctggagctttcggatatcgtg
attgagccggtgctgccagcagaatttgatgacagcggtgacgtcagcgcctttatggcc
aggttgctgcagcttgacgacgcctttgccgcacgcgttgcgaaagcccgtgatgaaggt
aaggtattgcgctatgttggcaacattgaagaagacggcgtctgccgggtgaagattgcc
gaagtggatggcaacgatccgctgtacaaggtgaaaaacggcgagaacgccctggcgttc
tacagccattattatcagccactgccgctggtgcttcgcggctatggcgcagggaatgat
gtgacggcggcgggcgtgtttgccgatctgctgcgtaccctgtcatggaagttaggagtt
taa
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