Enterobacter sp. E20: NI40_017260
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Entry
NI40_017260 CDS
T04118
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
enx
Enterobacter sp. E20
Pathway
enx00290
Valine, leucine and isoleucine biosynthesis
enx00620
Pyruvate metabolism
enx01100
Metabolic pathways
enx01110
Biosynthesis of secondary metabolites
enx01210
2-Oxocarboxylic acid metabolism
enx01230
Biosynthesis of amino acids
Module
enx_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
enx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
NI40_017260
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NI40_017260
Enzymes [BR:
enx01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
NI40_017260
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GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
ALL18832
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Position
3717916..3719571
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AA seq
551 aa
AA seq
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MLNTPADKYQPYPTLSLPDRRWPEQRITRAPRWLSTDLRDGNQALAEPMDSTRKLQFWDL
LLGCGFKEIEVAFPSASQTDFNFVRQLIEENRIPDDVTIQVLTQAREDLIHRTFESLRGA
KQATVHLYNATAPLFRRLVFGMEKAQIVELATRSTRLIRQLCEENPDTRWQYEYSPETFC
FTEPEFALEICEAVAEMWQPCDERPMVINLPATVEVSTPNVYADQIEYFCRHFSRRRDVC
ISVHPHNDRGTGVASAELAVMAGADRVEGCLFGNGERTGNVCLVTLAMNLYSQGVSPNLD
FSDMNRIVEVVEACNQLPVHPRHPWAGRLAYTAFSGSHQDAIKKGFDARRPGDRWEMPYL
PVDPQDIGCTYEAVIRVNSQSGKSGSAWLIEQNHGLKLPRTLQQDFSQHVQQETDRHGKE
MTQNALWQLFRTRYGLVASPQFALQSYRSDSQQDGQLRLTASIATQGGTRQLEGQGNGLL
SAAAHGLSRWVNAPFVIKDYHEHTLGERSDSRSVAYIRCLFQDGSSRWGVGIDSDVARAS
LQALLNAVSRS
NT seq
1656 nt
NT seq
+upstream
nt +downstream
nt
atgctgaacacacccgccgacaagtaccaaccctatccgaccctttccctgcccgaccgc
cgctggccggagcaacgcattacccgcgcgccgcgctggctctcaaccgacttacgcgac
ggcaaccaggcccttgccgagccgatggacagcacccgcaagctgcagttctgggatctg
ctgctgggctgcggattcaaagaaattgaggtggctttcccatccgcctcgcagaccgac
ttcaacttcgttcgccagctgattgaagagaaccgcatcccggatgacgtcacgattcag
gtattaacccaggcgcgggaagatctcatccatcgcactttcgaatccctgcgcggtgcg
aaacaggccaccgtccatctgtataacgccaccgccccgctgttccgccgcctggtgttc
ggcatggagaaagcgcaaatcgttgagctggcgacgcgctccacgcggctaattcgtcag
ctgtgtgaagagaacccggacactcgctggcagtatgagtattccccggagaccttctgc
tttaccgagccggagtttgcgctggagatttgtgaagccgtggcggagatgtggcagccg
tgcgacgaacggcccatggtgatcaacttacccgcaaccgtcgaagtgagcacgccgaac
gtctatgccgaccagatcgagtatttctgtcgccacttcagccgccgccgggatgtctgc
atcagcgtgcatccgcataacgaccgcggtaccggcgtcgccagcgccgagctggccgtg
atggcgggggcagaccgcgtggagggctgtctgtttggtaacggcgagcgcacgggcaac
gtctgcctggtgacgctggcgatgaacctctacagccagggcgtcagcccgaatctcgac
tttagcgatatgaaccggatcgtggaagtggtggaagcctgcaaccagctgccggtgcat
ccgcgccacccgtgggccggacggctggcctataccgccttctccggctcgcaccaggac
gcgatcaaaaaaggctttgatgcccgcaggcctggcgatcgctgggagatgccgtatctg
cccgtcgatccgcaggatatcggctgcacctacgaagcggtgatccgcgtaaacagccag
tcagggaaaagcggcagcgcgtggctcatcgaacagaatcatggcctgaaattaccccgc
accctgcagcaggatttcagccagcacgtgcagcaggaaaccgatcgccacggaaaagag
atgacgcaaaatgcgctgtggcagcttttccgcacccgctacggcctggtagcttcgccg
cagtttgcgctgcaatcctaccgcagcgacagccagcaggacggccagctgcgtttgacg
gcaagcatcgctacgcaggggggaacgcgtcagctggaaggtcagggtaacggtctgctc
tccgccgccgctcacggcttaagccgctgggtcaacgccccgttcgtgattaaggattat
cacgagcatacgttaggcgaacgcagcgacagccgctcggtggcctacatccgctgcctg
ttccaggacggcagcagccgctggggcgtgggcatcgacagcgacgtggcgcgcgcgtcg
cttcaggcgctcttaaacgccgtcagtcgttcttaa
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