KEGG   Equus przewalskii (Przewalski's horse): 103567795
Entry
103567795         CDS       T04644                                 
Symbol
MAP2K4
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4 isoform X1
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
epz  Equus przewalskii (Przewalski's horse)
Pathway
epz04010  MAPK signaling pathway
epz04012  ErbB signaling pathway
epz04620  Toll-like receptor signaling pathway
epz04664  Fc epsilon RI signaling pathway
epz04668  TNF signaling pathway
epz04912  GnRH signaling pathway
epz04926  Relaxin signaling pathway
epz04935  Growth hormone synthesis, secretion and action
epz04936  Alcoholic liver disease
epz05132  Salmonella infection
epz05135  Yersinia infection
epz05142  Chagas disease
epz05161  Hepatitis B
epz05166  Human T-cell leukemia virus 1 infection
epz05167  Kaposi sarcoma-associated herpesvirus infection
epz05169  Epstein-Barr virus infection
epz05208  Chemical carcinogenesis - reactive oxygen species
epz05417  Lipid and atherosclerosis
epz05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:epz00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103567795 (MAP2K4)
   04012 ErbB signaling pathway
    103567795 (MAP2K4)
   04668 TNF signaling pathway
    103567795 (MAP2K4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    103567795 (MAP2K4)
   04664 Fc epsilon RI signaling pathway
    103567795 (MAP2K4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103567795 (MAP2K4)
   04926 Relaxin signaling pathway
    103567795 (MAP2K4)
   04935 Growth hormone synthesis, secretion and action
    103567795 (MAP2K4)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    103567795 (MAP2K4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103567795 (MAP2K4)
   05161 Hepatitis B
    103567795 (MAP2K4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103567795 (MAP2K4)
   05169 Epstein-Barr virus infection
    103567795 (MAP2K4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103567795 (MAP2K4)
   05135 Yersinia infection
    103567795 (MAP2K4)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    103567795 (MAP2K4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103567795 (MAP2K4)
   05418 Fluid shear stress and atherosclerosis
    103567795 (MAP2K4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103567795 (MAP2K4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:epz01001]
    103567795 (MAP2K4)
Enzymes [BR:epz01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     103567795 (MAP2K4)
Protein kinases [BR:epz01001]
 Serine/threonine kinases: STE group
  STE7 family
   103567795 (MAP2K4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Pkinase_fungal Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 103567795
NCBI-ProteinID: XP_070417214
UniProt: A0ABM4JMP4
LinkDB
Position
10:54235259..54368117
AA seq 410 aa
MAAPSPSGGGGSGGGSGSGTPGPAGSPAPGHPAVSSMQGFQINFCEKAQSKRKALKLNFA
NPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIG
RGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALF
REGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRD
IKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSD
VWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLT
KDESKRPKYKELLKHPFILMYEERTVEVACYVCKILDQMPATPSSPMYVD
NT seq 1233 nt   +upstreamnt  +downstreamnt
atggcggctccgagcccgagcggcggcggcggctccgggggcggcagcggcagcggcacc
ccgggccccgcagggtccccggcgccgggccacccggccgtcagcagcatgcagggcttt
cagataaacttctgtgaaaaggcacaaagtaaacgcaaagcactgaagttgaattttgca
aatccacctttcaaatctacagcaaggtttactctgaatcccaatcctacaggagttcaa
aacccacacatagagagactgagaacacacagcattgaatcgtcaggaaaactgaagatc
tcccctgaacaacactgggatttcactgcagaggacttgaaagaccttggagaaattgga
cgaggagcttatggttccgtcaacaaaatggtccacaaaccaagtgggcaaataatggca
gttaaaagaattcggtcaacagtggatgaaaaagaacaaaaacaacttctcatggatttg
gatgtagtaatgcggagtagtgattgcccatacattgttcaattttatggtgcactcttc
agagagggtgactgttggatctgtatggaactcatgtctacctcgtttgataagttttac
aaatatgtatatagtgtattagatgatgttattccagaagaaattttaggcaaaatcact
ttagcaactgtgaaggctctaaaccacttaaaggaaaacttgaaaatcattcacagagat
atcaaaccttccaatattcttctggacagaagtggaaatattaaactctgtgactttggc
atcagtggacagcttgtggactccattgccaagacaagagatgctgggtgtagaccatac
atggcacctgaaagaatagacccaagtgcgtcgcgacaaggatatgatgtccgctctgac
gtctggagtttggggatcacattgtacgagttggccacgggccgatttccttatccaaag
tggaatagtgtatttgatcaactaacacaagtcgtaaaaggagatcctccacagctgagc
aattctgaggaaagagaattctccccaagtttcatcaactttgtcaacttgtgccttaca
aaggatgaatccaaaaggccaaagtataaagaacttctgaaacatccctttattttgatg
tatgaagaacgtaccgtagaggtcgcatgctatgtttgtaaaatcctggatcaaatgcca
gctactcccagctctcccatgtatgtcgattga

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