Enterobacter sp. E20: NI40_003495
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Entry
NI40_003495 CDS
T04118
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
enx
Enterobacter sp. E20
Pathway
enx00300
Lysine biosynthesis
enx00550
Peptidoglycan biosynthesis
enx01100
Metabolic pathways
enx01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
enx00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NI40_003495 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NI40_003495 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NI40_003495 (murF)
Enzymes [BR:
enx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NI40_003495 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
ALL16250
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Position
747702..749060
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AA seq
452 aa
AA seq
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MISITLSQAAAILQGDLRGQDLTIDAVTTDTRKITAGCLFVALKGERFDAHDFAEQAKEN
GAGALLVSRKLDIDLPQIVVKDTRLAFGELAAWVRQQVPTRVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTKEHEFAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLEGVAKAKGEIYTGLPDDGIAILNADNNDWLNWQSIIGSRKTWRFS
PNAANSDFTATNIHVTSHGTEFTLTTPTGGVDVLLPLPGRHNIANALAAAALSTAVGASH
EAIKTGLANLKAVPGRLFPIQLSENKLLLDDSYNANVGSMTAAVQVLSEMPGYRIMVVGD
MAELGDESEACHTQVGEAAKAAGLDCVLSAGKLSQAISQASGVGEHFADKAALIARLKAL
ITEKQIVTVLVKGSRSAAMEEVVHALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcatcacgttaagccaggccgctgccatcctgcagggcgacctgcgcgggcaa
gacctgaccattgatgccgtaacgacggacacccgcaaaatcaccgcaggctgtctgttt
gtggcgctgaaaggcgagcgttttgacgcgcatgattttgcggaacaggccaaagagaac
ggcgccggtgcgctgctcgtcagccgcaagcttgatatcgatctgccacaaattgtggtg
aaagatacgcgtctcgcgttcggtgagctggccgcctgggttcgccagcaggtccctacg
cgcgttgtcgccttgaccggttcatcaggcaagacgtcggtgaaagagatgacggcggcg
atcctcagccagtgcgggaatacgctttataccgcgggcaacctcaataatgacatcggc
gtgccgatgacattactccgcctgaccaaagaacatgaatttgcggtgatcgagttaggg
gcaaaccaccagggcgaaatcgcctggaccgtgagcctgactcgcccggaagccgcgctg
gtgaataaccttgcggctgcgcatctggaaggctttggctcgctggaaggcgtagcgaaa
gccaaaggtgagatttacaccggcctgccggatgacggtatcgccattctgaacgccgac
aacaacgactggctgaactggcaaagcattattggttcgcgtaaaacctggcgcttctcg
ccgaatgcggccaacagtgattttaccgcgaccaatatccatgtgacgtcgcacggtacg
gagttcaccctcaccaccccaacgggtggcgtagatgtgctgctgccgctgccgggtcgc
cataatatcgccaatgcgcttgcggcggcggcgttgtcgacggcagtgggcgcgtcgcat
gaagcgattaagaccgggctggcgaacctgaaagccgtgccgggacgtctgttcccgatt
cagctttcggaaaacaagctgctgctggacgactcctacaacgcgaacgtgggctcaatg
acggcggcggtgcaggtgttatctgaaatgccgggctaccgcatcatggtggtgggcgat
atggcagagctgggcgacgaaagcgaagcctgccatacccaggtcggtgaagcggcgaaa
gcggcggggctggactgcgtgctgagcgcaggaaaactgagccaggcgattagccaagcc
agcggcgttggcgagcattttgctgataaagccgcgttgatagcgcgccttaaagcgttg
attactgaaaaacaaattgtgactgtgttagtgaaaggttcacgtagtgccgccatggaa
gaggttgtgcacgcattacaggagaacgggacatgttag
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