Equus przewalskii (Przewalski's horse): 103558137
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Entry
103558137 CDS
T04644
Symbol
CYP17A1
Name
(RefSeq) steroid 17-alpha-hydroxylase/17,20 lyase
KO
K00512
steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:
1.14.14.19
1.14.14.32
]
Organism
epz
Equus przewalskii (Przewalski's horse)
Pathway
epz00140
Steroid hormone biosynthesis
epz01100
Metabolic pathways
epz04913
Ovarian steroidogenesis
epz04917
Prolactin signaling pathway
epz04927
Cortisol synthesis and secretion
epz04934
Cushing syndrome
Module
epz_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
epz_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
epz_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
epz_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
epz00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
103558137 (CYP17A1)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
103558137 (CYP17A1)
04917 Prolactin signaling pathway
103558137 (CYP17A1)
04927 Cortisol synthesis and secretion
103558137 (CYP17A1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
103558137 (CYP17A1)
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:
epz00199
]
103558137 (CYP17A1)
Enzymes [BR:
epz01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.19 steroid 17alpha-monooxygenase
103558137 (CYP17A1)
1.14.14.32 17alpha-hydroxyprogesterone deacetylase
103558137 (CYP17A1)
Cytochrome P450 [BR:
epz00199
]
Cytochrome P450, animal type
CYP17 family
103558137 (CYP17A1)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
p450
Motif
Other DBs
NCBI-GeneID:
103558137
NCBI-ProteinID:
XP_008529170
LinkDB
All DBs
Position
1:27419931..27429758
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AA seq
508 aa
AA seq
DB search
MWELLAFLLLAIAYFFRPKVKCPGAKYPKSLPYLPLVGSLPFLPRHGHPHVNFFKLQKKY
GPIYSLRMGTKTTVMVGHYQLAKEVLIKKGKEFSGRPQVATLNILSDNQKGVAFADHGAP
WQLHRKLVRAAFALFKDGNQKLEKIICHETSLLCDLLATQNGQTIDLSSPLFLAVTNVIC
WICFNSSYMKGDPALETMQNYHKGILETLEKDNVVDIFPALKIFPNKSLEKMRHCVNIRN
ELLSKIFEKHKENFNSDSITSMLDLLIQAKKNSDNNNTGPDQDSKLLSDKHILATIGDIF
GAGVETTTSVVKWIVAFLLHDPQLKKKIQEEIDQNVGFSRTPTLSDRNRLLLLEATIREV
LRIRPVAPMLIPHKALVDSSIGEFAVDEGTNVIINLWALHHNEKEWHQPDRFMPERFLDP
TGSQLISPSLSYLPFGAGPRSCIGELLARQELFLFTAWLLQRFNLEVPDDGQLPSLEGHP
TAVFLIDSFKVKINVRQAWREAQAEGST
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atgtgggagctcttggctttcctgctgttggccatagcctatttctttcggcccaaggtt
aagtgccctggtgccaagtaccccaagagcctcccatacctgcccttggtgggcagcctg
ccgttccttcccagacatggccatccgcatgtgaacttcttcaagctgcagaaaaaatac
ggccccatctattccttgcgcatgggtaccaagactacggtgatggtcggccactaccaa
ctggccaaggaggtgcttatcaagaagggcaaggaattctccgggcggccccaagtggca
actctaaacatcctgtcagacaatcaaaagggtgtcgccttcgccgaccatggtgccccc
tggcagctgcatcggaagctggtgcgggctgcttttgccctgttcaaggacggcaaccag
aagctggagaagattatatgtcatgaaaccagtttattgtgtgacttactggccactcag
aatggacagaccatagacttgtcctcgcctctcttcctggcggtgaccaacgtaatctgc
tggatctgcttcaactcctcctacatgaaaggggatcctgcgctggagaccatgcagaat
taccacaaaggcatcctggagactctggaaaaagacaatgtggtagacatattccccgca
ttgaagattttccccaacaaatccctggaaaaaatgaggcattgtgttaacatacgaaat
gaactgctgagtaaaatctttgaaaaacataaggagaacttcaacagtgactccatcact
agcatgctggacttactgatccaagccaagaagaactcagacaataacaacactggccca
gaccaggattcaaagctgctttcggataaacacattcttgccaccataggggacatcttc
ggggccggtgtggagaccaccacctctgtggtgaagtggattgtggccttcctgctgcac
gaccctcagctgaagaagaagatccaggaggagattgaccagaatgtgggtttcagccgc
acaccaacactcagtgaccggaaccgcctccttctgctggaggccaccatccgagaagtg
cttcgtatccggcctgtggcccctatgctcatcccccataaggctcttgttgactccagc
atcggcgagtttgctgttgacgagggcacaaacgtcatcatcaatttgtgggcactccat
cacaatgagaaggagtggcaccagcctgaccggttcatgcctgagcgcttcttggaccca
acggggagccagctcatctcaccgtcgttaagctacttgccctttggagcaggtccccgc
tcttgcataggtgagctcctggcccgccaggagctcttcctcttcacggcctggttgctg
cagaggtttaacctggaggtcccggatgatggccagctgccctccctggagggccacccc
acagcggtctttctgatcgactctttcaaagtgaagattaatgtgcgccaggcctggagg
gaggcccaggctgagggcagcacctag
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