Equus przewalskii (Przewalski's horse): 103553259
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Entry
103553259 CDS
T04644
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
epz
Equus przewalskii (Przewalski's horse)
Pathway
epz00270
Cysteine and methionine metabolism
epz00480
Glutathione metabolism
epz01100
Metabolic pathways
epz01240
Biosynthesis of cofactors
epz04216
Ferroptosis
Module
epz_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
epz00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
103553259 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
103553259 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
103553259 (GCLC)
Enzymes [BR:
epz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
103553259 (GCLC)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
103553259
NCBI-ProteinID:
XP_070440902
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Position
19:complement(51251398..51295927)
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AA seq
637 aa
AA seq
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MGLLSQGSPLSWEETQRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKRVQLILSGEEILETLQEQGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSLLEGHQALCTITSFPRLGCPGFTLPEFKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDDEAAKASKPDHVYMDA
MGFGMGNCCLQVTFQACSIAEARYLYDQLATICPIVMALSAASPFYRGHVSDIDCRWGVI
SASVDDRTREERGLEPLKKNKYRISKSRYDSIDSYLSECGEKYNDIDLTIDKEIYEQLLR
EGLDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
QEMFYFRKDICKGGNAVVDGCGKAQSSTELATEEYTLMSINTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYS
LIFKCNQIANELCECPELLGPAFRKVKYSGSKTESSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccagggctcgccgctgagctgggaggagacccagcggcacgccgac
cacgtgcggcggcacggcatcctccagttcctgcacatctaccacgctgtcaaggaccgg
cacaaggacgtgctcaagtggggcgacgaggtggaatacatgttggtatcttttgatcat
gaaaataaaagagtccagttgatcctgtctggagaggaaattctcgaaactctgcaagaa
cagggggagaggacaaacccaaaccatcctaccctttggagaccagagtacgggagttat
atgattgaagggacccccggacagccgtacggaggaacgatgtccgagttcaacacagtt
gaagacaacatgcgcaaacgccggaaggaggccacttcgctattagaaggccatcaggct
ctttgcacaattacttcctttcccagattaggctgtcctgggtttacgctgcccgagttc
aaacccaacccggtcgaaggaggagcttccaagtccctcttctttcccgatgaagccata
aacaagcacccccgcttcagtaccctaacaagaaacatccgacataggagaggagaaaag
gtcgtcatcaatgtaccaatatttaaggacaagaatacaccatctccatttatagaaacg
tttcccgaggatgatgaggcagcgaaggcttctaagcccgatcacgtttacatggacgcc
atgggatttgggatgggcaactgctgccttcaggtaacattccaagcctgcagcatagct
gaggccagatacctttatgatcagttggccaccatctgcccaattgtcatggctttgagc
gctgcgtctcctttttaccgaggccacgtgtcagacattgattgtcgctggggagtgatc
tctgcgtctgtagatgatagaactcgggaggagagaggcctggagccactgaagaaaaat
aagtataggattagtaaatcccggtatgattcaatagacagttatttatctgaatgtggt
gagaaatataatgacatcgacttgacaatagataaagaaatctatgaacagctgttacgg
gaaggccttgaccacctcctggcccagcatgttgctcatctcttcatcagagacccactg
actctgtttgaagagaaaatacacctggacgatgccaacgagtctgaccatttcgagaat
attcagtccacaaattggcagacaatgaggtttaagccccctcctccaaactcggatatc
ggatggcgagtagaattccgacccatggaggttcagctgacggactttgagaactccgcg
tacgtggtgtttgtggtgctgctcaccagggtgatcctgtcgtacaagctggattttctc
atcccgctgtcaaaggttgatgaaaacatgaaagtcgcacagaaacgggatgctgtcttg
caggaaatgttttatttcaggaaagatatttgcaaaggtggcaacgccgtggtggatggc
tgtgggaaggctcagagcagcacggagctggccacggaggagtacacgctgatgagcatc
aacaccatcatcaacgggaaggaaggtgtgtttcctgggctgatcccgattctgaactcg
taccttgaaaacatggaagtggatgtggacaccagatgtagcattctgaactacctaaag
ctgattaagaagagagcatctggagaactaatgacagttgccagatggatgagggagttt
atcgcgaaccatcctgactacaagcaagacagtgtgataaccgacgaaatgaactatagc
cttattttcaagtgtaaccaaattgcaaatgaattatgtgaatgcccagagctactcgga
ccagcatttaggaaagtaaaatatagcggaagcaaaactgagtcttccaactag
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