Erwinia sp. E602: GKQ23_21650
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Entry
GKQ23_21650 CDS
T10706
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
erwe Erwinia sp. E602
Pathway
erwe00290
Valine, leucine and isoleucine biosynthesis
erwe00620
Pyruvate metabolism
erwe01100
Metabolic pathways
erwe01110
Biosynthesis of secondary metabolites
erwe01210
2-Oxocarboxylic acid metabolism
erwe01230
Biosynthesis of amino acids
Module
erwe_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
erwe00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
GKQ23_21650 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
GKQ23_21650 (leuA)
Enzymes [BR:
erwe01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
GKQ23_21650 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
QUG77441
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Position
4382849..4384525
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AA seq
558 aa
AA seq
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MLPHPAEKYRPFPALTLPDRQWPGRTLRQAPRWLSTDLRDGNQSLAEPMDAERKMLFWQL
LLQCGFKEIEVAFPSASLTDFNFVRQLIGQRMIPQDVTIQVLTQARSDLIDRTFAALEGV
DRAIVHLYNATAPVFRRLVFRQSREQIIELAVSAARQIRQRCEEQPQTRWTFEYSPETFC
FTEMEFALQICEAVAAVWQPCDARPMIINLPATVEVSTPNVYADQIEYFCRHFSQRRQVC
ISVHPHNDRGTGIAAAELALLAGADRVEGCLFGNGERTGNVDLVTMALNFYTQGIAPGLD
FSQMKRVVDVVEQCNQLPVHPRHPYAGELVFTAFSGSHQDAIKKGFAARKLQQEPHWEVP
YLPLDPADIGCSYEAVIRVNSQSGKSGAAWMIEQNHGLTLPRGLQQDFSQRVQQVTDGDS
KEMTQAAIWQLFRQAYGLDAPALRLNDYRSQSDHHGQLQFAASVQRGEQAIVISGCGNGL
LSAAVDALRQAFDVPFAIQDYHEHTLGQRSDSRSVAYLRCTFGDNRSLWGVGIDSDVSRA
SLQALLNALGQALSAAGK
NT seq
1677 nt
NT seq
+upstream
nt +downstream
nt
atgctgccacatcccgccgaaaaatatcgcccctttcccgccctgacgctgccagaccgc
cagtggcccggccgcaccctgcgccaggcaccgcgctggctctccaccgatctgcgcgac
ggcaaccagtcgctggcggaaccaatggacgccgaacgcaaaatgctgttctggcagctg
ctgctgcagtgcggctttaaagagatcgaggtcgcctttccgtcggcctcgctgaccgat
ttcaactttgtgcgccagctgatcgggcagcggatgatcccgcaggacgttaccatccag
gtgctgacccaagcgcgatcggatctgatcgatcgtaccttcgccgcgctggaaggggtg
gatcgggcgatcgtccatctgtataacgccaccgcgccggtatttcgccggctggtgttc
cgccagagccgtgaacagattatcgaactggccgtcagcgccgcccgccagatccgccag
cgttgcgaagagcagccgcagacccgctggaccttcgaatactcgcccgaaaccttctgc
tttaccgaaatggagtttgccctgcagatctgtgaagcggtggccgccgtctggcagccc
tgcgacgcacgcccaatgattatcaacctgccggccaccgtggaggtcagcacgccgaac
gtctatgccgatcagattgagtacttctgccgccacttctcgcagcgccggcaggtgtgc
atcagcgtgcatccgcataacgatcgcggcaccggcattgccgccgccgagctggcgctg
ctggcgggggctgaccgggtggagggctgcctgtttggcaacggcgaacgcaccggcaac
gtcgatctggtgaccatggcgctgaacttttatacccaggggatcgcccccgggctggat
ttcagccagatgaaacgggtggtggacgtggtggagcagtgtaaccagctgccggtgcat
ccgcgccacccttacgcgggagagctggtgtttaccgcgttttccggctcccaccaggat
gcgattaagaagggctttgccgcgcgtaaactgcagcaggagccgcactgggaagtgccc
tatctgccgctcgatccggcggatatcggctgcagctatgaagcggtgatccgcgttaac
agccagtcgggcaagagcggtgccgcctggatgatcgaacagaatcatggcctgaccctg
ccgcgcggcctgcagcaggatttcagccagcgggtgcagcaggtcaccgacggcgacagc
aaagagatgacccaggcggcgatctggcagctgttccgccaggcgtatggcctggatgcc
ccggccttacgcctgaacgactaccgcagccagagcgaccaccacgggcagctgcagttt
gcggccagcgtgcagcgcggtgagcaggcgatcgtcatcagcggctgcggcaacgggctg
ctgtcggccgcggtagacgcgctgcgccaggcgttcgacgtcccctttgccattcaggac
taccatgagcacaccctcggccagcgtagcgacagccgttccgttgcctatctgcgctgc
accttcggcgacaaccgcagcctgtggggcgtcggcatcgacagcgacgtgtcacgcgcg
tcgctgcaggcgctgctcaacgcgctggggcaggctctgtccgccgcagggaaatga
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