Eulemur rufifrons (Bennett's brown lemur): 138392220
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Entry
138392220 CDS
T11398
Symbol
IDH1
Name
(RefSeq) isocitrate dehydrogenase [NADP] cytoplasmic
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
eruf Eulemur rufifrons (Bennett's brown lemur)
Pathway
eruf00020
Citrate cycle (TCA cycle)
eruf00480
Glutathione metabolism
eruf01100
Metabolic pathways
eruf01200
Carbon metabolism
eruf01210
2-Oxocarboxylic acid metabolism
eruf01230
Biosynthesis of amino acids
eruf04146
Peroxisome
eruf05230
Central carbon metabolism in cancer
Module
eruf_M00009
Citrate cycle (TCA cycle, Krebs cycle)
eruf_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
eruf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
138392220 (IDH1)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
138392220 (IDH1)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
138392220 (IDH1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
138392220 (IDH1)
Enzymes [BR:
eruf01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
138392220 (IDH1)
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NCBI-GeneID:
138392220
NCBI-ProteinID:
XP_069338976
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Position
1:25582819..25602077
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AA seq
414 aa
AA seq
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MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATQDQVTKDA
AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEDGGGVAM
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNKELGFFAKALE
EVCIETIEAGFMTKDLAICIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
NT seq
1245 nt
NT seq
+upstream
nt +downstream
nt
atgtccaaaaaaatcagtggtggttccgtggtagagatgcaaggagatgaaatgacacga
atcatttgggaattgattaaagaaaaactcatttttccctatgtggaattggatctgcat
agctatgacttaggcatagagaatcgtgatgccacccaagaccaagtcacaaaggatgct
gcagaggccataaagaaatacaatgtgggcgtcaagtgtgctactatcacccccgatgag
aagagggttgaggaattcaagttgaaacaaatgtggaagtcaccgaacggcaccatccga
aatattctgggtggcactgtcttcagggaagctattatctgcaaaaatatcccccggctt
gtgagtggatgggtgaaacccatcatcataggtcgtcatgcttatggggaccaatacaga
gcaaccgattttgttgttccggggcctggaaaagtagagataacctacacaccaagtgat
ggaacccaaaaggtgacatacttggtacataactttgaagatggtggtggtgttgccatg
ggtatgtataatcaagataagtcaatcgaagattttgcacatagttccttccaaatggct
ctgtctaagggttggcctttgtatctgagcaccaaaaacactattctgaagaaatatgat
ggacgttttaaagacatctttcaggagatatatgacaagcagtacaaatcccaatttgaa
gcccagaatatctggtatgagcataggctcattgatgacatggtggcccaagctatgaaa
tcagagggaggcttcatctgggcctgtaaaaactatgacggtgatgtgcagtcggactcc
gtggcccaaggttatggctctcttggcatgatgaccagtgtgctgatttgtccagatggc
aaaacagtagaagcagaggctgcccacgggaccgtaacccgtcactaccgcatgtaccag
aaaggacaggagacgtccaccaatcccattgcttccatttttgcctggagcagagggttg
gcccacagagcaaagcttgataacaataaagagcttggcttctttgcaaaggccttggaa
gaagtctgtatcgagaccattgaggctggcttcatgaccaaggacttggctatttgcatt
aaaggtttacctaacgtgcaacgttctgactacttgaatacatttgaattcatggacaaa
cttggagaaaacttgaagataaaactagctcaggccaaactttaa
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