KEGG   Eulemur rufifrons (Bennett's brown lemur): 138383938
Entry
138383938         CDS       T11398                                 
Symbol
GRM5
Name
(RefSeq) metabotropic glutamate receptor 5 isoform X1
  KO
K04604  metabotropic glutamate receptor 5
Organism
eruf  Eulemur rufifrons (Bennett's brown lemur)
Pathway
eruf04020  Calcium signaling pathway
eruf04072  Phospholipase D signaling pathway
eruf04080  Neuroactive ligand-receptor interaction
eruf04082  Neuroactive ligand signaling
eruf04540  Gap junction
eruf04720  Long-term potentiation
eruf04723  Retrograde endocannabinoid signaling
eruf04724  Glutamatergic synapse
eruf05010  Alzheimer disease
eruf05016  Huntington disease
eruf05022  Pathways of neurodegeneration - multiple diseases
eruf05215  Prostate cancer
Brite
KEGG Orthology (KO) [BR:eruf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    138383938 (GRM5)
   04072 Phospholipase D signaling pathway
    138383938 (GRM5)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    138383938 (GRM5)
   04082 Neuroactive ligand signaling
    138383938 (GRM5)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    138383938 (GRM5)
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    138383938 (GRM5)
   04720 Long-term potentiation
    138383938 (GRM5)
   04723 Retrograde endocannabinoid signaling
    138383938 (GRM5)
 09160 Human Diseases
  09162 Cancer: specific types
   05215 Prostate cancer
    138383938 (GRM5)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    138383938 (GRM5)
   05016 Huntington disease
    138383938 (GRM5)
   05022 Pathways of neurodegeneration - multiple diseases
    138383938 (GRM5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:eruf04030]
    138383938 (GRM5)
G protein-coupled receptors [BR:eruf04030]
 Metabotropic glutamate receptor family
  Glutamate (metabotropic)
   138383938 (GRM5)
SSDB
Motif
Pfam: ANF_receptor 7tm_3 GluR_Homer-bdg NCD3G Peripla_BP_6 DUF5438
Other DBs
NCBI-GeneID: 138383938
NCBI-ProteinID: XP_069325185
LinkDB
Position
6:40884952..41365833
AA seq 1212 aa
MVLLLILSVLLLKEDVRGSAQSNERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAV
REQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISS
EEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLS
DKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMAAKEGI
CIAHSYKIYSNAGEQSFDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFL
LLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNLRNPWFQEFWQ
HRFQCRLEGFPQENSKYNKTCNSSLTLRTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCP
GYAGLCDAMKPIDGRKLLDSLMKTNFTGVSGDMILFDENGDSPGRYEIMNFKEMGKDYFD
YINVGSWDNGELKMDDDEVWSKKSTIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKEN
EYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTAV
FIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYS
ALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIM
HDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYT
TCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTS
TVVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETLRYKDRRLAQHKSEIECFTPKGSMG
NGGRATMSSSNGKSVTWAQNEKSSRGQHLWQRLSVHINKKENPNQTAVIKPFPKSTESRG
LGAGAGAASGAGSAGGATGASCTGAGPGGPEPPDASPKALYDVAEAEEHFPAPARPRSPS
PISTLSQRAGSASRTEDDVPSLHSEPAARSSSSQGSLMEQISSVVTRFTANISELNSMML
STAAPGPGVGAPLCSSYLIPKEIQLPTTMTTFAEIQPLPAIEVTGGAQPVAGVPPAGGAA
GEAPAAGPEAAAGKQDLEELVALTPPSPFRDSVDSGSTTPNSPVSESALCIPSSPKYDTL
IIRDYTQSSSSL
NT seq 3639 nt   +upstreamnt  +downstreamnt
atggtccttctgttgatcctgtcagtcctgcttttgaaagaagatgtccgtgggagtgca
cagtccaatgagaggagggtggtggctcacatgccaggtgacatcattatcggagctctc
ttttctgtccaccaccagcctaccgtggacaaagttcacgagaggaagtgtggggcagtc
cgtgaacagtatggcattcagagagtggaggccatgctgcacaccctggaaagaatcaat
tcagaccccacactcttgcccaacatcacactgggctgtgagataagggattcctgctgg
cattcggctgtggccctagagcagagcattgagttcataagggattccctcatttcttca
gaagaggaagagggcttggtacgctgtgtggatggctcttcttcttccttccgttccaag
aagcccatagtaggggtcattgggcctggctccagttctgtggccattcaggtccagaac
ttgctccagcttttcaacatacctcagattgcttactcggcaaccagcatggatctgagt
gacaagactctgttcaagtacttcatgagggttgtgccttcagatgcccagcaggcacgg
gccatggtggacatagtgaagagatacaactggacttacgtgtcagcggtgcacacagaa
ggcaactatggagaaagtgggatggaagctttcaaagatatggcagcaaaggaggggatt
tgcatcgcgcactcttataaaatctacagcaacgcaggggagcagagcttcgataagctg
ttgaagaagctcacgagtcatctgcccaaggctcgggtggtggcctgcttctgtgagggc
atgacggtgagaggcctgctgatggccatgaggcgcctgggtctagcaggagaatttctg
cttctgggcagcgatggctgggccgacaggtatgacgtgacggatggatatcagcgagaa
gctgttggtggaattacaatcaagctccaatctcccgatgtcaagtggtttgatgattat
tatctgaagctccggccagaaacaaacctccgaaacccttggtttcaagaattttggcag
catcgttttcaatgccggctggaagggtttccacaggagaacagcaaatacaacaagact
tgcaatagttctctaactctgagaacacatcatgttcaagattccaaaatgggatttgtg
atcaacgcaatctattccatggcctatgggctccacaacatgcagatgtccctctgccca
ggctacgcaggactttgtgatgcaatgaagccaattgatggacggaaacttttggactcc
ctgatgaaaaccaattttactggagtttctggagatatgatcctattcgatgagaatgga
gactctccaggaaggtatgaaataatgaatttcaaggaaatgggaaaagattattttgat
tacatcaacgttgggagttgggacaatggagaattaaaaatggatgatgatgaggtatgg
tccaagaaaagcaccatcatcagatctgtgtgcagtgaaccatgtgagaaaggccagata
aaggtgatccggaagggagaagtcagctgttgttggacctgtacgccttgtaaagaaaat
gagtatgtctttgatgaatacacctgcaaagcgtgccagctggggtcctggcccaccgat
gatcttacaggctgtgatttgatcccagtacagtatctccgatggggtgacccggagccc
atcgcagccgtggtgtttgcctgcctgggtctgctggccaccctgtttgttaccgcagtc
ttcatcatttaccgcgatacaccagtagtcaagtcctccagcagggaactctgctacatt
atccttgccggcatctgcctgggctacttatgtaccttctgcctcatcgcaaagcccaaa
cagatttattgctaccttcagagaattggcatcggtctctctccagccatgagctattca
gcccttgtaaccaagaccaaccgtattgcaaggatcctggctggcagcaagaagaagatc
tgtaccaaaaagcccagattcatgagtgcctgtgcccagctcgtgattgctttcattctc
atatgcatccagctgggcatcatagtcgccctctttataatggagcctcctgacataatg
catgactacccaagcattcgggaagtctacctgatctgcaacaccaccaacctaggagtt
gtcactcctcttggatacaatggattgttgattttaagctgcaccttctatgctttcaag
accagaaatgttccagctaacttcaacgaggccaagtatatcgccttcacaatgtatacc
acctgcattatatggctggcctttgtgccaatctactttggcagcaactacaaaatcatc
accatgtgtttctcggtcagcctcagtgccacagtggccctaggctgcatgtttgtgccg
aaggtgtacatcatcctggccaaaccagagagaaatgtgcgcagcgccttcaccacgtct
actgtggtgcgcatgcacgtgggggacggcaagtcgtcctccgcagccagcagatccagc
agcctagtcaacctgtggaagaggaggggctcctctggggaaaccctaaggtacaaagac
aggagactggcccagcacaagtcggaaatagagtgtttcacccccaaagggagtatgggg
aatggtgggagagcaacaatgagcagctccaatggaaaatccgtcacgtgggcccagaac
gagaagagcagccgggggcagcacctgtggcagcggctctccgtccacatcaacaagaaa
gagaaccccaaccaaacggccgtcatcaagcccttccccaagagcaccgagagccgaggc
ctgggcgccggcgcgggggccgcgagcggcgcggggagtgcgggcggcgcaaccggggcg
agctgcacgggcgccggccccggcgggcccgagccccccgacgccagccccaaggcgttg
tacgacgtggccgaggccgaggagcacttcccggcgcccgcgcggccgcgctcgccgtcg
cccatcagcacgctgagccagcgcgcgggctcggccagccgcacggaagacgacgtgccg
tcgttgcactcggagcccgcggcgcgcagcagctcctcgcagggctcgctcatggagcag
atcagcagcgtggtgacccgcttcacggccaacatcagcgagctcaactccatgatgctg
tccaccgcggctcccggcccgggcgtgggtgccccgctctgctcttcctacctgatcccc
aaagagattcagctgcctacgaccatgacgacgttcgccgaaatccagcccctgccggcc
atcgaggtcacgggcggcgcgcagccggtggcgggggtcccgccggctgggggcgctgca
ggggaggcccccgcggccgggcctgaggctgcggctggcaagcaagacctggaggagttg
gtggctctcaccccgccgtcccccttcagagactcggtggactcggggagtacaaccccc
aactcgccagtgtccgagtcggccctctgtatcccatcgtctcccaaatacgacactctt
atcataagagattacactcagagctcctcgtcgttgtga

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