KEGG   Erysipelotrichaceae bacterium I46: A4V01_07170
Entry
A4V01_07170       CDS       T04439                                 
Name
(GenBank) D-alanine--D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
erb  Erysipelotrichaceae bacterium I46
Pathway
erb00470  D-Amino acid metabolism
erb00550  Peptidoglycan biosynthesis
erb01100  Metabolic pathways
erb01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:erb00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    A4V01_07170
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    A4V01_07170
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    A4V01_07170
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:erb01011]
    A4V01_07170
Enzymes [BR:erb01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     A4V01_07170
Peptidoglycan biosynthesis and degradation proteins [BR:erb01011]
 Precursor biosynthesis
  Amino acid ligase
   A4V01_07170
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N CPSase_L_D2 ATP-grasp ATP-grasp_3 ATPgrasp_ST GARS_A ATP-grasp_4
Other DBs
NCBI-ProteinID: ANU68730
UniProt: A0A1C7HML5
LinkDB
Position
1473372..1474526
AA seq 384 aa
MKLKIAVAFGGRSVEHEISVLSAQQVMAALDEERYEILPLYIAKDGRMFCEEELRELETF
QHIEEFIADHTSVALIRRDAHTYLIPSRRKLFARDKEVDLVFPVLHGTNGEDGTFQGYLK
TIGIPYVGCSVLAGAIGQDKVIMKQVLQDSGLSVVPWFFWTLHQPMEQSFFKKAQRLGYP
LIIKPANLGSSVGIAVAHNDVELHKSMIEAFQYDHKVVIEKVIEPLREINASVLGDEDGC
RCSTLEEVVKQDEILSYDNKYSGQGKSKGMLSTSRKLPAELSDEQAEEVRTMAMDAFRAL
NAAGVVRIDFLMHADSSALYVNEINTIPGSLSFYLWEKEGLSFPALLDELISLALQRVRR
EQKMIFSYDTNILRDYKGKGKLMK
NT seq 1155 nt   +upstreamnt  +downstreamnt
atgaaacttaaaattgccgtggcatttggcggcagaagtgtagaacatgaaatcagtgtc
ctgtcagctcagcaggtaatggctgctctggatgaggagcgctatgaaatactgccgttg
tatattgccaaggatggcagaatgttttgtgaggaggaattacgggagctggaaaccttt
cagcatattgaagaattcatagcggatcataccagtgtagctctgattcgaagagatgcg
catacctacttgattccatcgcgtcgtaaattatttgccagggataaggaggttgatctg
gtgttcccggttctgcatggaacaaacggagaagacggcacctttcagggatatctgaaa
acgatcgggataccctatgtcggctgcagtgttctggcaggcgcaatcggacaggataag
gtgattatgaaacaggtattgcaggatagcgggctttcggttgtaccgtggtttttctgg
acattgcatcagccgatggagcagtcctttttcaaaaaagcgcagcgtcttggttatccg
ctcatcattaagcctgcgaatctgggcagcagtgtcggcatcgccgttgcccacaatgat
gtggagctgcataaaagcatgatcgaggcctttcagtatgatcacaaggttgtgattgaa
aaggtgattgaaccgctgcgggaaatcaacgcctcggtactgggggatgaggacggctgt
cgctgcagtacactggaagaagttgtcaagcaggatgaaattctgtcttatgacaacaag
tacagcggacagggaaaatccaagggaatgctcagtaccagccggaagctgccggcagag
cttagtgatgagcaggctgaggaggttcgcacgatggcgatggatgccttccgtgcgctg
aatgcggcaggggttgtgcggattgattttctgatgcatgcagacagttcagctctgtat
gtgaatgaaatcaatacgattcctggctccctgtccttctatttgtgggaaaaggaaggt
ctttcctttcctgccctgctggatgagctgatctcgctagcacttcagcgggtacgcagg
gaacagaagatgattttcagctatgacacaaatattctgcgggattataagggcaaagga
aaactgatgaagtag

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