Equus przewalskii (Przewalski's horse): 103544560
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Entry
103544560 CDS
T04644
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
epz
Equus przewalskii (Przewalski's horse)
Pathway
epz00790
Folate biosynthesis
epz01100
Metabolic pathways
epz01240
Biosynthesis of cofactors
epz01523
Antifolate resistance
epz04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
epz00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
103544560 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
103544560 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103544560 (FPGS)
Enzymes [BR:
epz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
103544560 (FPGS)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
103544560
NCBI-ProteinID:
XP_008509608
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Position
26:31044934..31063812
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AA seq
641 aa
AA seq
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MGDSDPSCIPDSRQRGPWADPGMRAGSYQLERRQRGLSRGVHACEALRAPPGWRAGSPGM
KDARALATSWPVAERWWESTMERPGPSGRPFSAKTASFQDAVRTLNTLQTNASYLEQVKR
QRGDPQTQLEAMELFLARSGLQLEDLDQLNIIHVTGTKGKGSTCAFTERILRSYGLKTGF
FSSPHLVQVRERIRINGQPISPELFTNHFWRLYHRLQETKDGSSCVSMPAYFRFLTLMAF
HIFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGLDHTSLLGDTVEKIAWQKGGI
FKRGVPAFTVLQPDGPLAVLRDRAQQISCPLYLCPPLEALEEGGPPLTLGLEGEHQRSNA
ALALQLARCWLQQKDHQGIGELKASQPSLQWQLPLAPVFQPTSHMQHGLRDTEWPGRTQV
LRRGPLTWYLDGAHTVSSVQACVRWFRQALRGRDRPDSGPEVRVLLFNSTGDRDPAALLK
LLQPCQFHYAVFCPNLTEVSPTGNEDQQNFTVTLDQVLLRCLTHQQHWSRLDKEQASPNL
WNSPGPEPGGPASLLLAPCLPHPVSTSSLVFSCISHALQWISQGRDPVFQPPSPPRGLLA
HPVAGSGASVLREAAAIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1926 nt
NT seq
+upstream
nt +downstream
nt
atgggagattctgacccgtcctgcattcccgacagccgccagagaggcccctgggcagat
cctgggatgagagcaggaagctatcagctggagcgcaggcagaggggcctcagcagaggt
gtccacgcctgtgaagcacttcgtgccccacctggttggagagcggggagcccggggatg
aaggatgccagggccctggctacctcgtggcccgtggctgagaggtggtgggaatcaacc
atggagaggcccggcccatccgggcgtcctttctcggctaaaactgcctccttccaggat
gctgtgcgcacactcaacaccctccagaccaacgccagctacctggagcaggtgaagcgc
cagcggggtgaccctcagacacagctggaagccatggagctgttcttggcacgcagtggg
ctacagttggaggacttggaccagctgaacatcattcatgtcaccgggaccaaggggaag
ggctccacctgtgccttcactgaacgaatcctccgaagctatggcttgaagaccggattc
tttagctctccccacctggtgcaggtgcgcgagcggatccgcatcaacgggcagcccatc
agccctgagctcttcaccaaccacttctggcgcctctaccaccggctgcaggagaccaag
gatggcagcagctgtgtctccatgcccgcctacttccgcttcctcacgctcatggctttc
cacatcttcctccaagagaaggtggacctggcagtggtggaggtgggcatcggtggggct
tacgactgcaccaacatcatcaggaagcctgtggtgtgtggggtctcctctcttggcctc
gaccacaccagccttttgggggacacggtggagaagattgcatggcagaaagggggcatc
ttcaagcgtggtgtccctgccttcaccgtgcttcagcctgacgggcccctggcagtgctg
agggaccgtgcgcagcagatctcatgtcctctctacctgtgcccacctctggaagccctg
gaggaaggggggccaccgctgacccttggcctggagggagagcaccagcggtccaatgct
gccttggccttgcagctggcccgctgctggctgcagcaaaaggaccaccagggcatcggg
gagctgaaggcatcccagccgagtctccagtggcagctgcccctggcacccgtcttccag
cccacgtcccacatgcagcacgggcttcgggacacggagtggcctggccggacgcaggtg
ctgcggcgcgggccgctcacctggtacctggacggcgcgcacaccgtcagcagcgtgcag
gcctgcgtgcgctggttccgccaggcgctgcgcggccgtgacagaccggacagtgggccc
gaggtgcgtgtcttgctcttcaactctactggggaccgggatcccgcggccctgctgaag
ctgttgcagccctgccagtttcactatgctgttttctgccccaacctgacagaggtgtca
cccacgggtaacgaagaccagcagaacttcacagtgacactggaccaggtgctgctccgc
tgcctcacacaccagcagcactggagccgcctggacaaggagcaggccagcccgaacctc
tggaacagccccggcccggagcctggtgggcccgcgtccttgctgctggcaccctgcctg
ccccaccccgtcagcaccagctcccttgtcttcagctgcatctcccacgccttgcagtgg
atcagccaaggccgggaccctgtctttcagccacccagtcccccacggggcctcctcgcc
caccccgtggcaggcagcggggccagtgtactgcgggaggctgctgccatccacgtgctg
gtcacaggcagcctgcacctggtcgggggtgtcctgaagctgctggagccctccctgtcc
cagtag
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