Escherichia coli O111 H- 11128 (EHEC): ECO111_3283
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Entry
ECO111_3283 CDS
T01097
Symbol
purL
Name
(GenBank) phosphoribosylformyl-glycineamide synthetase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
eoi
Escherichia coli O111:H- 11128 (EHEC)
Pathway
eoi00230
Purine metabolism
eoi01100
Metabolic pathways
eoi01110
Biosynthesis of secondary metabolites
Module
eoi_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
eoi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
ECO111_3283 (purL)
Enzymes [BR:
eoi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
ECO111_3283 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-ProteinID:
BAI37095
LinkDB
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Position
complement(3252238..3256125)
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AA seq
1295 aa
AA seq
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MMEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLNAPLNDDEHAQLERLLK
YGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTLT
NEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGL
ALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWVIDGEQQPKSLFKM
IKNTFETTPDYVLSAYKDNAAVMEGSEVGRYFADHETGRYDFHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI
RADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL
EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELYLSLHDRHFDNQPIDL
PLDVLLGKTPKMTRDVQTLKAKGDALVREGITIADAVKRVLHLPTVAEKTFLVTIGDRSV
TGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEAL
TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS
MKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGA
TALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFA
GHCGIDADIGSLGDDRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVGQAVS
GDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVK
LSFDINEDVAAPFIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRT
GLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQM
MSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGR
VEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITSVTTESGRVTIMMPH
PERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattctgcgtggttcgcctgcactgtcggcattccgaatcaacaaactgctg
gcacgttttcaggctgccaggctcccggttcacaatatttacgccgagtatgtccatttt
gctgacctcaatgcgccgttaaacgatgatgagcacgcacaacttgaacgcctgctgaaa
tatggcccggcactcgccagccacgccccgcaaggcaaactcctgctggtgaccccgcgt
cctggcaccatctctccctggtcttcgaaagcgaccgatattgcccataactgcgggcta
caacaggtaaaccgccttgagcgcggcgttgcttactatatagaagccggtacgctgacc
aatgaacaatggcagcaggttaccgctgaactgcacgaccgcatgatggaaacggtcttt
tttgctttagatgatgcagagcagctgtttgcacaccatcaaccgactccggtcaccagc
gttgatttgctggggcagggccgtcaggcgctaatcgacgctaacctgcgtcttggcctg
gcactggcggaagatgaaattgactatctgcaggatgctttcacaaagcttggtcgtaac
ccgaacgacatcgagctgtatatgttcgcccaggcgaactccgagcactgccgccacaag
atttttaacgccgattgggttatcgacggtgagcaacagccgaaatcgctgtttaagatg
atcaaaaacaccttcgaaaccacgccagattacgttctctctgcttataaagataacgcc
gccgtaatggaaggttctgaagtgggccgctactttgctgaccacgaaacgggccgctac
gatttccatcaggaaccggcgcatattctgatgaaagtcgaaactcacaaccacccgacg
gcgatttctccgtggccgggcgcggcgaccggttccggcggtgaaatccgcgatgaaggt
gccaccgggcgcggcgcgaagccgaaagcgggtttggttggtttctccgtttccaacctg
cgaattcctggcttcgaacagccgtgggaagaagatttcggtaagcctgagcgcattgtc
accgcgctggacatcatgaccgaaggcccgctgggcggcgcggcgtttaacaacgaattt
ggtcgtccggcactgaatggctacttccgtacttatgaagaaaaagtgaacagccacaac
ggcgaagagctgcgcggttatcacaaaccgatcatgctggcgggcgggatcggcaacatt
cgcgccgatcacgtacaaaaaggcgagatcaacgtcggtgcgaagctggtcgttctcggc
ggcccggcaatgaacatcggtcttggcggcggagcggcgtcttccatggcgtcaggtcag
tctgatgccgacctcgactttgcttccgtacagcgcgacaacccggagatggagcgtcgt
tgccaggaagtgatcgaccgttgctggcagcttggtgatgctaacccaattctgtttatc
cacgacgtcggtgcgggcggtctttctaacgcgatgccggagctggtgagcgacggcgga
cgcggcggtaaatttgaactgcgcgatattctaagcgacgaaccgggcatgagcccgctg
gaaatctggtgtaacgaatcccaggaacgctacgtgctggcggttgctgccgatcaatta
ccgctgtttgacgaactgtgtaagcgtgagcgcgcaccctacgcggtgattggtgaagcg
accgaagaactgtatctttctctgcacgatcgtcattttgataatcagccgatcgatctg
ccgctggacgtcctgcttggtaaaacgccgaagatgacccgcgatgtacaaacgctgaaa
gcgaagggcgatgcgctggtccgtgaagggatcaccattgcagacgcggtgaaacgcgta
ctgcatctgccgaccgtggcggagaaaactttcctggtgaccatcggtgaccgcagcgta
actggcatggtagcgcgcgatcagatggtgggtccgtggcaggtgccggtcgctaactgc
gcggtcactaccgccagcctcgacagctactacggtgaagcgatggcgattggcgagcgt
gcgccggttgcgctgctggatttcgccgcctctgcccgtctggcggtcggtgaagcgtta
accaatattgccgcaacacagattggcgatatcaaacgcattaaactttccgccaactgg
atggcggcggcaggccaccctggtgaagatgcgggcctgtatgaagccgttaaagccgtg
ggcgaagagctttgtccggcgctgggcctgacgatcccggtgggtaaagactctatgtcg
atgaaaacccgctggcaggaaggtaacgaagagcgcgaaatgacgtcgccgctgtcgctg
gtgatttctgcatttgcccgcgtggaagatgtacgtcacaccatcacgccgcagctttct
accgaagataacgcactgctgctgattgatttgggcaaaggcaataacgcgctgggcgca
acggcgctggcgcaggtttatcgtcagcttggcgacaaaccggcagatgtacgcgatgtc
gcgcaactgaaaggcttctatgacgcgattcaggcgctggttgcacagcgtaagctgctg
gcgtatcacgaccgctctgatggcggtctgttggtcacactggcggaaatggcctttgct
ggtcattgtggcattgatgcggatatcggctctctgggtgacgatcgcctggcggcgttg
tttaacgaagaactgggtgcggtgattcaggttcgtgccgctgaccgtgaagcggtcgag
tccgtactggcacagcatgggcttgctgattgcgtccattatgttgggcaggcggtttcc
ggtgaccgttttgtgattaccgccaacgggcagactgtattcagcgaaagccgcactacg
ttgcgtgtctggtgggcagaaactacctggcagatgcagcgcctgcgtgacaacccggag
tgtgctgaccaggagcaccaggcgaaatcaaacgacgccgatccgggcctgaatgtaaaa
ctgtcgttcgatatcaacgaagatgtggcagcaccgtttattgccactggcgcgcgcccg
aaagttgccgtactgcgtgagcagggcgtgaactcgcatgttgaaatggcggcagctttc
caccgtgcaggctttgatgctatcgacgtgcatatgagtgacctgctggctggacgcacg
ggcctggaagatttccacgccctggtcgcgtgcggtggtttctcctacggtgatgtgctg
ggtgccggtgaaggttgggcgaagtcaatcctgttcaatgaccgtgtacgcgatgagttt
gcaaccttcttccaccgtccgcaaacgctggcgctgggggtatgtaacggttgccagatg
atgtctaatctgcgtgaactgatcccaggtagtgagttgtggccacgttttgtgcgcaat
acctccgatcgctttgaagcgcgtttcagcctggttgaagtgacccaaagcccgtcgctg
ctgttgcaggggatggtgggctcgcaaatgccgattgctgtctctcacggtgaagggcgc
gtggaagtgcgtgatgcggcgcatctggcggcactggaaagcaaagggctggtggcactg
cgctatgtcgataacttcggcaaagtcactgaaacctacccggctaacccgaacggttct
ccgaacggtattacgtcggttacgactgaaagtggtcgagtcaccattatgatgccgcac
ccggaacgtgttttccgtactgtcagcaactcctggcatccggaaaactggggcgaggat
ggcccatggatgcgcattttccgcaatgcgcgtaagcagttggggtaa
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