Equus przewalskii (Przewalski's horse): 103554269
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Entry
103554269 CDS
T04644
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
epz
Equus przewalskii (Przewalski's horse)
Pathway
epz01521
EGFR tyrosine kinase inhibitor resistance
epz04062
Chemokine signaling pathway
epz04081
Hormone signaling
epz04148
Efferocytosis
epz04151
PI3K-Akt signaling pathway
epz04217
Necroptosis
epz04550
Signaling pathways regulating pluripotency of stem cells
epz04630
JAK-STAT signaling pathway
epz04658
Th1 and Th2 cell differentiation
epz04659
Th17 cell differentiation
epz04725
Cholinergic synapse
epz04917
Prolactin signaling pathway
epz04920
Adipocytokine signaling pathway
epz04933
AGE-RAGE signaling pathway in diabetic complications
epz04935
Growth hormone synthesis, secretion and action
epz05140
Leishmaniasis
epz05145
Toxoplasmosis
epz05152
Tuberculosis
epz05161
Hepatitis B
epz05164
Influenza A
epz05167
Kaposi sarcoma-associated herpesvirus infection
epz05168
Herpes simplex virus 1 infection
epz05200
Pathways in cancer
epz05207
Chemical carcinogenesis - receptor activation
epz05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
epz05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
epz00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
103554269 (JAK2)
04151 PI3K-Akt signaling pathway
103554269 (JAK2)
09133 Signaling molecules and interaction
04081 Hormone signaling
103554269 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
103554269 (JAK2)
09143 Cell growth and death
04217 Necroptosis
103554269 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
103554269 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
103554269 (JAK2)
04659 Th17 cell differentiation
103554269 (JAK2)
04062 Chemokine signaling pathway
103554269 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
103554269 (JAK2)
04917 Prolactin signaling pathway
103554269 (JAK2)
04935 Growth hormone synthesis, secretion and action
103554269 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
103554269 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103554269 (JAK2)
05207 Chemical carcinogenesis - receptor activation
103554269 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
103554269 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
103554269 (JAK2)
05164 Influenza A
103554269 (JAK2)
05168 Herpes simplex virus 1 infection
103554269 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
103554269 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
103554269 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
103554269 (JAK2)
05140 Leishmaniasis
103554269 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
103554269 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
103554269 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103554269 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
epz01001
]
103554269 (JAK2)
Enzymes [BR:
epz01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
103554269 (JAK2)
Protein kinases [BR:
epz01001
]
Non-receptor tyrosine kinases
JAK family [OT]
103554269 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
Kdo
ABC1
RIO1
FERM_C_FAK1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
103554269
NCBI-ProteinID:
XP_008523468
LinkDB
All DBs
Position
22:24763014..24899300
Genome browser
AA seq
1131 aa
AA seq
DB search
MGMACLTMAEMEGTSVSVHQNGDIPGNANSVKQVDPVLQVYLYHSLEKAEGDYLKFPTGE
YVAEEICVAASKACGITPVYHSMFALMSETERIWYPPNHVFHIDESARHSVLYRIRFYFP
YWYCNGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFLHGWVKVPVTHETQEECLGM
AVLDMMRIAKEKDQTPLTIYSSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQFS
HCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSRG
KHKESETLTEQNLQLYCDFPDIIDVNIKQAHQEGSNESRIVTIHKQDGKTLEIELSSLRE
ALSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPISMDFAISKLKKAGNQTG
LYVLRCSPKDFNKYFLTFAVERENVIEHKHCLITKNENGEYNLSGTKKNFSSLKDLLNCY
QMETVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGVSEVPTSPTLQRHNNVNQMVFHKIR
NEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKSHRNYSESFFEAASMM
SQLSHKYLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWAM
HFLEEKTLIHGNVCAKNILLTREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPP
ECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTELA
NLINSCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDP
TQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEI
LKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQIC
KGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWY
APESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIEL
LKNNGRLPKPDGCPDEIYVIMTQCWNNNVNQRPSFRDLALRVDQIRDNMAG
NT seq
3396 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcttgccttacaatggcagaaatggaaggaacatctgtgtctgtgcatcag
aatggtgatattcctggaaatgctaattctgtaaagcaagtagatccagtcctacaggtg
tatctttatcattcccttgagaaagctgaaggagattacctgaagtttccaactggggag
tatgttgcggaagaaatttgtgttgctgcttctaaagcttgcggaatcacacctgtgtat
cacagtatgttcgctttaatgagtgaaacagaaagaatctggtatccccccaaccatgtc
ttccatatagatgaatcagccaggcacagtgtactctacagaataagattttactttcct
tactggtattgtaatggcagcaacagaacctatcggcatggaatatctcgaggtgctgaa
gctcctcttcttgatgactttgtcatgtcttacctttttgctcagtggcggcatgacttt
ttgcatggatgggtaaaagtacctgtgactcatgaaacacaggaagaatgtcttgggatg
gcagtgttagatatgatgagaatagccaaagaaaaggatcaaaccccactgaccatctat
agctctatcagctacaagacattcttaccaaaatgtgttcgagcaaagatccaagactat
catattttgacaaggaaacgaataaggtacagatttcgcagatttattgagcaattcagc
cattgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaactctt
cagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttcaggt
gaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaagaggg
aaacataaagaaagtgagacactgacagaacagaatttacagttatattgtgattttcct
gatattattgatgtgaatattaagcaagcacaccaagaaggctcaaatgaaagcagaatt
gtaactatccataagcaagatggtaaaactctggaaattgaacttagctcattgagagaa
gctttgtcttttgtgtcattaattgatggatattatagattaactgcagatgcacatcat
tacctctgtaaagaagtagcacctccaatggtgcttgaaaatatacaaagcaactgtcat
ggcccaatttcaatggattttgccatcagcaagctgaagaaagcaggtaatcaaactgga
ctctatgtacttcgatgcagtcctaaggactttaataaatattttctgacttttgctgtc
gagcgagaaaatgtcattgaacataagcactgtttgattacaaaaaatgagaatggagaa
tacaacctaagtgggactaagaagaacttcagtagtcttaaagatcttttgaattgctat
cagatggaaactgttcgctcagacagtataattttccagtttactaaatgctgtccccca
aagccaaaagataaatcaaaccttctagtcttcagaaccaatggtgtttctgaggtaccg
acctcaccaacattacagaggcataataatgtgaaccaaatggtgtttcacaaaatcaga
aatgaagatttgatatttaatgaaagccttggccaaggcacttttacaaaaatttttaaa
ggtgtaagaagagaagtaggagactatggtcaactgcatgaaacagaagttcttttgaaa
gttctggataaatcacatagaaactactcagagtctttctttgaagcagcaagcatgatg
agccagctttctcacaaatatctggttttaaattatggagtgtgtgtctgtggagaggag
aatattctggttcaggagtttgtaaaatttggatcactagatacatatctgaaaaagaat
aaaaattctataaatatattatggaaacttgaagtagctaaacagttggcatgggccatg
cattttctagaagaaaaaacccttattcatgggaatgtgtgtgccaaaaatattctactt
accagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcctggc
attagtattacagttttgccaaaagacattcttcaggagagaataccatgggtaccacct
gaatgcattgaaaatcctaaaaatctaaacttggcaacagacaaatggagttttggtacc
actttgtgggaaatttgcagtggaggagataagcctctgagtgctttggattctcaaaga
aagctacagttttatgaagataggcaccagcttcctgcaccaaagtggacagaattagca
aatcttatcaatagttgtatggattacgaaccagattttagaccttctttcagagccatc
atacgtgatcttaatagtttgtttactccagattatgagctgttaacagaaaatgacatg
ttaccaaatatgaggataggtgccctagggttttctggtgctttcgaagaccgagaccct
acgcagtttgaagagagacacttgaaatttctacagcaacttggcaagggtaattttggg
agtgtggagatgtgccgttatgaccctctacaagacaacactggggaggtggtggctgtg
aaaaagctccagcacagtactgaagagcacctcagagactttgaaagggaaattgaaatc
cttaaatccctgcagcatgacaacattgtaaagtacaagggagtgtgctacagtgctggc
cggcgtaatctaagattaattatggaatatttaccatatggaagtttacgagactatctc
caaaaacataaagaacggatagatcataaaaaacttctgcagtacacatctcagatatgc
aagggtatggaatatcttggtacaaaaagatatatccacagggatctggcaacaaggaat
atattggtggaaaatgaaaacagagttaaaattggagattttgggttaaccaaagtcttg
ccacaagacaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctggtat
gctccagaatcactgacagagagcaagttttctgtggcctcagatgtttggagctttgga
gtggttctgtatgaactttttacatatattgagaagagtaaaagtccaccagcggaattt
atgcgtatgattggcaatgacaaacaaggacagatgattgtgtttcatttgatagaactc
ctgaagaataatggaagattaccaaaaccagatggatgcccagatgagatttatgtgatc
atgacacaatgctggaacaacaatgtaaatcagcgcccctctttcagagacctagctctt
cgagttgatcaaataagggacaacatggctggatga
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