KEGG   Eulemur rufifrons (Bennett's brown lemur): 138387912
Entry
138387912         CDS       T11398                                 
Symbol
GSK3B
Name
(RefSeq) glycogen synthase kinase-3 beta isoform X1
  KO
K03083  glycogen synthase kinase 3 beta [EC:2.7.11.26]
Organism
eruf  Eulemur rufifrons (Bennett's brown lemur)
Pathway
eruf01521  EGFR tyrosine kinase inhibitor resistance
eruf04012  ErbB signaling pathway
eruf04062  Chemokine signaling pathway
eruf04110  Cell cycle
eruf04150  mTOR signaling pathway
eruf04151  PI3K-Akt signaling pathway
eruf04310  Wnt signaling pathway
eruf04340  Hedgehog signaling pathway
eruf04360  Axon guidance
eruf04390  Hippo signaling pathway
eruf04510  Focal adhesion
eruf04517  IgSF CAM signaling
eruf04518  Integrin signaling
eruf04550  Signaling pathways regulating pluripotency of stem cells
eruf04657  IL-17 signaling pathway
eruf04660  T cell receptor signaling pathway
eruf04662  B cell receptor signaling pathway
eruf04722  Neurotrophin signaling pathway
eruf04728  Dopaminergic synapse
eruf04910  Insulin signaling pathway
eruf04916  Melanogenesis
eruf04917  Prolactin signaling pathway
eruf04919  Thyroid hormone signaling pathway
eruf04931  Insulin resistance
eruf04932  Non-alcoholic fatty liver disease
eruf04934  Cushing syndrome
eruf04935  Growth hormone synthesis, secretion and action
eruf04936  Alcoholic liver disease
eruf05010  Alzheimer disease
eruf05020  Prion disease
eruf05022  Pathways of neurodegeneration - multiple diseases
eruf05135  Yersinia infection
eruf05160  Hepatitis C
eruf05162  Measles
eruf05163  Human cytomegalovirus infection
eruf05165  Human papillomavirus infection
eruf05167  Kaposi sarcoma-associated herpesvirus infection
eruf05200  Pathways in cancer
eruf05210  Colorectal cancer
eruf05213  Endometrial cancer
eruf05215  Prostate cancer
eruf05217  Basal cell carcinoma
eruf05224  Breast cancer
eruf05225  Hepatocellular carcinoma
eruf05226  Gastric cancer
eruf05415  Diabetic cardiomyopathy
eruf05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:eruf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    138387912 (GSK3B)
   04310 Wnt signaling pathway
    138387912 (GSK3B)
   04340 Hedgehog signaling pathway
    138387912 (GSK3B)
   04390 Hippo signaling pathway
    138387912 (GSK3B)
   04151 PI3K-Akt signaling pathway
    138387912 (GSK3B)
   04150 mTOR signaling pathway
    138387912 (GSK3B)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    138387912 (GSK3B)
   04518 Integrin signaling
    138387912 (GSK3B)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    138387912 (GSK3B)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    138387912 (GSK3B)
   04550 Signaling pathways regulating pluripotency of stem cells
    138387912 (GSK3B)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    138387912 (GSK3B)
   04657 IL-17 signaling pathway
    138387912 (GSK3B)
   04662 B cell receptor signaling pathway
    138387912 (GSK3B)
   04062 Chemokine signaling pathway
    138387912 (GSK3B)
  09152 Endocrine system
   04910 Insulin signaling pathway
    138387912 (GSK3B)
   04917 Prolactin signaling pathway
    138387912 (GSK3B)
   04935 Growth hormone synthesis, secretion and action
    138387912 (GSK3B)
   04919 Thyroid hormone signaling pathway
    138387912 (GSK3B)
   04916 Melanogenesis
    138387912 (GSK3B)
  09156 Nervous system
   04728 Dopaminergic synapse
    138387912 (GSK3B)
   04722 Neurotrophin signaling pathway
    138387912 (GSK3B)
  09158 Development and regeneration
   04360 Axon guidance
    138387912 (GSK3B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    138387912 (GSK3B)
  09162 Cancer: specific types
   05210 Colorectal cancer
    138387912 (GSK3B)
   05225 Hepatocellular carcinoma
    138387912 (GSK3B)
   05226 Gastric cancer
    138387912 (GSK3B)
   05217 Basal cell carcinoma
    138387912 (GSK3B)
   05215 Prostate cancer
    138387912 (GSK3B)
   05213 Endometrial cancer
    138387912 (GSK3B)
   05224 Breast cancer
    138387912 (GSK3B)
  09172 Infectious disease: viral
   05160 Hepatitis C
    138387912 (GSK3B)
   05162 Measles
    138387912 (GSK3B)
   05163 Human cytomegalovirus infection
    138387912 (GSK3B)
   05167 Kaposi sarcoma-associated herpesvirus infection
    138387912 (GSK3B)
   05165 Human papillomavirus infection
    138387912 (GSK3B)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    138387912 (GSK3B)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    138387912 (GSK3B)
   05020 Prion disease
    138387912 (GSK3B)
   05022 Pathways of neurodegeneration - multiple diseases
    138387912 (GSK3B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    138387912 (GSK3B)
   05415 Diabetic cardiomyopathy
    138387912 (GSK3B)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    138387912 (GSK3B)
   04932 Non-alcoholic fatty liver disease
    138387912 (GSK3B)
   04931 Insulin resistance
    138387912 (GSK3B)
   04934 Cushing syndrome
    138387912 (GSK3B)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    138387912 (GSK3B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:eruf01001]
    138387912 (GSK3B)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:eruf03036]
    138387912 (GSK3B)
Enzymes [BR:eruf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.26  tau-protein kinase
     138387912 (GSK3B)
Protein kinases [BR:eruf01001]
 Serine/threonine kinases: CMGC group
  GSK family [OT]
   138387912 (GSK3B)
Chromosome and associated proteins [BR:eruf03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    138387912 (GSK3B)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kinase-like Kdo APH
Other DBs
NCBI-GeneID: 138387912
NCBI-ProteinID: XP_069331201
LinkDB
Position
7:complement(62808814..63007502)
AA seq 433 aa
MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPN
VKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAGSTPTNATAASDANAGDRGQ
TNNAASASASNST
NT seq 1302 nt   +upstreamnt  +downstreamnt
atgtcagggcggcccagaaccacctcctttgcggagagctgcaagccagtgcagcagcct
tcggcttttggcagcatgaaagttagcagagacaaggatggcagcaaggtgaccacagtg
gtagcaactcctgggcagggtccagacaggccacaagaagtcagctatacggacactaaa
gtgattggaaatgggtcatttggtgtagtatatcaagccaaactttgtgattcaggagaa
ctggttgccattaagaaggtattacaggacaaaagatttaagaaccgagagctccagatc
atgagaaagctagatcactgtaacatagtccgattgcgttatttcttctactccagcggt
gagaagaaagatgaggtctatcttaatctggtgctggactatgttccagaaacagtgtac
agagttgccagacactatagtcgagccaaacagacgctccctgtgatctatgtcaagttg
tatatgtatcagctgttccgaagtttagcctatatccattcctttggaatctgccatcgg
gatattaaaccacagaacctcttgctggatcctgatacagctgtcttaaaactctgtgac
tttggaagtgcaaagcagctggtccgaggagaacccaatgtttcctatatctgttctcgg
tactatagggcaccagagttgatctttggagccactgattatacctctagtatagatgta
tggtctgctggctgtgtgttggctgagctgttgctaggacaaccaatatttccaggggac
agtggggtggatcaattggtggaaataatcaaggtcctgggaacaccaacaagggagcaa
attagagaaatgaacccaaattacacagaattcaaattccctcaaattaaggcacatcct
tggactaaggattcgtcaggaacaggacatttcacctcaggagtgcgggtcttccgaccc
cgaactccaccagaggcaattgcactgtgtagccgtctgctggagtatacaccaactgcc
cgattgacaccactggaagcttgtgcacattcattttttgatgaattacgggacccaaat
gtcaaactaccaaatgggcgagacacacctgcactcttcaactttaccactcaagaactg
tcaagtaatccacctctggctactatccttattcctcctcatgctcggattcaagcagct
ggttcaacccccacaaatgccacagcagcctcagatgctaatgctggagaccgtggacag
accaataacgccgcttctgcatcagcttccaactccacctga

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