Escherichia ruysiae: OSH18_09570
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Entry
OSH18_09570 CDS
T09019
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
eruy
Escherichia ruysiae
Pathway
eruy00260
Glycine, serine and threonine metabolism
eruy00261
Monobactam biosynthesis
eruy00270
Cysteine and methionine metabolism
eruy00300
Lysine biosynthesis
eruy01100
Metabolic pathways
eruy01110
Biosynthesis of secondary metabolites
eruy01120
Microbial metabolism in diverse environments
eruy01230
Biosynthesis of amino acids
Module
eruy_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
eruy_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
eruy_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
eruy00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
OSH18_09570 (thrA)
00270 Cysteine and methionine metabolism
OSH18_09570 (thrA)
00300 Lysine biosynthesis
OSH18_09570 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
OSH18_09570 (thrA)
Enzymes [BR:
eruy01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
OSH18_09570 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
OSH18_09570 (thrA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
DUF6247
Motif
Other DBs
NCBI-ProteinID:
WGM54331
LinkDB
All DBs
Position
complement(2008477..2010939)
Genome browser
AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTISGQDA
LPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHYLESTVDIAESTRRIAASRIP
ADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGNPQAPGTLIGASRD
EDELPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRARISVVLITQSSSEYSISF
CVPQSDCARAERAMQEEFYLELKEGLLEPLAVTERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVNNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGAL
LEQLKRQQSWLKNKHIDLRVCGVANSKALLTNVHGLNLENWQEELAQAKEAFNLGRLIRL
VKEYHLLNPVIVDCTSSQEVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRYAAEKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLA
REMGYTEPDPRDDLSGMDVARKLLILARETGRELELADIEIEPVLPAEFNAEGDVAAFMV
NLSQLDDLFAARVAKARDEGKVLRYVGNIDDDGVCRVKIAEVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagttcggcggtacatcagtggcaaatgcggaacgttttctgcgggtt
gccgatattctggagagcaatgccaggcaggggcaggtggctacagtcctctctgctccc
gccaaaataaccaaccatctggtggcgatgattgaaaaaacgattagcggccaggatgct
ttgcccaatatcagcgatgccgaacgtatttttgccgaacttctgacgggactcgccgcc
gcccagccgggatttccgctggcgcaactgaaaacgttcgtcgatcaagaatttgcccaa
attaaacatgttctgcatggtatcagcctgttgggacagtgcccggacagcatcaacgct
gcgctcatctgccgtggtgaaaaaatgtcgatcgccattatggccggtgtactggaagcg
cgcggacataacgttaccgttatcgatccagtcgaaaaactgctggcagtcggtcattac
ctcgaatctaccgtcgatattgctgagtccacccgccgtattgcggcaagccgcattccg
gctgaccacatggtgctgatggcaggtttcaccgccggtaatgaaaaaggcgaactggtg
gtgctgggacgtaacggttccgactactccgctgcggtactggccgcctgtttacgtgcc
gattgttgcgagatctggacggacgttgacggtgtctatacctgcgacccgcgtcaggta
cccgatgcgagattgttgaagtcgatgtcctaccaggaagcaatggagctttcctacttc
ggcgctaaagttcttcacccccgcaccattacccccatcgcccagttccagatcccttgc
ctgattaaaaacaccggaaatccacaagcgcccggtacgctcattggcgccagccgtgat
gaagatgagctgccggtcaaaggtatttctaacctgaataacatggcgatgttcagcgtt
tcaggtccaggaatgaaagggatggtcggcatggcggcgcgcgtctttgcggcgatgtca
cgcgccagaatttcagtggtgctgattacgcaatcgtcttccgaatacagtatcagtttc
tgcgtaccacaaagcgactgtgcgcgtgctgaacgggcgatgcaggaagagttctatctt
gaactgaaagaaggcttactggagccgctggcggtgacggaacggctggccattatctcg
gtggtgggcgatggtatgcgcacgctgcgtgggatctcggcgaaattctttgccgctctg
gcccgcgccaatatcaacattgtcgccattgcccaagggtcttctgaacgttcaatttct
gtcgtggtaaataacgatgacgcgacgactggcgtgcgcgttacccaccagatgctgttc
aataccgatcaggttatcgaagtgtttgtgattggcgtcggtggcgttggcggcgcgctg
ctggagcaactgaagcgtcagcaaagctggctgaagaacaaacatattgatttacgagtc
tgtggcgttgccaactcgaaggcgttgctgactaatgtgcatggcctcaacctggaaaac
tggcaggaagaactggcgcaagccaaagaggcgttcaaccttgggcgcttaattcgcctg
gtgaaagaatatcatctgctgaacccggtcattgttgactgcacctccagccaggaggtg
gcggatcaatatgccgacttcctgcgcgaaggtttccacgttgtcacgccgaacaaaaag
gccaacacctcgtcgatggattactaccaccagttgcgttatgcggcggaaaaatcgcga
cgtaaattcctctatgacaccaacgtcggtgcgggattaccggtcattgagaatctgcaa
aacctgctcaatgcaggtgatgagttgatgaaattctccggcattctttctggttcgctt
tcatacatcttcggcaagctagacgaaggcatgagtttctctgaggcgaccacgctggcg
cgggaaatggggtataccgaaccggatccgcgtgatgatctttctggtatggatgtggcg
cgcaaactgttgattctcgcccgtgaaactggacgtgaactggagctggcggatatcgag
atcgaacctgtgctgcccgcagagtttaacgcagagggtgatgttgcagcttttatggtg
aatctgtcacagctcgacgatctctttgccgcgcgcgtggcgaaggctcgtgatgagggt
aaagttttgcgctatgttggcaatattgatgacgatggcgtctgccgcgtgaaaattgct
gaagtggacggtaacgatccgctgttcaaagtgaaaaatggcgaaaacgctctggccttc
tatagccactattatcagccgctgccgttggttctgcgcggatacggcgcgggcaatgac
gttacggctgccggtgtctttgccgatctgctacgcaccctctcatggaagttaggagtc
tga
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