Eulemur rufifrons (Bennett's brown lemur): 138381495
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Entry
138381495 CDS
T11398
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
eruf Eulemur rufifrons (Bennett's brown lemur)
Pathway
eruf01521
EGFR tyrosine kinase inhibitor resistance
eruf01522
Endocrine resistance
eruf04010
MAPK signaling pathway
eruf04014
Ras signaling pathway
eruf04015
Rap1 signaling pathway
eruf04066
HIF-1 signaling pathway
eruf04068
FoxO signaling pathway
eruf04081
Hormone signaling
eruf04114
Oocyte meiosis
eruf04140
Autophagy - animal
eruf04144
Endocytosis
eruf04150
mTOR signaling pathway
eruf04151
PI3K-Akt signaling pathway
eruf04152
AMPK signaling pathway
eruf04211
Longevity regulating pathway
eruf04213
Longevity regulating pathway - multiple species
eruf04510
Focal adhesion
eruf04520
Adherens junction
eruf04550
Signaling pathways regulating pluripotency of stem cells
eruf04730
Long-term depression
eruf04913
Ovarian steroidogenesis
eruf04914
Progesterone-mediated oocyte maturation
eruf05200
Pathways in cancer
eruf05202
Transcriptional misregulation in cancer
eruf05205
Proteoglycans in cancer
eruf05214
Glioma
eruf05215
Prostate cancer
eruf05218
Melanoma
eruf05224
Breast cancer
eruf05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
eruf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
138381495 (IGF1R)
04014 Ras signaling pathway
138381495 (IGF1R)
04015 Rap1 signaling pathway
138381495 (IGF1R)
04066 HIF-1 signaling pathway
138381495 (IGF1R)
04068 FoxO signaling pathway
138381495 (IGF1R)
04151 PI3K-Akt signaling pathway
138381495 (IGF1R)
04152 AMPK signaling pathway
138381495 (IGF1R)
04150 mTOR signaling pathway
138381495 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
138381495 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
138381495 (IGF1R)
04140 Autophagy - animal
138381495 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
138381495 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
138381495 (IGF1R)
04520 Adherens junction
138381495 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
138381495 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
138381495 (IGF1R)
04914 Progesterone-mediated oocyte maturation
138381495 (IGF1R)
09156 Nervous system
04730 Long-term depression
138381495 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
138381495 (IGF1R)
04213 Longevity regulating pathway - multiple species
138381495 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
138381495 (IGF1R)
05202 Transcriptional misregulation in cancer
138381495 (IGF1R)
05205 Proteoglycans in cancer
138381495 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
138381495 (IGF1R)
05214 Glioma
138381495 (IGF1R)
05218 Melanoma
138381495 (IGF1R)
05215 Prostate cancer
138381495 (IGF1R)
05224 Breast cancer
138381495 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
138381495 (IGF1R)
01522 Endocrine resistance
138381495 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
eruf01001
]
138381495 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
eruf04090
]
138381495 (IGF1R)
Enzymes [BR:
eruf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
138381495 (IGF1R)
Protein kinases [BR:
eruf01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
138381495 (IGF1R)
CD molecules [BR:
eruf04090
]
Proteins
138381495 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-GeneID:
138381495
NCBI-ProteinID:
XP_069321875
LinkDB
All DBs
Position
3:complement(15650632..15933511)
Genome browser
AA seq
1367 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNHCQKMCPSTCGKRACTENNECCHPECLGSCS
APDNATACVACRHYYYAGVCVPACPPGTYRFEGWRCVDRDFCANIPSAESSDSEGFVIHD
GECMQECPSGFIRNGTQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWRRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNLVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGDKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAMDTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
EPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEIENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIIRSVKDEMEPGFQEVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDRH
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttttctcc
gccgcgctctcgctctggccaacgagtggagaaatctgtgggccgggcatcgacatccgc
aacgactatcaacagctgaagcgcctggagaactgcacggtgatcgagggctacctccac
atcctcctcatctccaaggcggaggattaccgcagctaccgcttccccaagctcacggtc
atcaccgaatacttgctgctgttccgagtggccggcctcgagagcctcggagacctcttc
ccgaacctcacggtcatccgtggctggaaactcttctacaactacgccctggtcatcttt
gagatgacgaatctcaaagatattgggctttacaacctgaggaacatcactcggggggcc
atcaggattgagaaaaatgcggacctctgttacctgtccactgtggactggtccctgatc
ctggatgcggtgtccaataactacattgtggggaacaagcccccgaaggagtgcggggac
ctgtgtccggggaccatggaggagaagccgttgtgcgagaagaccaccatcaacaacgag
tacaactaccgctgctggaccacaaatcactgccagaaaatgtgcccgagcacgtgcggg
aagcgggcgtgcaccgagaacaacgagtgctgccaccccgagtgcctgggcagctgcagc
gcgcccgacaacgccacggcctgcgtggcctgccgccactactactacgccggcgtctgc
gtgcccgcctgcccgcccggcacctacaggttcgagggctggcgctgtgtggaccgcgac
ttctgcgccaacatccccagcgccgagagcagcgactccgaggggttcgtgatccatgac
ggcgagtgcatgcaggagtgcccctcgggcttcatccgcaatggcacgcagagcatgtac
tgcatcccttgtgaaggtccttgccccaaggtctgtgaggaagaaaagaaaacaaaaacc
attgattctgttacttctgctcagatgctccaaggatgcaccatcttcaagggcaatttg
ctcattaatatccgacgaggcaataacattgcttcggaactggagaacttcatgggactc
atcgaggtggtgacgggctacgtgaagatccgccattcccatgccttggtctccttgtcc
ttcctgaaaaacctccgcctgatcttaggagaggagcagctagaagggaattattccttc
tatgtcctcgacaaccagaacttgcaacagctgtgggactgggaccaccgcaacctgacc
atcaaagcagggaaaatgtactttgctttcaatcccaaattgtgtgtttccgaaatttac
cgtatggaggaagtgacggggactaaagggcgccaaagcaaaggggacataaacaccagg
aacaacggggagagagcctcctgtgaaagtgacgtcctgcatttcacctccaccaccacg
tggaagaatcgcattatcataacctggcgccggtaccggccccctgactacagagatctc
atcagcttcaccgtttactacaaggaagcaccctttaaaaacgtcacggagtatgatggg
caggatgcctgtggctccaacagctggaacttggtggatgtggacctcccacccaacaag
gacgttgagcccggcatcttactgcatgggctgaagccctggacccagtatgctgtgtac
gtcaaggccgtgaccctcaccatggtggagaatgaccatatccgtggggccaagagtgag
atcttgtacattcgcaccaacgcttcagttccttccattcccctggacgtactttcagca
tcaaactcctcatctcagctaatcgtgaagtggaaccctccctctctgcccaacgggaac
ctgagttactacatcgtgcggtggcagcggcagcctcaggacagctacctttaccggcac
aattactgctccaaagacaaaattcccatcaggaagtacgccgatggcaccattgacatt
gaagaggtgacagagaatcccaagaccgaagtatgtggtggagataaagggccttgctgt
gcttgtcccaagaccgaagccgagaagcaggccgagaaggaagaggctgagtaccgcaaa
gtctttgagaatttcctgcacaactccatcttcgtgcccagacctgaaaggaagcggaga
gacgtcatgcaagtggccaacaccaccatgtccagccgaagcaggaacaccacagcaatg
gacacctacaatatcacagacccagaagaacttgagacagagtaccctttctttgagagc
agagtagataacaaggagagaactgtcatttccaacctccggccttttacattgtaccgc
atcgatatccacagctgtaaccatgaggctgagaagctgggctgcagtgcctccaacttt
gtctttgcaagaactatgcctgcagaaggagcagatgacattcctgggccagtgacctgg
gagccaaggcctgaaaactccatctttttaaagtggccagaacctgagaatcccaatgga
ttgattctaatgtatgaaataaaatatggatcacaagttgaggatcaacgggaatgtgtg
tccagacaggagtacaggaagtatggaggggccaagctgaaccggctaaacccagggaac
tatacagcccggattcaggccacctctctctctgggaatggatcgtggacagaccctgtg
ttcttctatgtccaggccaaaacaggatatgaaaacttcatccacctgatcattgccctg
cccgtggccgtcctgctgatcgtgggaggcttggtgatcatgttgtacgtcttccacaga
aagagaaataacagcaggctggggaatggagtgctgtatgcttccgtgaacccagagtac
ttcagcgcggctgacgtgtacgttcctgacgagtgggaggtagcgcgagagaagatcacc
atgaaccgagagcttgggcaggggtcgtttgggatggtctacgagggagttgccaagggc
gtggttaaagatgaacctgaaaccagggtggccataaaaacggtgaatgaggccgcgagc
atgcgtgaaaggattgagtttctcaacgaggcttccgtgatgaaggagttcaattgccac
cacgtggtgcggttgctcggtgtggtgtcccagggccagccaacgctggtcatcatggag
ctgatgacacggggtgacctcaaaagttacctcaggtctctgaggccagaaatagagaat
aatccagtcctagcacctccaagtctaagcaagatgatccagatggctggagagattgca
gatggcatggcgtacctcaacgccaacaagtttgtccacagagaccttgctgcccggaac
tgcatggtggctgaagatttcacagtcaaaatcggagattttggtatgactcgagatatc
tacgagacagactattaccggaaaggagggaaaggcttgctgcccgtgcgctggatgtct
cccgagtccctcaaggatggcgtcttcaccactcactcggacgtctggtcctttggggtg
gtcctctgggagatcgccacgctggccgagcagccctaccagggcttgtccaacgagcaa
gtccttcgcttcgtcatggagggcggccttctggacaagccggacaactgccccgacatg
ctgttcgagctgatgcgcatgtgctggcagtacaaccccaagatgaggccgtccttcctg
gagatcatccgcagcgtcaaggacgagatggagcccggctttcaggaggtctccttctac
tacagcgaggagaacaagccgccggagcccgaggagctggacctggagccagagaacatg
gagagtgtccccctggacccctcggcctcctcgtcctccctgccactgcccgacagacac
tcaggacacaaggccgagaacggcccgggccctggagtgctggtcctgcgcgccagcttc
gatgagagacagccttacgcacacatgaacgggggccgcaagaacgagagggcgctgccg
ctgccccagtcctccacctgctga
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