Equus przewalskii (Przewalski's horse): 103547094
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Entry
103547094 CDS
T04644
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
epz
Equus przewalskii (Przewalski's horse)
Pathway
epz00230
Purine metabolism
epz01100
Metabolic pathways
epz04927
Cortisol synthesis and secretion
epz04934
Cushing syndrome
epz05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
epz00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
103547094 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
103547094 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
103547094 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
103547094 (PDE8B)
Enzymes [BR:
epz01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
103547094 (PDE8B)
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GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS_9
PAS
PAS_3
PAS_4
PAS_8
DUF4194
DUF3757
DHH
Motif
Other DBs
NCBI-GeneID:
103547094
NCBI-ProteinID:
XP_070427675
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Position
13:complement(86884850..87102281)
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AA seq
884 aa
AA seq
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MGCAPSIHVSQSGVIYCRDSDESNSPRQTTSVSQGPAAPLHGLFVQTDAADAIPPSRARG
PPGAARVRRARAELGSGSSAGSAAPAATTCRGRRRHCCSSAEAETQTSYTSVQVSSAEVR
IGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEIIV
IDHRQTRNFDAEAVCRSIRATNPSEHTVILAVVSQASGDHEETSVLPLLRAGFNRRFMEN
SSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFERM
MGYHKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVKI
TPVIGQGGKIRHFVSLKKLCCTTDNNKQIHKIHRDSGDNSQTESHSFRYKNRRKESIDVK
SISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLEI
LRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPITIN
DVPPSIAQLLDNEESWEFNIFELEAVTHKRPLVYLGLKVFSRFGVCEVLHCSETTLRAWL
QVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHPG
RTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDSKCNIFKNIDRNHYRTLRQAII
DMVLATEMTKHFEHVNKFVNSINKPLAAEIEGSDCECNPTGKNFPENQILIKRMMIKCAD
VANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFI
TDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq
2655 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccccagcatccacgtctcgcagagcggcgtgatctactgccgggactcg
gacgagtccaactcgccccgccagaccaccagcgtgtcgcagggccccgcggcccccctg
cacggcctcttcgtccagaccgacgccgccgacgccatccccccgagccgcgcgcgcgga
ccccccggcgccgcccgcgtccgcagggcccgcgcggagctgggcagcggcagcagcgcg
ggctcggcggcccccgccgcgaccacctgcaggggccggaggcgccactgctgcagcagc
gcggaggccgagacccagaccagctacaccagcgtccaggtttcttctgcagaggtacgg
attgggcccatgagactgacgcaagatcctattcaggttttgctgatctttgcgaaggag
gatagtcagagtgatggcttctggtgggcctgtgacagagctggttatcggtgcaacatc
gctcggaccccggagtcagcccttgagtgttttctggataaacatcatgagattattgtc
atcgatcatagacaaactcgaaactttgatgcagaagcggtgtgcaggtcgatccgggcc
accaacccctccgagcacacggtgatccttgcggtggtttcacaagcatcgggcgaccat
gaagagacctcagtcctccctcttctgcgtgcaggcttcaacaggagatttatggagaat
agcagcataattgcttgctataacgaactgattcaaatagaacatggggaagttcgctca
cagttcaaattacgggcctgtaattcggtgtttacagcattagaccactgtcatgaagcc
atcgaaataacaagtgatgaccatgtgattcagtatgtcaacccagccttcgaaaggatg
atgggctaccacaaaggggagctcctcgggaaagagctcgccgagctgcccaaaagcgac
aagaaccgggccgaccttctcgacaccatcaatacgtgcatcaagaagggcaaggagtgg
cagggggtttactatgccagacggaaatccggggacagcatccaacagcacgtgaagatc
accccagtgattggccaaggagggaaaattaggcattttgtctccctcaagaaactgtgt
tgcaccaccgacaataacaagcagattcacaagattcatcgggattcaggagacaattct
cagacagagtcccactcattcagatacaagaacaggaggaaagagtccattgacgtgaag
tcgatatcgtctcgaggcagtgatgcaccaagcctacagaatcgtcgctatccatccatg
gcaaggatccattccatgaccatcgaggctcccatcacaaaggttataaatataattaat
gcagcccaagaaaacagccccgtcacagtagcagaagccttggacagagttttagaaatt
ttacggaccacagaactgtactcccctcagctgggtaccaaagatgaagaccctcacacc
agtgatcttgttggaggcctgatgactgacggcttgcgaaggctgtcaggaaacgagtat
gtgttcactaagaacgtgcaccagagtcacagtcacctggcgatgccaataaccatcaac
gatgtccccccttctatcgctcaattactcgataatgaggaaagctgggagttcaacatc
tttgaactggaagctgttacacataaaaggccattggtttacctgggcttaaaggtcttt
tcccggtttggggtatgtgaagttttacactgttctgaaacgacacttcgggcctggctc
caagtgatcgaagccaactaccactcctccaatgcctaccataattccacgcacgccgcc
gacgtcctgcacgccacggccttcttccttgggaaggaaagagtgaagggaagcctcgat
cagctggatgaggtggcagcactgattgcggccacagtccatgacgtggatcacccggga
aggaccaactctttcctgtgtaacgcaggcagtgaacttgctgtactctataatgacacc
gccgtcttggagagtcaccacacagccctggccttccagctcacggtcaaggacagcaaa
tgcaacattttcaagaatattgacaggaaccattatcgaacactgcgccaggctattatt
gacatggttttagcaacggaaatgacaaaacactttgaacatgtgaacaagtttgtgaac
agcatcaacaagccactggcagccgagattgagggcagcgactgtgaatgcaaccctact
gggaagaacttccctgagaaccaaatcctgatcaagcgcatgatgattaagtgcgccgac
gtggccaacccctgccgccccctggacctgtgcatcgaatgggccgggaggatctcggag
gagtatttcgcacagacggacgaagagaagagacaggggctgcccgtggtgatgccagtg
tttgaccggaacacctgcagcatcccgaagtcccagatctccttcattgactacttcata
acagacatgtttgatgcttgggatgcctttgcacacctgccagccctcatgcagcacttg
gccgacaactacaaacactggaagacactggatgacctcaagtgcaaaagcctgaggctt
ccgtctgacagctaa
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