Eulemur rufifrons (Bennett's brown lemur): 138389693
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Entry
138389693 CDS
T11398
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
eruf Eulemur rufifrons (Bennett's brown lemur)
Pathway
eruf04217
Necroptosis
eruf04380
Osteoclast differentiation
eruf04620
Toll-like receptor signaling pathway
eruf04621
NOD-like receptor signaling pathway
eruf04630
JAK-STAT signaling pathway
eruf04658
Th1 and Th2 cell differentiation
eruf04659
Th17 cell differentiation
eruf05145
Toxoplasmosis
eruf05160
Hepatitis C
eruf05161
Hepatitis B
eruf05162
Measles
eruf05164
Influenza A
eruf05165
Human papillomavirus infection
eruf05167
Kaposi sarcoma-associated herpesvirus infection
eruf05168
Herpes simplex virus 1 infection
eruf05169
Epstein-Barr virus infection
eruf05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
eruf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
138389693 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
138389693 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
138389693 (TYK2)
04621 NOD-like receptor signaling pathway
138389693 (TYK2)
04658 Th1 and Th2 cell differentiation
138389693 (TYK2)
04659 Th17 cell differentiation
138389693 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
138389693 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
138389693 (TYK2)
05160 Hepatitis C
138389693 (TYK2)
05171 Coronavirus disease - COVID-19
138389693 (TYK2)
05164 Influenza A
138389693 (TYK2)
05162 Measles
138389693 (TYK2)
05168 Herpes simplex virus 1 infection
138389693 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
138389693 (TYK2)
05169 Epstein-Barr virus infection
138389693 (TYK2)
05165 Human papillomavirus infection
138389693 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
138389693 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
eruf01001
]
138389693 (TYK2)
Enzymes [BR:
eruf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
138389693 (TYK2)
Protein kinases [BR:
eruf01001
]
Non-receptor tyrosine kinases
JAK family [OT]
138389693 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-GeneID:
138389693
NCBI-ProteinID:
XP_069334325
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Position
2:complement(11195499..11214861)
Genome browser
AA seq
1187 aa
AA seq
DB search
MPLCQRRSSRGSKPDENGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSDGSLTAEEVCIHI
AHKIGITPPCVNLFALYDAQAQVWLPPNHILEISSDTSLVLYFRMRFYFRNWHGMNPQEP
AVYRCGPPGTEASSEQTEQGVQLLDPASFEYLFEQGKHEFVNDVASLWELSNEEEIHHFK
NESLGMAFLHLCHLALHRGVPLEEVAKKISFKDCIPRSFRRQIRQHNVLTRLRLRSVFRK
FIRAFQPGLLSQQLVMVKYLATLERLAPRFGTERLPVCHLRLLAQAEVEPCYTLDSGQSP
ADPNPESAAGPSTHEVLVTGTGGIQWRPIQTEGSSGGGGSSNISGRNPHASLSGKKAKVH
EVGDPPVDRPQEPPWAYFCDFRDITHVVLKERRVSIHQQDNKCLELSLPSRAEALSFVSL
VDGYFRLTADSSHYLCHEVAPPRLVMSIQDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSH
LYRLILTVAQRGQSPGHAQSLHLRKFPIEQRAGAFVLEGWGRSFPSVRELRAALQGCWLR
AGNDSFSLHRCCLPRPGEISNLIVMRGPRASSRQLNLSQLSFHRVGQDKITQLSHLGQGT
RTNVYEGVLQVEGGDPEEGKVDGGDPLVPGGNSGQKLRVVLKVLDPSHHDIALAFYETAS
LMSQVSHVHLAFVHGVCVRGSENIMVTEYVEHGPLDVWLRRERGHVPVAWKVVVAQQLAS
ALSYLEDKNLVHGNVCGRNVLLARPGLAEGTSPFIKLSDPGVGLSALSREERVERIPWMA
PECLPGGANSLSTATDKWGFGATLLEICFDGEAPLQGRGPSEKERFYQKQHQLPEPSCPE
LATLTSQCLTYEPGQRPSFRTILRDLTRLQPHNLADVVTVNPDSPASDPTVFHKRYLKKI
RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQLRSGWRREIDILRTLYHEHIV
KYKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHAQHYI
HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYCVREDGDSPVFWYAPECLKDGKFYY
ASDVWSFGVTLYELLTHCDSSQSPPSKFIELIGHTQGQMTVLRLIELLERGERLPRPDRC
PPEIYLLMKNCWDTEASFRPTFQNLIPILKTVQEKYRSQAPSVFSVC
NT seq
3564 nt
NT seq
+upstream
nt +downstream
nt
atgcccctgtgccaacggcggagctccaggggcagcaagcccgatgagaacggagctcag
cctatggctgccatgggaggcctgaaggtgcttttgcactgggctggccctggtggtggg
gagccctgggtcaccttcagtgacggctcgctgaccgctgaggaggtctgcatccatatc
gcacacaaaatcggcataactcctccctgcgtcaatctctttgccctgtacgatgcccaa
gctcaagtctggctgcccccaaaccacatcctagagatctccagtgacacaagcctggtg
ctgtatttccgcatgaggttttatttccggaactggcatggcatgaatcctcaggagcca
gctgtgtaccgctgcgggcccccaggcaccgaggcttcctcagaacagacagagcagggg
gtgcaactcctggacccagcctcatttgagtacctctttgagcagggcaagcacgagttt
gtgaatgatgtagcatcactgtgggagctctcaaacgaagaggagatccaccactttaag
aatgagagcctgggcatggcttttctgcacctctgccaccttgccctccaccgcggtgta
cccctggaggaggtggccaagaagatcagcttcaaggactgcatcccacgctccttccgg
aggcagatccggcagcacaacgtgctgacgcggctgcgcctgcgcagtgttttccgcaag
ttcatccgggcctttcagccaggcctcctctcccagcaattggtcatggtcaaatacctg
gccacactggagcggctggcgccccgctttggcacggagcgcctgccggtgtgccacctg
aggctgctggcccaggccgaagttgagccctgctacaccctggacagcgggcagtccccc
gcggaccccaaccctgagtctgcagctgggccctccacccacgaggtgctggtgacaggc
accggcggcatccagtggcgccctatacaaacggagggctctagtggtggcggtggcagc
agcaacatcagtggcaggaatccccacgccagcctgtctgggaagaaagccaaggtacac
gaggtgggggacccaccagtggacaggccgcaagagccaccatgggcctacttctgcgac
ttccgggacatcacccacgtggtgctcaaagaacgccgtgtcagcatccatcagcaggac
aacaagtgcctggaactcagcctgccctcccgggccgaggccctgtccttcgtgtcgctc
gtggatggctatttccgcctgacagctgactccagtcactacctgtgccacgaggtggcc
ccaccacggctggtgatgagcattcaggatggcatccacggccccttgctggagccgttt
gtgcaggccaagctgcggcccgaggacggcctgtacctcatccactggagcaccagccac
ctctaccgcctcatcctcacagtggcccagcgtggccagtcacctggccacgcacagagc
ctgcacctccgcaagttccccattgagcagcgggctggggccttcgtgctggagggctgg
ggccgctccttccccagcgtgcgggagctgcgggccgccttacagggctgctggctgcgg
gctgggaacgacagcttctctttgcaccgctgctgcctgccacggccgggagaaatctcc
aacctcatcgtcatgcgggggcctcgggccagcagcaggcagctcaacctcagccagctc
agcttccaccgagtcggccaggacaagatcactcagctgtcccacttgggccagggcacg
aggaccaacgtgtatgagggcgtcctgcaagtggagggcggggaccccgaggagggcaaa
gtggacggcggggaccccctcgtgcccggtgggaactctgggcagaagctacgagtggtg
ctcaaagtgctggatcctagtcaccatgacattgccctggccttctacgagacggccagc
ctcatgagccaggtgtcccacgtgcacctggcctttgtgcacggcgtctgtgtgcgcggc
tctgagaacatcatggtgacggagtatgtggaacatgggcccctagatgtgtggctgcgg
cgagagagaggccacgtgcctgtggcctggaaggtggtggtcgcccagcagctggccagt
gccctcagctacttggaggacaagaacttggttcatggtaacgtgtgtggccggaacgtc
ctgctggcacggcctgggctggcagaaggcaccagccccttcatcaagctgagtgaccca
ggcgtgggcctgagtgccctctccagggaggagcgggtggagcggatcccgtggatggcc
cctgagtgtctgcccggcggagccaacagcctgagcaccgccaccgacaagtggggcttt
ggtgccaccctcctagagatctgcttcgatggggaagccccccttcagggccgaggcccc
tccgagaaagagcgtttctaccagaagcagcaccagctgcctgagccctcgtgccccgaa
ctggccacgctcaccagtcagtgcctgacctacgagccaggccagaggccgtcattccgc
accatcctgcgcgacctcactcggctgcagccacacaatcttgctgacgttgtgactgtg
aaccccgactccccggcgtcggaccccacggttttccacaagcgctatttgaaaaagatc
cgggatttgggcgagggtcactttggcaaggtcagcttgtactgctacgacccgaccaac
gacggcactggcgagatggtggccgtgaaagccctcaaggcggactgcggcccccagctc
cgctccggctggaggcgggagatagacatcctgcgcacgctctatcacgagcacatcgtc
aagtacaagggctgctgcgaggaccaaggcgagaagtcggtgcagctcgtcatggagtac
gtgcccctgggcagcctccgagactacctgccccggcacagcgtcgggctggcccagctg
ctgctcttcgcccagcagatctgtgagggcatggcctacctgcacgcgcagcactacatc
caccgagacctcgctgcgcgcaacgtgctgctggacaacgacaggctggtcaagataggg
gactttggcctagccaaggcggtgcccgaaggccacgagtactactgcgtgcgcgaggat
ggggacagccccgtgttctggtatgccccagaatgcctgaaggacggtaagttctactat
gcgtccgacgtctggtccttcggggtcaccctgtatgagctgctaacacactgcgactcc
agccagagccccccctcgaaattcatcgagctcataggccacacccagggccagatgacg
gtgctgagactcatagagctgctggaacgaggggaaaggctgccccggcctgacagatgt
ccccccgagatctatcttctcatgaagaactgctgggacacagaagcctccttccgcccc
accttccagaacctcatacccatcctcaagacagtccaggagaaataccgaagccaggcc
ccttcggtgttcagtgtgtgctga
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