Eulemur rufifrons (Bennett's brown lemur): 138388069
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Entry
138388069 CDS
T11398
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
eruf Eulemur rufifrons (Bennett's brown lemur)
Pathway
eruf01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
eruf00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
138388069 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
eruf03032
]
138388069 (TOP2B)
03036 Chromosome and associated proteins [BR:
eruf03036
]
138388069 (TOP2B)
Enzymes [BR:
eruf01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
138388069 (TOP2B)
DNA replication proteins [BR:
eruf03032
]
Eukaryotic type
DNA Topoisomerases
138388069 (TOP2B)
Chromosome and associated proteins [BR:
eruf03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
138388069 (TOP2B)
Centrosome formation proteins
Centriole proteins
138388069 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-GeneID:
138388069
NCBI-ProteinID:
XP_069331556
LinkDB
All DBs
Position
7:complement(133933042..133997429)
Genome browser
AA seq
1623 aa
AA seq
DB search
MAKSGGGGVGAIAGGNGALTWVTLFDQNNAAKNEESETANKNDSSKKLSVERVYQKKTQL
EHILLRPDTYIGSVEPLTQVMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDK
NMTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTG
GRNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQ
PDLPKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLD
ETGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEV
VKKKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFK
AASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILT
EGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKK
SYDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKA
SKNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRY
AGPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFIN
KELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHG
EQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPA
VDDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRML
DGLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVL
EPMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSM
VLFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQ
GKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGP
DFNYILNMSLWSLTKEKVEELIKQRDSKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEA
QEREDVLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKRK
KGDLDTTAVKVEFDEEFSGTPVEGTGEEVLTPSGPLNKGPKPKRERKEPGTRVRKTPTSS
GKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDD
ADDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSSHDKKSQ
DFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSD
TASKPKRAPKQKKIVETVNSDSDSEFGIPKKTTAPKGKGRGAKKRKASGSENEADYNPAR
KIPKTTSKKPKKTSFDQDSDVDIFPSDFTSEPPSLPRTGRARKEVKYFTESDEEEDVDFA
MFN
NT seq
4872 nt
NT seq
+upstream
nt +downstream
nt
atggccaagtcgggtggcggcggcgtgggagccatcgcgggcggcaacggggcgctgacc
tgggtgactctttttgatcagaacaatgctgcaaaaaatgaagagtcagagactgcaaac
aaaaatgattcttcaaagaagttgtctgttgagagagtgtatcagaagaagacacaactt
gaacacattcttcttcgtcctgatacatacattgggtcagtggagccattgacccaggta
atgtgggtgtatgatgaagatgtagggatgaattgcagagaggttacctttgtgccaggt
ttatacaagatctttgatgaaattttggttaatgctgcagacaataaacagagggataag
aacatgacctgtattaaagtttctattgatcctgaatctaacattataagcatttggaat
aatgggaaaggcattccagtagtagaacacaaagtagagaaagtttatgttcctgcttta
atttttggacagcttttaacatctagtaactatgatgatgatgagaaaaaagttacaggt
ggtcgcaatggttatggtgcaaaactttgtaatattttcagtacaaagttcacagtagaa
acagcttgcaaagagtacaaacacagttttaagcagacatggatgaataatatgatgaag
acttctgaagccaaaattaaacattttgatggtgaagattacacatgcataacattccaa
ccagatctgcccaaatttaagatggaaaaacttgacaaggatattgtggccctcatgacc
agaagagcatatgatttggctggttcatgtaaaggggtcaaggtcatgtttaatggaaag
aaattgcctgtaaatggatttcgaagttatgtagatctttatgtgaaagacaaattggat
gaaactggggtggcactgaaagttattcatgaacttgcaaatgaaagatgggatgtttgt
ctcacattgagtgagaaaggattccagcaaatcagctttgtaaatagtattgcaactaca
aaaggtggacgacatgtcgattatgtagttgatcaagttgtgggtaaattgattgaagta
gttaagaaaaagaacaaagctggtgtatcagtgaaaccatttcaagtaaaaaaccacata
tgggtttttattaattgccttattgaaaatccaacatttgattctcagaccaaggaaaac
atgactctgcagcccaaaagttttgggtccaaatgtcaactgtcagaaaaattttttaaa
gcagcctctaattgtggcattgtagaaagtatcctgaactgggtgaaatttaaggctcag
actcagctgaacaagaagtgttcctcagtaaaatacagtaaaatcaaaggtattcccaaa
ctggatgatgctaatgatgctggtggcaaacattccttggagtgtacactgatactaaca
gagggagactctgccaaatcactggctgtgtctggattaggtgtgattgggcgggacaga
tacggagtttttccactcaggggtaaaattcttaatgtacgggaagcttctcacaaacag
atcatggaaaatgcagaaataaacaatattattaaaatagttggtctacaatataagaag
agttatgatgatgcagaatctttgaaaaccttacgttatggaaagattatgattatgact
gatcaggatcaagatggttctcacataaaaggcctgcttattaatttcatccatcacaat
tggccatcacttttgaagcatggttttcttgaagagttcattactcctattgtaaaggcg
agcaaaaataagcaggaactttccttctacagtattcctgaatttgatgagtggaaaaaa
catatagaaaaccagaaagcctggaaaataaaatactacaaaggtttgggtaccagtaca
gctaaagaagcaaaagaatattttgctgatatggaacggcatcgcatcttgtttagatat
gctggtcctgaagatgatgctgccattaccttggcattcagtaagaagaagattgatgac
agaaaagaatggttaacaaatttcatggaagatcggagacagcgtaggttacatggcttg
ccagagcaatttttatatggtacagcaacaaagcatttgacttacaatgattttatcaac
aaggaattgattctcttctcaaactcagacaatgaaagatctataccatctcttgttgat
ggctttaaacctgggcaacgaaaagttttatttacctgtttcaagaggaatgataaacgt
gaggtaaaagttgcccagttggctggatctgttgctgaaatgtctgcttatcatcatgga
gaacaagcattgatgatgactattgtgaatttggctcagaactttgtgggaagtaacaac
attaacttgcttcagcctattggtcagtttggaactcggcttcatggtggcaaagatgct
gcaagccctcgttatattttcacaatgttaagctctttagcaagactgctttttcctgct
gtggatgataacttgcttaagttcctttatgatgataatcagcgtgtagagcctgagtgg
tatattcccataattcccatggttttaataaatggtgctgagggcattggtactggatgg
gcttgtaagctacccaactatgatgctagggaaattgtgaacaatgtcagacgaatgcta
gatggcttggatcctcatcccatgcttccaaactacaaaaactttaaaggcacgatccaa
gaacttggtcaaaaccagtatgcagtcagtggtgaaatatttgtagtggatagaaacaca
gtagaaattacagagcttccagttagaacttggacacaggtatacaaagaacaggtttta
gaacctatgctaaatggaacagacaaaacaccagcattaatttctgattataaagaatat
catactgatacaactgtgaaatttgtggtgaaaatgactgaagagaaactagcacaagca
gaagctgctggattgcataaagtttttaaacttcaaactactcttacttgtaattccatg
gtactctttgatcatatgggatgtctgaagaagtatgaaactgtgcaagacattctgaaa
gaattctttgatttacgattaagttattacggtttacgtaaggagtggcttgtaggaatg
ttgggagcagaatctacaaagcttaataatcaagcccgtttcattttagagaagatacaa
gggaaaattactatagagaataggtcaaagaaagatttgattcaaatgttagtccagaga
ggttatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagag
gaagaaacacaaaaccagcatgatgatagttcctccgattcaggaactccttcaggccct
gattttaattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaa
ctgattaaacaaagagattcaaaagggcgagaggtcaatgatcttaaaagaaaatctcct
tcagatctttggaaagaagatttagcagcatttgttgaagaactggataaagttgaagcg
caagaacgagaagatgttctggctggaatgtcaggaaaagcaataaaaggtaaagttggc
aagcctaaggtgaagaaacttcaattggaagagacaatgccctcaccttatgggagaaga
ataattcctgaaattactgctatgaaggcggatgccagcaaaaagttgctgaagaggaag
aagggtgaccttgataccacagcagtaaaagtggaatttgatgaagaattcagtggaaca
ccagtagaaggtacaggagaggaggtgttgactccatcgggtcctctaaataaaggtccc
aaacccaaaagggagagaaaggagcctggtaccagggtgagaaaaacacctacatcatct
ggtaaacccagtgcaaagaaagtgaagaaacggaatccttggtcagatgatgaatccaag
tcagaaagtgatttggaagaaacagaacctgtggttattccaagagattctttgcttagg
agagcagctgctgaaagacctaagtacacatttgatttctcagaagaagaggatgatgat
gctgatgatgatgatgacaataatgatttagaggaattgaaagttaaagcatctcccata
acaaatgatggggaagatgaatttgttccttcagatggcttagataaagatgaatatacg
ttttcaccaggcaaatcaaaagctactccagaaaaatcttcacatgacaaaaaaagtcag
gattttggaaatctcttctcatttccttcatattctcagaagtcagaagatgattcagct
aaattcgacagtaatgaagaagattctgcttcggttttttcaccatcatttggtctgaaa
caaacagataaagttccaagtaaaacagtagctgctaaaaagggaaaaccatcttcagat
acagcctctaagcctaagagagcccccaaacagaagaaaatagtagagactgtaaactct
gactcagattcagaatttggcattccaaagaagactacagcgccaaaaggtaaaggccga
ggggcaaagaaaaggaaagcatctggctctgaaaatgaagccgattataaccctgccagg
aaaatacccaaaacaacaagcaagaaaccgaagaaaacatcatttgatcaggattcagat
gtggacatcttcccctcagactttacttctgaaccaccttctctgccacggactggtcga
gctaggaaagaagtaaaatattttacagagtctgatgaagaagaagatgttgattttgca
atgtttaattaa
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