Eulemur rufifrons (Bennett's brown lemur): 138381461
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Entry
138381461 CDS
T11398
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
eruf Eulemur rufifrons (Bennett's brown lemur)
Pathway
eruf00020
Citrate cycle (TCA cycle)
eruf00480
Glutathione metabolism
eruf01100
Metabolic pathways
eruf01200
Carbon metabolism
eruf01210
2-Oxocarboxylic acid metabolism
eruf01230
Biosynthesis of amino acids
eruf04146
Peroxisome
eruf05230
Central carbon metabolism in cancer
Module
eruf_M00009
Citrate cycle (TCA cycle, Krebs cycle)
eruf_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
eruf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
138381461 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
138381461 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
138381461 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
138381461 (IDH2)
Enzymes [BR:
eruf01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
138381461 (IDH2)
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NCBI-GeneID:
138381461
NCBI-ProteinID:
XP_069321816
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Position
3:5848550..5862608
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AA seq
452 aa
AA seq
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MAGYLRAARSLCRAPGPGPAWAPAALTAPAAREQPRRHYADKRIKVAKPVVEMDGDEMTR
IIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYHVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK
ATDFVADRAGTFKMVFTPKDGSSAKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI
QKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTDFDKNKIWYEHRLIDDMVAQVLKS
AGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGSQDLIRFAQTLEKVCVETVESGAMTKDLAGCIH
GLSNVKLNEHFLNTTDFLDTIKSNLDRALGKP
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atggccggctacctgcgggccgcgcgctcgctctgcagagccccgggcccgggcccggcc
tgggcgccggcggccctgacagcccccgccgcgcgagagcagccgcggcgccactatgct
gacaagaggatcaaagtggcgaagccggtggtggagatggacggtgatgagatgacccgg
atcatctggcagttcatcaaggagaagctcatcctgccccacgtggatgtccagctcaag
tattttgaccttgggctcccaaaccgtgaccagaccaacgaccaggtcaccatcgactct
gcgttggccacccagaagtaccacgtggctgtcaagtgtgccaccatcacccccgatgag
gcccgcgtggaagagttcaaactgaagaagatgtggaaaagtcccaatggaaccatccgg
aacatccttggggggactgtcttccgggagcccatcatctgcaagaacatcccacgcctc
gtgcctggctggaccaagcctatcaccattggcaggcatgcccacggcgaccagtacaag
gccacagacttcgtggcggatcgcgccggcacgttcaagatggtcttcaccccgaaggat
ggcagcagtgccaaggagtgggaggtgtacaacttccccgcgggcggcgtgggcatgggc
atgtacaacaccgacgagtccatctcgggctttgcgcacagctgcttccagtatgccatc
cagaagaagtggccgctgtacatgagcaccaagaacaccattctgaaagcctacgacggg
cgtttcaaggacatcttccaggagatctttgagaagcattataagacggacttcgacaag
aataagatctggtatgagcaccggctcattgacgacatggtggctcaggtcctcaagtct
gcgggcggcttcgtgtgggcttgcaagaactacgacggagacgtgcagtcagatatcctg
gcccagggcttcggctccctgggcctgatgacgtctgtgctggtctgcccggatgggaag
accattgaggccgaggcggctcacgggacggtcacccgccactatcgggagcaccagaag
ggccggccaaccagcaccaaccccatcgccagcatcttcgcctggacgcgcggcctggag
caccggggcaagctggacgggagccaggacctcatcaggtttgcccagaccctggagaag
gtgtgcgtcgagacggtggagagtggggccatgaccaaggacctggcgggctgcatccac
ggcctcagcaacgtgaagctgaacgagcacttcctgaacaccacggacttcctggacacc
atcaagagcaacctggacagagccctgggcaagccgtag
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