Eulemur rufifrons (Bennett's brown lemur): 138392196
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Entry
138392196 CDS
T11398
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
eruf Eulemur rufifrons (Bennett's brown lemur)
Pathway
eruf04140
Autophagy - animal
eruf04141
Protein processing in endoplasmic reticulum
eruf04210
Apoptosis
eruf04932
Non-alcoholic fatty liver disease
eruf05010
Alzheimer disease
eruf05012
Parkinson disease
eruf05014
Amyotrophic lateral sclerosis
eruf05016
Huntington disease
eruf05017
Spinocerebellar ataxia
eruf05022
Pathways of neurodegeneration - multiple diseases
eruf05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
eruf00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
138392196 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
138392196 (ERN1)
09143 Cell growth and death
04210 Apoptosis
138392196 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
138392196 (ERN1)
05012 Parkinson disease
138392196 (ERN1)
05014 Amyotrophic lateral sclerosis
138392196 (ERN1)
05016 Huntington disease
138392196 (ERN1)
05017 Spinocerebellar ataxia
138392196 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
138392196 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
138392196 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
138392196 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
eruf01001
]
138392196 (ERN1)
Enzymes [BR:
eruf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
138392196 (ERN1)
Protein kinases [BR:
eruf01001
]
Serine/threonine kinases: Other
IRE family
138392196 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-GeneID:
138392196
NCBI-ProteinID:
XP_069338879
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All DBs
Position
9:complement(43392358..43471528)
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AA seq
976 aa
AA seq
DB search
MPARLLLLLLLALLLPGSGIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKED
PVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSTDGILYMG
KKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATY
FDYAASLPEDDMDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRK
VMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSM
VHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKSKNKLNYLRNYW
LLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQASENAPTTVS
QDVEEKPAHAPAKPEAPVDSMLKDMATIILSTFLLVGWVAFIITYPLSMHQQRQLQRQQF
QKELEKIQLLHQQQLPFPPPGDATQDGEFLDTSGAYSESSGTSSPSTSPRASNHSLCSGS
SASRAGTSPFLEQDDEDEETSVVMVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRI
LPECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHL
GLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVG
RHSFSRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGSHPFGKSLQR
QANILLGAYSLDCFHPEKHEDVVARELIEKMIAMDPQKRPSAKHVLKHPFFWSLERQLQF
FQDVSDRIEKEPLDGPIVKQLERGGRAVVKLDWRENITVPLQTDLRKFRTYKGGSVRDLL
RAMRNKKHHYRELPDEVRETLGSLPDDFVCYFTSRFPHLLLHTYRAMELCGHERLFQPYY
SQEPPEPQPPVTPDTH
NT seq
2931 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggctgctgctcctgctgctgctggcgctgttgctgcccggctctgggatt
tttggaagtaccagcacagtgacgcttcctgaaaccttattgtttgtgtcaaccctggat
ggaagtttgcatgctgtcagcaagaggacaggctcaatcaaatggactttaaaagaagat
ccagtcttgcaggtcccaactcatgtggaagagcccgccttcctccccgatcccaatgat
ggcagcctatacacacttgggggcaagaataatgaaggtctgacaaaacttccatttacc
atcccagagttggtgcaggcatcgccatgccgaagtacagacggaatcctctacatgggt
aaaaagcaggacatttggtatgttattgaccttctgactggggagaagcagcagactttg
tcatcggcctttgcagacagtctgtgcccatcaacctctcttctgtatcttgggcgaaca
gaatataccatcaccatgtatgacaccaaaacccgggaactccggtggaacgccacctac
tttgactatgcagcctcactgcccgaggacgacatggactataagatgtcccactttgtg
tccaatggcgacgggctggtggtaaccgtggacagtgaatctggggacgtcctgtggatc
caaaactatgcctcccctgtggtggccttctatgtctggcaacgggagggtctgcggaag
gtgatgcacatcaacgtcgccgtggagaccctgcgctacctgaccttcatgtcgggggag
gtggggcgcatcaccaagtggaagtacccgttccccaaggagacggaggccaagagcaaa
ctgacgcccaccctgtacgtcgggaaatactctaccagcctctatgcctccccctccatg
gtacacgagggagttgctgtcgtgccccgtggcagcactctccctttgctggaaggcccc
cagactgatggcgtcaccattggggacaaaggggagtgtgtgatcacgcccagcaccgac
ctcaagttcgaccctggactcaaaagcaagaacaagctcaactacttgaggaattactgg
ctcctgataggacaccatgaaaccccactgtctgcgtctaccaagatgctggagagattt
cccaacaatctgcccaaacatcgggaaaatgtgattcctgctgattcagagaaaaagagc
tttgaggaagttatcaacctggtggaccaggcttcggaaaatgcacccaccaccgtgtct
caggacgtggaagagaagcctgcccacgcccccgccaagcccgaggcccccgtggactcc
atgctcaaggacatggccaccatcatcctcagcaccttcctgctggtcggctgggtggcc
ttcatcatcacctaccccttgagcatgcatcagcagcggcagctccagcgccagcagttc
cagaaggaactggagaaaatccagctcctgcaccagcagcagctgcccttccccccacct
ggggacgccactcaggatggcgagttcctggacacgtctggcgcgtactcggagagctcg
ggcaccagcagccccagcacgtctcccagagcctccaaccattcgctctgctccggcagc
tctgcctccagggctggcaccagccccttcctggagcaggacgacgaggatgaggaaacc
agcgtggtgatggttgggaagatttcattctgtcccaaggatgtcctgggccatggagct
gagggcacaatcgtgtaccggggcatgtttgacaaccgagacgtggccgtgaagaggatc
ctccccgagtgcttcagcttcgcagaccgcgaggtgcagctgctgcgagagtcggacgag
cacccgaacgtgatccgctacttctgcacggagcgcgaccgccagttccagtacatcgcc
atagagctgtgcgcggccaccctgcaagagtacgtggagcagaaggactttgcccacctt
ggcctggagcccatcaccctgctgcagcagaccacctcgggcctggcccacctccactcc
ctcaacatcgttcacagagacctgaagccccacaacatcctcctctctatgcccaatgca
cacggcaggatcaaggccatgatctccgactttggcctctgcaagaagctggcggtgggc
aggcacagcttcagccgccgttctggggtgcctggcacggaaggctggattgctcccgag
atgctgagtgaagactgcaaggacaaccctacctacacggtggacatcttctctgcaggc
tgcgtcttttactatgtgatctctgagggcagccaccctttcggcaagtccctgcagcgg
caggccaacatcctcctgggcgcctacagcctcgactgcttccaccccgagaagcatgaa
gatgtcgttgcgcgtgaactaatagagaaaatgatcgcgatggatccacagaaacgcccc
tcggcgaagcacgtgctgaaacatccgtttttctggagcctggagaggcagcttcagttc
tttcaggacgtgagcgaccggatagagaaggagccgctggacggcccgatagtgaagcag
ctggaacgcggcggcagagccgtggtgaagctggactggcgggagaacatcaccgtcccc
ctccagacagatctgcgtaaattcagaacctacaagggcggctctgtcagggacctgctc
cgcgccatgagaaataagaagcaccactaccgggagctccccgacgaggtgcgggagacg
ctgggctccctcccagatgacttcgtgtgctacttcacgtcgcgcttcccccacctcctc
ttgcacacctaccgggccatggagctgtgcggccacgagagactcttccagccctactac
tcccaggagcccccggagccccagccccccgtgaccccagacacccactga
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