KEGG   Equus przewalskii (Przewalski's horse): 103550364
Entry
103550364         CDS       T04644                                 
Symbol
STAT3
Name
(RefSeq) signal transducer and activator of transcription 3 isoform X1
  KO
K04692  signal transducer and activator of transcription 3
Organism
epz  Equus przewalskii (Przewalski's horse)
Pathway
epz01521  EGFR tyrosine kinase inhibitor resistance
epz04062  Chemokine signaling pathway
epz04066  HIF-1 signaling pathway
epz04068  FoxO signaling pathway
epz04081  Hormone signaling
epz04217  Necroptosis
epz04550  Signaling pathways regulating pluripotency of stem cells
epz04630  JAK-STAT signaling pathway
epz04659  Th17 cell differentiation
epz04917  Prolactin signaling pathway
epz04920  Adipocytokine signaling pathway
epz04931  Insulin resistance
epz04933  AGE-RAGE signaling pathway in diabetic complications
epz04935  Growth hormone synthesis, secretion and action
epz05145  Toxoplasmosis
epz05160  Hepatitis C
epz05161  Hepatitis B
epz05162  Measles
epz05163  Human cytomegalovirus infection
epz05167  Kaposi sarcoma-associated herpesvirus infection
epz05169  Epstein-Barr virus infection
epz05171  Coronavirus disease - COVID-19
epz05200  Pathways in cancer
epz05203  Viral carcinogenesis
epz05205  Proteoglycans in cancer
epz05206  MicroRNAs in cancer
epz05207  Chemical carcinogenesis - receptor activation
epz05212  Pancreatic cancer
epz05221  Acute myeloid leukemia
epz05223  Non-small cell lung cancer
epz05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
epz05321  Inflammatory bowel disease
epz05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:epz00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    103550364 (STAT3)
   04066 HIF-1 signaling pathway
    103550364 (STAT3)
   04068 FoxO signaling pathway
    103550364 (STAT3)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    103550364 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    103550364 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    103550364 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    103550364 (STAT3)
   04062 Chemokine signaling pathway
    103550364 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    103550364 (STAT3)
   04917 Prolactin signaling pathway
    103550364 (STAT3)
   04935 Growth hormone synthesis, secretion and action
    103550364 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103550364 (STAT3)
   05206 MicroRNAs in cancer
    103550364 (STAT3)
   05205 Proteoglycans in cancer
    103550364 (STAT3)
   05207 Chemical carcinogenesis - receptor activation
    103550364 (STAT3)
   05203 Viral carcinogenesis
    103550364 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103550364 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    103550364 (STAT3)
   05221 Acute myeloid leukemia
    103550364 (STAT3)
   05223 Non-small cell lung cancer
    103550364 (STAT3)
  09172 Infectious disease: viral
   05161 Hepatitis B
    103550364 (STAT3)
   05160 Hepatitis C
    103550364 (STAT3)
   05171 Coronavirus disease - COVID-19
    103550364 (STAT3)
   05162 Measles
    103550364 (STAT3)
   05163 Human cytomegalovirus infection
    103550364 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103550364 (STAT3)
   05169 Epstein-Barr virus infection
    103550364 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103550364 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    103550364 (STAT3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103550364 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    103550364 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    103550364 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103550364 (STAT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:epz03000]
    103550364 (STAT3)
Transcription factors [BR:epz03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    103550364 (STAT3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int STAT_linker SH2 E2R135 Baculo_PEP_C
Other DBs
NCBI-GeneID: 103550364
NCBI-ProteinID: XP_008517426
UniProt: A0ABM2ETF9
LinkDB
Position
10:20586062..20648133
AA seq 770 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM
NT seq 2313 nt   +upstreamnt  +downstreamnt
atggcccaatggaatcagctgcagcagctcgacacccggtacctggagcagctccatcag
ctgtacagtgacagcttcccgatggagctgcggcaatttctggccccttggattgagagt
caagattgggcgtatgcggccagcaaagaatcacatgccactttggtgtttcataatctc
ttgggtgagattgaccagcagtacagccgcttcctccaagagtcaaacgtcctctatcag
cacaatctgcgaagaatcaagcagttccttcagagcaggtatctcgagaagccaatggag
attgcccgaattgtggcccgatgcctgtgggaagagtcccgcctcctccagactgcagcc
actgcagcccagcaagggggccaggccaatcaccccaccgcggccgtggtgacggagaag
cagcagatgctggagcagcacctgcaggatgttcggaagcgagtacaggatctagaacag
aaaatgaaagtggtagagaatctccaggatgactttgatttcaactataaaaccctcaag
agtcaaggagacatgcaggatctgaatggaaacaaccagtcagtgaccaggcagaagatg
cagcagctggaacagatgcttactgcgctggaccagatgcggcgaagcatcgtgagtgag
ttggcggggcttctgtcagctatggagtatgtgcagaagactctcacggatgaagagctg
gctgactggaagaggcgacaacagattgcttgcatcggaggccctcccaacatctgccta
gatcgtctagaaaactggataacctcattagcagaatctcaacttcagacccgccaacaa
attaagaaactggaggagttgcagcagaaagtttcctataaaggagaccccatcgtacag
caccggcccatgctcgaggagagaattgtggagctgtttagaaacttaatgaaaagtgcc
tttgtggttgagcggcagccctgcatgcccatgcatcccgaccggcccttagtcatcaag
accggtgtccagtttactactaaagtcagattgctggtcaaatttccggaattaaattat
cagcttaaaattaaagtgtgcattgacaaagactccggggacgttgcagctctcagagga
tcccggaaatttaacattctgggcacaaacacaaaagtgatgaacatggaagagtccaac
aacggcagcctctctgcagagttcaaacacttgaccctgagagagcaaagatgtggtaac
gggggccgagccaattgtgacgcctccctgattgtgaccgaggagctgcacctgatcacc
tttgagactgaagtgtatcaccaaggcctcaagattgaccttgagacccactccctgcca
gttgtggtgatctccaacatctgtcagatgccaaatgcctgggcctcaatcttgtggtat
aacatgctgaccaacaaccccaagaacgtgaactttttcaccaagcccccaattggaacc
tgggatcaagtggccgaggtgctgagctggcagttctcctccaccaccaagcggggactg
agcatcgagcagttgaccacgctggcagagaaactcttagggccgggtgtgaactattca
gggtgtcagatcacgtgggctaaattttgcaaagaaaacatggctggcaagggcttctcc
ttctgggtctggctggacaatatcattgatcttgtgaaaaagtacatcctggccctctgg
aatgaagggtacataatgggctttatcagtaaggagcgggagcgggccatcttgagcacc
aagcccccaggcaccttcctgctgagattcagtgaaagcagcaaagaaggaggcgtcacc
ttcacttgggtggagaaggacatcagcggtaagactcagatccagtcagtagaaccatat
accaagcagcagctgaacaacatgtcgtttgctgagatcatcatgggctacaagatcatg
gatgccaccaatatcctggtgtctccgctggtctatctctaccccgacattccaaaggag
gaggccttcggaaagtactgtcggccagagagccaggagcatcctgaagccgacccaggt
agtgctgccccatacctgaagaccaagtttatctgtgtgacaccaacgacctgcagtaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataat
ggtgaaggtgctgagccctcagcaggagggcagtttgagtccctcacattcgacatggag
ttgacctcggagtgcgctacctcccccatgtga

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