Escherichia ruysiae: OSH18_18775
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Entry
OSH18_18775 CDS
T09019
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
eruy
Escherichia ruysiae
Pathway
eruy00230
Purine metabolism
eruy01100
Metabolic pathways
eruy01110
Biosynthesis of secondary metabolites
Module
eruy_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
eruy00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
OSH18_18775 (purL)
Enzymes [BR:
eruy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
OSH18_18775 (purL)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-ProteinID:
WGM52213
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Position
3932554..3936441
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AA seq
1295 aa
AA seq
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MMEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLNAPLNDDEHAQLERLLK
YGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYVEAGTLT
NDQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGL
ALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFKM
IKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHETGRYDYHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI
RADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL
EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDL
PLDVLLGKTPKMTRDVQTLKAKGDALAREGITIADAVKRVLHLPTVAEKTFLVTIGDRSV
TGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEAL
TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS
MKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGA
TALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFA
GHCGIEADIATLGEDRLAALFNEELGAVIQVRAADREAVEAVLAQYGLADCVHYVGQAVS
GDRFVITANRQAVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVK
LSFDINEDVAAPFIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRT
GLEDFHALVACGGFSYGDVLGAGEGWAKSILFNNRVRDEFATFFHRPQTLALGVCNGCQM
MSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGR
VEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPH
PERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattctgcgtggttcgcctgcattgtcggcattccgaatcaacaaactgctg
gcacgttttcaggctgccaggctcccggttcacaacatttacgccgagtatgtccatttt
gctgacctcaatgcgccgttaaacgatgatgagcacgcacaacttgaacgcctgctgaaa
tatggcccggcactcgccagccacgccccgcaaggtaaactcctgctggtgaccccgcgt
ccaggcaccatctctccctggtcttcgaaagcgaccgatatcgcccataactgcgggctg
caacaggtaaaccgccttgagcgcggcgttgcttactatgtagaagccggtacgctgacc
aatgaccaatggcagcaggttaccgctgaactgcacgaccgcatgatggaaacggtcttt
ttcgctttagatgatgcagagcagctgtttgctcatcatcaaccgactccggttaccagc
gttgatttgctggggcaggggcgtcaggcgctaatcgacgctaacctgcgtcttggcctg
gcactggcggaagatgaaattgactatctgcaggatgctttcacgaagcttggtcgtaac
ccgaacgacatagagctttatatgttcgcccaggcgaactctgagcactgccgtcataag
atttttaacgccgactggattatcgacggtgaacagcagccgaaatcgctgttcaagatg
atcaaaaacaccttcgaaaccacgccggatcacgttctctctgcttataaagataacgcc
gccgtaatggaaggttctgaagtgggccgctactttgctgaccacgaaacaggtcgctac
gactatcatcaggaaccggcgcacatcctgatgaaagtagaaacccacaaccacccgacg
gcgatttctccgtggccgggcgcggcgactggttccggcggcgaaatccgtgatgaaggc
gcaaccggacgcggcgcgaagccgaaagccggcctggtcggtttctccgtatccaacctg
cgtatccctggctttgaacagccgtgggaagaagatttcggtaagcctgaacgtattgtt
actgcactggatatcatgaccgaaggcccgctgggcggcgcggcgtttaacaatgaattt
ggtcgtccggcactgaacggctatttccgtacgtatgaagaaaaagtgaacagccacaac
ggcgaagagctgcgcggttatcacaaaccgatcatgctggcgggcgggatcggcaatatt
cgcgccgatcacgtacaaaaaggtgagatcaacgtcggcgcgaagctggtcgttctcggc
ggcccggcaatgaacatcggccttggcggcggcgcggcgtcttccatggcgtctggtcag
tctgatgccgacctcgattttgcttccgtacagcgcgataacccggagatggagcgtcgt
tgccaggaagtgatcgaccgttgctggcagttgggtgatgccaacccaattctgtttatc
catgacgttggcgcgggcggtctttctaacgccatgccggaactggtgagcgacggcgga
cgcggcggtaaattcgaactgcgcgatattctgagcgatgaaccgggcatgagcccgctg
gaaatctggtgtaacgaatcccaggaacgctacgtgctggcggttgcagccgatcagtta
ccgctgtttgacgaattgtgtaaacgtgaacgtgcgccatacgcggtgattggtgaagcg
accgaagaactgcatctttctctgcacgatcgtcattttgataatcagccaatcgatctg
ccgctggacgtgctgcttggcaaaacgccgaagatgacccgcgatgtacaaacgctgaaa
gcgaagggcgatgcgctggctcgtgaagggatcaccattgctgacgcggtgaaacgcgtg
ctgcatctgccgactgtggcagagaaaaccttccttgtgaccattggcgaccgcagcgta
accggcatggtggcgcgcgatcagatggtgggtccgtggcaggtgccggtcgctaactgc
gcggtcactaccgccagcctcgacagctattacggtgaagcgatggcaattggcgaacgt
gcgccggttgcgctgctggatttcgccgcctctgcccgtctggcagttggtgaagcgtta
accaacatcgccgctacgcagattggcgatatcaaacgcatcaaactttccgccaactgg
atggcggctgcaggtcatcctggcgaagatgcgggtctgtatgaagccgtaaaagcggtg
ggtgaagagctttgcccggcgctcggcctgactattccggtgggtaaagactccatgtcg
atgaaaacccgctggcaggaaggtaacgaagagcgcgaaatgacgtcgccgctgtcgctg
gtgatttctgcatttgcccgcgtggaagatgtacgtcacaccatcacgccacagctttct
accgaagataacgcactattgctgattgatttgggcaaaggcaataacgcgctgggcgca
acggcgctggcgcaggtttatcgtcagcttggcgacaaaccggcagatgtacgcgatgtc
gcgcaactgaaaggcttctatgacgcgattcaggcgctggttgcacagcgtaagctgctg
gcgtatcacgaccgctctgatggcggtctgttggtaacgctggcggaaatggcgtttgcc
ggtcattgcggtattgaagcggatatcgccactctgggtgaagatcgcctggcggcgttg
tttaacgaagagctgggggcagtgattcaggtacgtgccgctgaccgtgaagcggtcgaa
gccgtactggcacagtatggccttgctgattgcgtccattatgtcggccaggcggtatct
ggcgaccgttttgtgattaccgccaacaggcaggctgtattcagcgaaagccgtactacg
ttgcgtgtctggtgggcagaaaccacctggcagatgcagcgcctgcgtgacaacccggag
tgtgccgatcaggagcatcaggcgaaatctaatgacgccgatccggggctgaatgtgaaa
ttgtcgttcgatatcaacgaagatgtggcggcaccgtttattgctactggcgcgcgcccg
aaagttgccgtactgcgtgagcagggcgtgaactcgcatgtggaaatggcggcagcgttc
caccgtgcgggcttcgatgctatcgacgtgcatatgagcgacctgctggctggacgcacg
ggcctggaggatttccacgctctggtggcgtgcggtggtttctcctacggtgatgtgctg
ggtgccggtgaaggttgggcgaagtctatcctgttcaataatcgtgtacgcgatgagttt
gcaaccttcttccaccgtccgcaaacgctggcgctgggggtatgtaacggttgccaaatg
atgtctaatctgcgtgaactgatcccgggtagcgagttgtggccacgttttgtgcgtaac
acctccgatcgctttgaagcgcgtttcagcctggtagaagtaacccaaagcccgtcgctg
ctgttgcaggggatggtgggttcacagatgccgattgccgtttctcacggtgaagggcgt
gttgaagtacgcgatgcggcgcatctggcagcactggaaagcaaagggctggtggcgctg
cgttatgtcgataacttcggcaaggtcaccgaaacttacccggctaacccgaacggttcc
ccgaacggtattacggcggtcacgactgaaagcgggcgtgtcaccattatgatgccacac
ccggagcgtgttttccgtactgtcagtaactcctggcatccggaaaactggggcgaggat
ggtccgtggatgcgtattttccgcaatgcgcgtaagcagctggggtaa
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