KEGG   Eucyclogobius newberryi (tidewater goby): 140368575
Entry
140368575         CDS       T10929                                 
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
eny  Eucyclogobius newberryi (tidewater goby)
Pathway
eny04010  MAPK signaling pathway
eny04012  ErbB signaling pathway
eny04020  Calcium signaling pathway
eny04510  Focal adhesion
eny04520  Adherens junction
eny04530  Tight junction
Brite
KEGG Orthology (KO) [BR:eny00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    140368575 (erbb2)
   04012 ErbB signaling pathway
    140368575 (erbb2)
   04020 Calcium signaling pathway
    140368575 (erbb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    140368575 (erbb2)
   04520 Adherens junction
    140368575 (erbb2)
   04530 Tight junction
    140368575 (erbb2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:eny01001]
    140368575 (erbb2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:eny04147]
    140368575 (erbb2)
   04090 CD molecules [BR:eny04090]
    140368575 (erbb2)
Enzymes [BR:eny01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     140368575 (erbb2)
Protein kinases [BR:eny01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   140368575 (erbb2)
Exosome [BR:eny04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   140368575 (erbb2)
CD molecules [BR:eny04090]
 Proteins
  140368575 (erbb2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 Haspin_kinase ABC1
Other DBs
NCBI-GeneID: 140368575
NCBI-ProteinID: XP_072311610
LinkDB
Position
Unknown
AA seq 1292 aa
MDAVRSLAFVGAVLLGVTGTLGREVCLGTDMKLALPSSLENHYETLRLLYTGCRVVHGNL
EITHLHGNPDLSFLQGIVEVQGYVLVAHVSVDLVPLDNLRIIRGSQLYNDSFALAVLENT
QAGRGLRTLRLRSLTEILVGAVYIWSNPQLCFPDPQSIVWRDTLDEKNVHAEKHKLQKRA
ANCPGCDSSCKIACWGETAQDCQTLTRIKCASDCQRCKGPLSSDCCHLQCAAGCTGPKDS
DCLACRHFNDSGVCRENCPAPTIYDPVTYQTKPNPHKKFSFGATCVKTCPYNYLAMDACT
LVCPKANQEVIVTNPDGSETQKCENCEGDCPKVCYGLGMEHLGAVTMVTAANVEQFNSCK
KIFGSLAFRPQSFTSDPQTNTSGVTLDQLMAFRSLEEITGYLYIDAWPENWTNLSVFENL
KVIRGRMLHKGVFSLAVQNLHIESLGLRSLHSVSGGLVMLHNNSQLCYTSSLPWDTLLHP
TQGPHRIVSQNQDPQTCETQGHVCHPLCEGGCWGPGPSQCVSCKYFQRGTECIEQCNVDQ
GLVREYVDGSLCVACHAECEPLNNTASCDGPGSNMCTVCQHFKDGDFCVDRCPSGVKVDQ
IYIWKYSDADGNCQPCNTNCTLSCTLMDERGCPIHTGPGTTIAAAVGGMVLFCILLALLI
FYLKRQKKLRRKETLRRILQEHELVEPLTPSGASPNQAQMRILKETELKKLRVLGAGAFG
TVFKGVWNPVGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVASPYVCRLLGICLTS
TVQLVTQLMPYGCLLDYVRENKDRIGSQFLLNWCVQIAKGMSYLEEVRLVHRDLAARNVL
VKNPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILHRRFTHQSDVWSYGVTV
WELMTFGAKPYDMIPAREIPEVLEGGERLPQPPICTIDVYMIMVKCWMIDPDSRPRFKDL
VNDFSVMARDPPRYVVIQNDEQMSTSSPVDSQFFRMLMEEEGTNISELLDPDEYLVPQPN
MFQRSQTDGVQSNGPSRHQSYRSRDQGLDLDPSLTNGPRNMNSSMSTLSRAQYPTLPLGA
STSNGLWSQYPILARSPSAGGQSDSVFLDGSPDNPSLPPASPGRYSKDPTYPNGSLGDLE
MDGPVTFPPPHYNHHSLPRPPRYHVNHALPEYVNQDIHNLRLMMPERPTTLPRKGSKIDR
RLPNGLGSGHSVENPGYLVPSAPGTSTSPAFDNPYYLDLVAKANAVASPSLEVNGDLETD
GEAVSRQLNGFVTPTAENPEYLGLADTWSGYT
NT seq 3879 nt   +upstreamnt  +downstreamnt
atggacgcggtgagaagtttggcgtttgtcggggccgtgctcctcggagtgacgggcacg
ttgggcagagaagtgtgtctgggcaccgacatgaaactggccctgccctccagtctggaa
aaccactacgagactctgaggctgctgtacaccgggtgcagggtcgtccacggcaacctg
gagataacacacctccacggcaacccagacctctcctttctacagggtatagtggaggtg
caggggtacgtcctcgtggctcatgtatccgtggacctggtgccactggacaaccttcgc
attatccgggggtcccagctgtacaacgacagcttcgctctggctgtacttgagaacact
caggcgggacgagggctcaggacgctcaggctgcgcagtctcacagagatcctcgtgggc
gcggtttatatttggagcaaccctcagctgtgtttcccggacccccagagcatcgtgtgg
cgggacactttagacgagaagaacgttcacgcagaaaaacacaagttacagaagagggcc
gctaactgtcccggttgtgactcttcttgtaaaatagcctgctggggggagaccgcacag
gactgccaaacactgacccgcattaaatgtgcgtctgactgtcagcgctgtaaaggtcct
ctctccagcgactgttgtcatttgcagtgcgccgctggatgcactggccccaaagactca
gactgtctggcatgtcgtcactttaatgacagtggagtttgtagagaaaattgtcctgct
cccaccatttacgaccctgtgacctatcagaccaaacccaacccacacaagaagtttagc
tttggggccacctgtgtgaagacctgtccatataactacctggctatggatgcttgcact
ttggtttgtccaaaagcaaaccaggaggtaatcgtcacaaacccggacggaagtgagacg
cagaagtgtgaaaattgtgaaggcgattgccctaaagtgtgctatggtctgggcatggag
cacctcggagcggtcactatggttaccgctgccaatgtggaacagttcaactcttgcaag
aagatcttcggcagcctggccttccgccctcagagcttcacaagtgaccctcagaccaac
acgtcaggcgtcactctggaccagctcatggctttcaggagcctggaggaaataacagga
tatctttatattgatgcgtggcctgaaaactggactaacttgagcgtttttgaaaacctg
aaggtgattcgtggaaggatgcttcacaagggtgtcttttcactggctgttcagaacctc
cacattgagtctttggggctgcgatcacttcacagtgtcagtgggggtttggtcatgttg
cacaataactctcagctgtgctacaccagctctctgccctgggacacgctcctgcacccc
actcagggcccacatcgcatcgtcagccaaaaccaagacccccagacgtgtgagacacaa
gggcatgtgtgtcacccactgtgtgaaggagggtgctggggtcccgggccgagccagtgt
gtgtcttgcaaatatttccagcgtgggacagagtgcatcgagcagtgcaatgttgaccaa
ggtcttgttcgtgaatatgttgatggatctttgtgtgtggcttgtcatgcagagtgtgag
cctctcaataacactgcctcctgcgacggcccgggctccaacatgtgcacagtgtgtcaa
cacttcaaagatggagacttttgtgtggatcgctgtcccagtggagtcaaagtggatcag
atttatatttggaaatacagtgacgctgatgggaactgccagccctgcaacaccaactgc
accctgtcttgcactttgatggatgaaagaggatgtccaattcacactggaccagggact
accattgcagctgctgttggtggcatggtgctgttctgtatcctcttggctctgctcatt
ttttacctgaagagacagaagaagctgaggaggaaagagactttgaggagaatcctgcag
gagcacgagctggtggaacctttgactcccagtggtgcgtctccaaaccaggctcagatg
aggatcttgaaagaaactgagctgaagaaactgcgagtgcttggagctggtgcttttggt
actgtcttcaagggtgtgtggaaccctgttggagaaaacgtaaaaatcccagtagccatt
aaagttttacgagagaacacttcaccgaaggccaacaaagagattttggatgaggcgtac
gtgatggctggagtcgccagtccttatgtgtgtcgtctcttggggatttgtctgacctcc
acagttcagttggtcactcagctcatgccctacggctgcctgctcgactatgtccgagaa
aacaaagaccgtatcggctctcagtttctactcaattggtgtgtccagattgccaaggga
atgagctatctggaggaggtgcgtctggtccacagagatctggccgctcgaaatgttctg
gttaaaaatcccaaccacgtgaagatcacagactttggtttagctcgacttctcgatata
gatgagaccgaatatcacgctgacggggggaaggtgccaattaaatggatggctttggag
tctattctgcacagaaggtttactcatcagagcgacgtgtggagctatggggtgactgtc
tgggagctgatgacatttggtgcaaaaccttatgacatgatcccagcaagggaaatccca
gaagtcctggaggggggagagagactgccccaaccaccaatctgcaccatcgacgtctac
atgatcatggtcaaatgttggatgattgatccagacagcagaccacgcttcaaagacctt
gtgaacgacttcagtgtcatggccagagatccaccgcgatatgtggtcatacagaacgac
gagcagatgagcacgtccagtccggtggacagtcagttcttccggatgttgatggaggaa
gagggcacaaacataagtgagctcttagatcctgacgagtacctggtcccacagccaaat
atgttccagaggagtcagacagacggggtccagtccaacgggccatcccgacaccagtca
tacaggagtcgagaccagggtttggatctggacccctctctcaccaacggcccgcgcaac
atgaattcttcaatgagcactctgagcagggcgcagtaccctactctgcccctaggagcc
agtacctcaaacggactctggtcgcagtacccgattctggcccgcagcccctcagcagga
ggccagtcagactctgtgttcctggatggatcaccggacaacccctcactgccccctgcc
agcccgggacgttacagcaaggaccccacctatcccaacggcagcctgggcgatttggag
atggacggtcctgtcacattccctcctccccattacaaccatcactcccttcccaggcct
cctcggtatcatgtcaaccatgccctaccagaatatgtcaatcaagatattcacaatctt
cgactaatgatgcctgagcgtcctaccacacttccccggaaaggctccaaaatcgaccgc
cgccttcccaacggcctcggctccggacacagtgtggagaaccccggatatttggtccct
agcgcccctgggacatctacctctcctgcatttgataacccctattacttggaccttgtg
gcaaaggccaacgcagtcgcatctccatcactggaagtcaatggggacctcgaaacagac
ggagaagcagtttccaggcagctcaatgggtttgtaacgcccacagcagaaaacccagaa
tatctcggactagcagatacctggagtggttatacttga

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