Erwinia pyrifoliae DSM 12163: EPYR_00726
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Entry
EPYR_00726 CDS
T02121
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
epr
Erwinia pyrifoliae DSM 12163
Pathway
epr00260
Glycine, serine and threonine metabolism
epr00261
Monobactam biosynthesis
epr00270
Cysteine and methionine metabolism
epr00300
Lysine biosynthesis
epr01100
Metabolic pathways
epr01110
Biosynthesis of secondary metabolites
epr01120
Microbial metabolism in diverse environments
epr01230
Biosynthesis of amino acids
Module
epr_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
epr_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
epr_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
epr00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
EPYR_00726 (thrA)
00270 Cysteine and methionine metabolism
EPYR_00726 (thrA)
00300 Lysine biosynthesis
EPYR_00726 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
EPYR_00726 (thrA)
Enzymes [BR:
epr01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
EPYR_00726 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
EPYR_00726 (thrA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-ProteinID:
CAY73097
LinkDB
All DBs
Position
795737..798199
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNAQQGQVATVLSAPAKITNHLVAMIEKTISGQDA
SANISDAERIFAGLLQGLTDAQPGFAYDRLKAVVDQEFVQLKQVLHGIALLGQCPDSVNA
AIICRGEKLSIAIMEGVLQARGHGVSVINPVEQLLAIGHYLESTVDIAESTRRIAARQIP
PDDMVLMAGFTAGNERGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTGNPQAPGTLIGGNGS
DDDNPVKGITNLNNMAMFNVSGPGMKGMVGMAARVFAAMSRSGVSVVLITQSSSEYSISF
CVSQSDLPRARRVLEEEFYLELKNGLLEPLDVMEQLAVISVVGDGMRTLRGISAKFFSAL
ARANINIVAIAQGSSERSISVVVDNSQAITGVRVVHQMLFATDQVIEVFVIGVGGVGAAL
IDQLHRQQKWLKNKHIDLRVCGIANSRALLTNVHGIPLDNWQEQLKSAQKPFDLGRLNHL
VQEYHLLNPVIVDCTSNQQVADRYADFLADGFHVVTPNKKANTSSYNYYQQLRAAAAKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELISFSGILSGSLSFIFGKLDEGVSLSDATQMA
REMGFTEPDPRDDLSGMDVARKLLILAREAGYQLELSDIDIEAVLPPELTAIADVDEFMA
RLPELDDGFAAQVSSARDAGKVLRFVGAIEEDGACRVKIAAVDGNDPLYKVKNGENALAF
YSRYYQPIPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgctgaaattcggtggaacctcggtagccaatgcggaacgttttctgcgtgtg
gctgacattttggaaagcaatgcacaacagggacaggttgctaccgtgttgtccgcgcca
gcaaaaattaccaaccatctggtggcgatgattgagaaaaccattagcggccaggatgcc
tcagcgaatatcagcgatgccgagcgtattttcgccgggctgttgcaggggctgaccgac
gcccagccgggatttgcttatgaccgtctgaaagcggtggtggaccaggaatttgtccag
ctcaaacaggtgctgcatggtattgcgctgctggggcagtgcccggacagcgtcaatgcg
gccattatctgccggggtgaaaagctctctatcgccattatggaaggtgtgttgcaggcg
cgcggccacggggttagcgttataaacccggtcgaacagctgttggccatcggtcattat
ctggaatcgaccgttgatattgccgagtccacccgccgcattgctgcacgacagatcccg
cccgatgatatggtgctgatggccggcttcaccgccggtaatgagcgtggggagctggtg
gtgctgggacgcaacggctctgattactctgcggcggtgctggctgcctgtctgcgtgcc
gactgttgcgaaatctggaccgatgttgacggcgtgtacacctgtgacccgcgtcaggta
ccggatgcacggctgctgaagtcgatgtcctatcaggaagcgatggagctttcctatttc
ggtgctaaagttcttcacccacgcactatcgcccctatcgcccagtttcagatcccctgc
ctgatcaaaaataccggcaatccgcaggcacccggcaccctgataggcggtaacggcagc
gatgatgacaacccggttaaaggcatcactaacctcaacaatatggcgatgttcaacgtc
tccggcccggggatgaagggcatggtcggcatggcggcacgcgtttttgccgccatgtca
cgcagtggggtttcagtggtgctgatcacccaatcctcctctgaatacagcatcagcttc
tgtgtatcgcagagcgatttgccgcgtgcgcgccgggtgctggaagaagagttctatctg
gaactgaaaaacggcctgttggaacctctggatgtgatggaacagctggcggtaatttca
gtggtgggtgacggtatgcgcacgctgcgcggcatctccgccaagttcttttcagccctg
gcgcgggccaatatcaatatcgttgcaatcgctcaaggctcgtccgagcgttccatctcg
gtggtggtagataactctcaggcgattaccggcgtgcgcgtggttcatcagatgctgttt
gccaccgaccaggtgatagaagtcttcgtgatcggcgttggcggcgtgggtgccgcgttg
atcgaccagctgcatcgccagcaaaaatggttgaaaaataagcatatcgatctgcgcgtc
tgtggcattgccaactcgcgagcgctgctgactaacgttcacggtattccgctggataac
tggcaggaacagcttaagtccgcgcagaaaccgtttgacctcggccgcctgaatcacctg
gtgcaagagtatcacctgctcaatccggtgattgtcgactgtacttccaaccagcaggtg
gcggatcggtacgccgatttcctcgccgacggttttcatgtggtgacgccgaacaaaaag
gccaatacttcatcgtacaattactaccagcagttgcgtgcggcagcggcaaaatcgcgc
cgcaaattcctgtacgataccaacgtcggtgccggtctgccggttatcgagaacctgcaa
aacctgctgaatgcaggggatgagctgatcagtttctccggtatcctttccggctccctg
tcgtttattttcggcaagctggatgaaggcgtttcgctgtctgatgctacccaaatggcg
cgtgaaatgggcttcaccgagccggatccgcgagacgatctgtccggtatggacgtggcg
cgtaagctattgatcctcgcgcgtgaagccggttatcagctggagctgagcgatattgac
attgaagcggtgctgccgccagagcttaccgccattgccgacgttgacgagtttatggcg
cgtttgccggagctggacgatggctttgccgctcaggtgtccagtgcccgtgacgcgggt
aaagtgttacgttttgttggtgcgattgaggaagacggggcgtgtagggttaaaatcgct
gccgttgacggtaacgatccgctgtataaagtcaaaaatggtgaaaatgcgctggcgttc
tacagccgttattaccagcctatccctctggtgctgcgtggttacggtgccggtaatgat
gtcactgcggcgggcgtgtttgccgatctgttacgtactctgtcgtggaagttgggagtt
taa
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