Eulemur rufifrons (Bennett's brown lemur): 138388235
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Entry
138388235 CDS
T11398
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
KO
K04851
voltage-dependent calcium channel L type alpha-1D
Organism
eruf Eulemur rufifrons (Bennett's brown lemur)
Pathway
eruf04010
MAPK signaling pathway
eruf04020
Calcium signaling pathway
eruf04022
cGMP-PKG signaling pathway
eruf04024
cAMP signaling pathway
eruf04218
Cellular senescence
eruf04260
Cardiac muscle contraction
eruf04261
Adrenergic signaling in cardiomyocytes
eruf04270
Vascular smooth muscle contraction
eruf04530
Tight junction
eruf04713
Circadian entrainment
eruf04723
Retrograde endocannabinoid signaling
eruf04724
Glutamatergic synapse
eruf04725
Cholinergic synapse
eruf04726
Serotonergic synapse
eruf04727
GABAergic synapse
eruf04728
Dopaminergic synapse
eruf04911
Insulin secretion
eruf04912
GnRH signaling pathway
eruf04921
Oxytocin signaling pathway
eruf04924
Renin secretion
eruf04925
Aldosterone synthesis and secretion
eruf04927
Cortisol synthesis and secretion
eruf04929
GnRH secretion
eruf04930
Type II diabetes mellitus
eruf04934
Cushing syndrome
eruf04935
Growth hormone synthesis, secretion and action
eruf04973
Carbohydrate digestion and absorption
eruf05010
Alzheimer disease
eruf05020
Prion disease
eruf05022
Pathways of neurodegeneration - multiple diseases
eruf05031
Amphetamine addiction
eruf05207
Chemical carcinogenesis - receptor activation
eruf05410
Hypertrophic cardiomyopathy
eruf05412
Arrhythmogenic right ventricular cardiomyopathy
eruf05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
eruf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
138388235 (CACNA1D)
04020 Calcium signaling pathway
138388235 (CACNA1D)
04024 cAMP signaling pathway
138388235 (CACNA1D)
04022 cGMP-PKG signaling pathway
138388235 (CACNA1D)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
138388235 (CACNA1D)
09144 Cellular community - eukaryotes
04530 Tight junction
138388235 (CACNA1D)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
138388235 (CACNA1D)
04929 GnRH secretion
138388235 (CACNA1D)
04912 GnRH signaling pathway
138388235 (CACNA1D)
04921 Oxytocin signaling pathway
138388235 (CACNA1D)
04935 Growth hormone synthesis, secretion and action
138388235 (CACNA1D)
04924 Renin secretion
138388235 (CACNA1D)
04925 Aldosterone synthesis and secretion
138388235 (CACNA1D)
04927 Cortisol synthesis and secretion
138388235 (CACNA1D)
09153 Circulatory system
04260 Cardiac muscle contraction
138388235 (CACNA1D)
04261 Adrenergic signaling in cardiomyocytes
138388235 (CACNA1D)
04270 Vascular smooth muscle contraction
138388235 (CACNA1D)
09154 Digestive system
04973 Carbohydrate digestion and absorption
138388235 (CACNA1D)
09156 Nervous system
04724 Glutamatergic synapse
138388235 (CACNA1D)
04727 GABAergic synapse
138388235 (CACNA1D)
04725 Cholinergic synapse
138388235 (CACNA1D)
04728 Dopaminergic synapse
138388235 (CACNA1D)
04726 Serotonergic synapse
138388235 (CACNA1D)
04723 Retrograde endocannabinoid signaling
138388235 (CACNA1D)
09159 Environmental adaptation
04713 Circadian entrainment
138388235 (CACNA1D)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
138388235 (CACNA1D)
09164 Neurodegenerative disease
05010 Alzheimer disease
138388235 (CACNA1D)
05020 Prion disease
138388235 (CACNA1D)
05022 Pathways of neurodegeneration - multiple diseases
138388235 (CACNA1D)
09165 Substance dependence
05031 Amphetamine addiction
138388235 (CACNA1D)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
138388235 (CACNA1D)
05412 Arrhythmogenic right ventricular cardiomyopathy
138388235 (CACNA1D)
05414 Dilated cardiomyopathy
138388235 (CACNA1D)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
138388235 (CACNA1D)
04934 Cushing syndrome
138388235 (CACNA1D)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
eruf04040
]
138388235 (CACNA1D)
Ion channels [BR:
eruf04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
138388235 (CACNA1D)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
CAC1F_C
Ca_chan_IQ
GPHH
PKD_channel
NCAPD3_N
Motif
Other DBs
NCBI-GeneID:
138388235
NCBI-ProteinID:
XP_069331991
LinkDB
All DBs
Position
7:157742059..158051829
Genome browser
AA seq
2180 aa
AA seq
DB search
MMMMMMMKKMQHQRQQQTDHANEANYARGTRLPLSAEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGGEEGKRNTSMPTSETESVNTENVS
GEGETQGCCGSLWCWWRRRGAAKAGPSGCQRWGQAISKSKLSRRWRRWNRFNRRRCRAAV
KSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQ
AYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLV
ASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQ
ILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES
LNTAQKEEAEEKERKKIARKESLENKKNKPEVNQIANSDNKVTIDDYREEDEDKDPYPPC
DVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHK
LINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTTF
GAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGL
KHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFIL
YKDGDVDTPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPV
YNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALK
ARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILN
MVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADPTESENVPVPT
ATPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLF
FIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLC
DPESDYSPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHH
LDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSD
GTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEV
TVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCD
LQDDEPEETKREEEEDIFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPPA
SDTEKPLFPPAGNSVCHNHHNHNSIGKHVPTSTNANLNNANMSKAAHGKRPSLGNLEHVS
ENGHHSSHKHDREPQRRSSIKRTRYYETYIRSDSGDEQLPTICREDPEIHGYFRDPRCLG
EQEYFSSEECYEDDSSPPGSRQTYGYYSRYTGSNSDFERPRGYHHPQGFLEDDDSPVCYD
SRRSPRRRLLPPTPTSHRRSSFNFECLRRQSSQEEVPLSPAFPHRTALPLHLMQQQIMAV
AGLDSSKAQKYSPSHSTRSWATPPATPPYRDWTPCYTPLIQVDRSESLDQVNGSLPSLHR
SSWYTDEPDISYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKFV
SATKHEIADACDLTIDEMESAASTLLNGSVHRRANGDVGPVSHRQDYELQDFGPGYSDDE
PDLGRDEEDLADEMICITTL
NT seq
6543 nt
NT seq
+upstream
nt +downstream
nt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcagcaaacggaccac
gcgaacgaggcaaactatgcaagaggcaccagactccctctttctgctgaaggaccaact
tctcagccgaatagctccaagcaaactgtcctgtcttggcaagctgcaatcgatgctgct
agacaggccaaggctgcccaaactatgagcacctctgcacccccacctgtaggatctctt
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccaacagc
cgacctgcccgcgcccttttctgtttgtcactcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagatt
atagcgtatggattattgctgcatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaa
acagaaggcgggaaccactctagcggcaaatcaggaggctttgatgtcaaagccctccgt
gcctttcgagtgttacgaccacttcgactagtgtcaggagtgcccagtttacaagttgtc
ctgaactccattataaaagccatggttcccctccttcacatagcccttttggtattattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgtttttttgctgactcagatatcgtagctgaagaggacccagctccgtgtgcgttctca
gggaatggacgccagtgtaccgccaatggcacggaatgtaggagcggctgggttggcccg
aatggaggcatcaccaactttgataactttgcctttgccatgctcactgtgtttcagtgc
atcaccatggagggctggacagacgtgctctactgggtaaatgatgcgataggatgggaa
tggccatgggtgtattttgttagtctgatcatccttggctcatttttcgtccttaacctg
gttcttggtgtccttagtggagaattttcaaaggaaagagagaaggctaaagcacgggga
gacttccagaagctccgggagaagcagcagctggaagaggatctaaagggctacttggat
tggattacccaagcagaagatatcgatcccgagaatgaggatgaaggaggagaggaaggc
aaacgaaatactagcatgcccaccagtgagaccgaatctgtgaacacggagaacgtgagt
ggcgaaggcgagacccagggctgctgtgggagtctctggtgctggtggagaagaagaggc
gcggccaaggctgggccctcagggtgtcagcggtggggtcaagccatctcaaaatccaaa
ctcagtcgacgctggcgtcgctggaaccggttcaatcgcagaagatgtagggctgccgtg
aagtctgtcacgttttactggctggttattgtcctggtgtttctcaacaccttaaccatt
tcctccgagcactacaaccagccagattggttgacacagattcaagatattgctaacaaa
gtcctcttggctctgttcacctgcgagatgctggtaaaaatgtacagcttgggcctccaa
gcatatttcgtctctcttttcaaccggtttgactgcttcgtggtgtgcggcggaattact
gaaaccatcttggtggaactggaaatcatgtctcccctgggcatctctgtgtttcggtgt
gtgcgtctcttaagaatcttcaaagtgaccaggcactggacttccctcagcaacttggtg
gcatccttgttaaactccatgaagtccattgcttcgctattgcttctgctttttcttttc
atcatcatcttttccttgcttgggatgcagctgtttggcggcaagtttaatttcgatgaa
acgcaaaccaagcggagcaccttcgacaatttcccgcaagcacttctcacggtgttccag
atcctgacaggtgaagactggaatgctgtgatgtacgacggcatcatggcttatgggggc
ccgtcctcttcaggaatgattgtctgcatctacttcatcatcctcttcatttgtggtaac
tatattctactgaacgtcttcttggccattgctgtagacaatttggctgatgctgaaagt
ttgaacactgctcagaaagaagaagcagaagaaaaggaaaggaaaaagattgccagaaaa
gagagcttagaaaataaaaagaacaaaccagaagtcaaccagatagccaacagtgacaac
aaggttacaattgatgactatcgagaagaggatgaagacaaggacccctacccaccttgt
gacgtgccagtaggtgaagaggaagaagaagaggaagaggatgaacctgaggttcctgct
ggtccccgtcctcgcagaatctcagagttgaacatgaaggagaaaatcgcccccatccct
gaagggagcgccttcttcattctcagcaagaccaacccgatccgcgtgggctgccacaag
ctcatcaaccaccacatcttcaccaacctcatcctcgtcttcatcatgctgagcagcgcc
gccctcgccgccgaggaccccatccgcagccactccttccggaacactatactgggttac
tttgactatgccttcacagccatctttactgttgagatcctgttgaagatgacgactttt
ggcgctttcctccacaaaggggctttctgcaggaactacttcaatttgctggacatgctg
gttgttggggtgtctctggtgtcatttgggattcaatccagtgccatctccgtggtgaag
attctgagggtcttaagggttctgaggcccctcagagcaatcaacagagcaaaaggactt
aagcacgtggtccagtgcgtctttgtggccatccggaccatcggcaacatcatgatcgtc
accaccctcctccagttcatgttcgcctgcatcggtgtccagctgttcaaggggaagttc
tatcgctgcacagatgaagccaaaagtaaccctgaagagtgcagggggcttttcatcctc
tacaaggatggggacgttgatacccctgtggtccgtgagcggatctggcagaacagtgac
ttcaactttgacaacgtgctctctgccatgatggcgctcttcaccgtctccacgtttgag
ggctggcccgcgttgctgtacaaagctatcgactcgaacggagagaacgtcggcccagtc
tacaaccaccgcgtggagatctccatcttcttcatcatctacatcatcattgtagctttc
ttcatgatgaacatctttgtgggctttgtcatcgttacatttcaggagcagggggaaaaa
gagtataagaactgtgagctggacaagaatcagcgtcagtgtgttgaatacgccttgaaa
gcacgtcccttgcggagatacatccccaaaaacccctaccagtacaagttctggtacgtg
gtgaactcttcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactctgc
ttggccatgcagcactacgagcagtccaagatgttcaacgacgccatggacattctgaac
atggtcttcactggggtgttcaccgttgagatggttttaaaagtcattgcatttaagcct
aaggggtattttagtgacgcctggaacacgtttgactccctcatcgtaatcggcagcatt
atagacgtggccctcagcgaagcagacccaactgaaagtgaaaatgtccctgtcccaact
gctacacctgggaactctgaagaaagcaatagaatctccatcacctttttccgtcttttc
cgagtgatgcgattggtgaagcttctcagcaggggggaaggcatccggacgctgctgtgg
accttcattaagtcctttcaggcgctcccgtatgtcgcccttctcatagccatgctgttc
ttcatctacgcggtcatcggcatgcagatgtttgggaaagttgccatgagagataacaac
cagatcaataggaacaacaactttcagacgtttccccaggcggtgctgctgctcttcagg
tgtgcaacaggtgaggcctggcaagagatcatgctggcctgcctcccggggaagctgtgt
gaccctgagtcggattacagccccggggaggagtatacgtgtgggagcaactttgccatc
gtctatttcatcagcttttacatgctgtgtgcgtttctgatcatcaatctgtttgtggct
gtcattatggacaattttgattatctgacccgggactggtctattctggggcctcaccat
ttagatgaattcaaaagaatatggtcagaatatgaccctgaggcgaagggaaggatcaaa
cacctggacgtggtcactctgctgcggcgcatccagcctccactgggctttgggaagttg
tgtccgcacagagtggcatgcaagagattagttgccatgaacatgcctctcaacagtgat
gggacggtcatgtttaatgcaactctctttgctttggttcgaacggctcttaagatcaag
acggaagggaacctggaacaagctaatgaagaactccgggctgtgataaagaaaatctgg
aagaaaaccagcatgaaactgctcgaccaagttgtccctccagctggtgatgatgaggta
accgtggggaagttctatgccactttcctgatacaggactactttaggaaattcaagaaa
cggaaagaacaaggactggtgggaaagtaccctgcgaagaacaccacaattgccctacag
gcaggattaaggacactgcatgacattgggccagaaatccggcgtgccatatcatgtgat
ttgcaagatgatgagcctgaggaaacaaaacgagaggaagaagaagatatattcaaaaga
aatggtgccctgcttggaaaccatgtcaatcatgttaatagtgataggagagattccctt
cagcagaccaataccacccaccgtcccctgcatgtccaaaggccttcaattccacctgca
agtgatactgagaaaccgctgtttcctccagcaggaaattcggtgtgtcataaccatcat
aaccataattccataggaaagcacgttcccacctcaacaaatgccaatctcaataatgcc
aatatgtccaaagctgcccatggaaagcggcccagccttgggaaccttgagcatgtgtct
gaaaatgggcatcattcctcccacaagcatgatcgggagcctcagagaaggtccagtatc
aaaagaacccgctattatgaaacttacattagatctgactcgggagatgagcagctccca
actatttgccgggaagacccagagatccatggctacttcagggacccccgctgcctgggg
gagcaggaatatttcagcagtgaggagtgctatgaggacgacagctcgccacccgggagc
aggcaaacctatggctactacagcaggtacacaggcagcaactcggacttcgagaggccc
cggggctaccatcacccccaaggcttcctggaggacgacgactcccccgtctgctatgac
tcacggagatctccaaggagacgcctactacctcccaccccaacatcccaccggagatcc
tccttcaacttcgagtgcctgcgccggcagagcagccaggaggaggtcccgctgtcgcct
gccttcccccaccgcacagccttgcctctgcacctgatgcagcaacagatcatggcagtt
gcaggcctagattctagtaaagcccagaagtactcgccgagtcactcaacccggtcgtgg
gccacccctccagcgacccctccgtaccgggactggacaccatgctacaccccgctgatc
caggtggaccggtcagagtccctggaccaggtcaacggcagcctgccgtccctgcaccgc
agctcctggtacacagatgagcccgacatctcctatcggactttcacaccagccagcctg
acggtccccagcagcttccgcaacaagaacagcgacaagcagaggagtgcggacagcttg
gtggaggcggtcctgatatctgaaggcttaggacgctatgcaagggacccaaaatttgtg
tcagcaacaaaacacgaaatcgccgatgcctgtgacctgaccatcgatgagatggagagt
gcggccagcaccctgctgaacggcagcgtgcatcgccgagccaacggggacgtgggcccc
gtctcacaccggcaggactacgagctccaggactttggtcccggctacagcgacgacgag
ccggacctagggagagacgaggaggacctggcagatgagatgatatgcatcaccaccttg
tag
DBGET
integrated database retrieval system
