Equus przewalskii (Przewalski's horse): 103558215
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Entry
103558215 CDS
T04644
Symbol
HSD17B2
Name
(RefSeq) 17-beta-hydroxysteroid dehydrogenase type 2 isoform X1
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
epz
Equus przewalskii (Przewalski's horse)
Pathway
epz00140
Steroid hormone biosynthesis
epz01100
Metabolic pathways
epz04913
Ovarian steroidogenesis
Module
epz_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
epz00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
103558215 (HSD17B2)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
103558215 (HSD17B2)
Enzymes [BR:
epz01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
103558215 (HSD17B2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
103558215 (HSD17B2)
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Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
Epimerase
IcmF-related
NmrA
Motif
Other DBs
NCBI-GeneID:
103558215
NCBI-ProteinID:
XP_008529294
UniProt:
A0ABM2F465
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Position
3:29478759..29541558
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AA seq
384 aa
AA seq
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MSLFCSETVGLCLAVTVVLGGAVLCKLKSPGQEGRKVVCLVGLWGGACLLSLSLFWGLLL
FSLSCCLMYTYLSGQELLPVDQKAVLITGSDSGIGHALSKHLDELGFTVFAGVLDAKGSG
AEELRRSCSKRLSVLQLDITDPQQIKDAYSKVLEKVQNRGLWAVVNNAGIICFPAEGELI
PMTHYKRCMAVNFFGAVEVTKAFLPLLRRSKGRLVSISSMAAGVPMEKLAAYGSSKAALT
MFSAVMRRELSKWGIKVSVIQPGGFQTNIAGTSEMQDKLEKNLLDHLTPDVQEDYGQDYI
LAERNFLSVLNVKSQPDVSPVLRDIRHAISAKSPFAFYAPGKESYLFLCFASFVPTCVFD
LFLKNDGQSMPRALRMPNWKNKAM
NT seq
1155 nt
NT seq
+upstream
nt +downstream
nt
atgagtcttttctgctctgagacagtggggctctgcctggctgtcaccgtagtgctggga
ggagcagttctttgcaaactgaagagcccagggcaggaggggagaaaggtggtctgcttg
gtgggcctgtggggaggggcttgcctgctcagcctgtccctcttctggggcttgcttctc
ttctccctgtcatgttgcctcatgtatacttacttatccggccaagagctgttacctgtg
gatcaaaaggcggtgctgatcacaggtagcgattctgggattggccatgctttgtctaag
catctggatgagctgggcttcacagtatttgccggagttctggatgcaaagggatcagga
gcggaggaattacgaagaagctgctccaagcgcctgtctgtgctccagttggacatcact
gacccgcagcagatcaaagacgcctacagcaaagtcctggagaaggtgcagaacagagga
ctgtgggctgtggtcaacaatgctgggatcatttgcttcccagccgagggggagctcatc
cccatgacccactacaaacgatgcatggctgtgaacttctttggggcagtggaagtcacg
aaggcatttttgcctcttcttaggagatccaaagggaggctggtgagcatcagcagcatg
gcagcaggggtcccaatggaaaagctggcagcttatgggtcatccaaggcggctctgacc
atgttttcggcagtcatgagacgagaactttccaaatggggaattaaagtctctgtcatc
cagcccggaggcttccaaacaaatatcgcaggcacgagtgaaatgcaggacaagctggag
aagaacctcttggaccacctcaccccggacgtgcaggaagactacggccaggactatatc
ctcgcagaacggaattttctcagtgtattgaacgtgaagtctcaaccagatgtctccccg
gtgctccgggacatccggcacgccatctccgctaaaagccccttcgccttttacgcaccg
gggaaggagtcttatctgttcctctgttttgcttcctttgtccctacttgcgtatttgat
ctttttctcaagaacgatggacagagcatgcccagagctctaaggatgcctaactggaag
aataaggccatgtag
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