Escherichia sp. F1: ACK8NJ_19420
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Entry
ACK8NJ_19420 CDS
T11101
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
esf Escherichia sp. F1
Pathway
esf00300
Lysine biosynthesis
esf00550
Peptidoglycan biosynthesis
esf01100
Metabolic pathways
esf01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
esf00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ACK8NJ_19420 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ACK8NJ_19420 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ACK8NJ_19420 (murF)
Enzymes [BR:
esf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ACK8NJ_19420 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
ADH_zinc_N
Motif
Other DBs
NCBI-ProteinID:
XMR20320
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Position
complement(4045325..4046683)
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AA seq
452 aa
AA seq
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MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAG
GAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS
PNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATL
DAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD
MAELGAESEACHIQVGEAAKAAGIDRVLSVGKQSHAISTASGVGEHFSDKTALIARLKSL
ITEQQVITILVKGSRSAAMEEVVRALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcgtaacccttagccaacttaccgatattctcaacggtgaactgcaaggtgca
gatatcacccttgatgctgtaaccactgacacgcgaaaactgacgccgggctgcctgttt
gttgccctgaaaggcgaacgtttcgatgctcatgattttgccgaccaggcgaaagctggc
ggcgcgggcgcactactggtcagccgtccgctggatatcgatctgccgcagttaatcgtc
aaggatacgcgtctggcgtttggtgaactggctgcatgggttcgccagcaagttccggcg
cgcgtggttgctctgacgggctcctccggcaaaacctctgttaaagagatgacggcggca
attttaagccagtgtggcaacacgctttatacggcaggcaatctcaacaacgacatcggc
gtgccgatgacgctgttgcgcttaacgccggaatacgattacgcagttattgaacttggc
gcgaaccatcagggcgaaattgcctggactgtgagtctgactcgcccggaagcggcgctg
gtcaataacctggcggcagcgcatctggaaggtttcggttctttggctggcgtggcaaaa
gcgaaaggcgaaatctttagcggcttgccggaaaacggtatcgccattatgaatgccgac
aacaacgactggctgaactggcagagcgtaattggctcacgcaaagtgtggcgtttctca
cccaatgccgccaacagcgatttcaccgccaccaacatccatgtgacttcgcacggtacg
gaatttaccctgcaaaccccaaccggtagcgtcgatgttctgctgccgcttccagggcgt
cacaatattgcgaatgcgctggcagccgctgcgctctccatgtccgtgggcgcgacgctt
gatgctatcaaagcggggctggcaaatctgaaagctgttccaggccgtctgttccccatc
cagctggcggaaaaccagttgctgctcgacgactcctacaacgccaatgtcggttcaatg
accgcagcagtccaggtactggctgaaatgccgggctaccgcgtgctggtggtgggcgat
atggcggaactgggcgctgaaagcgaagcctgccatatacaggtgggcgaagcggcaaaa
gcagctggtattgaccgcgtgttaagcgtgggtaaacaaagccatgctatcagcaccgcc
agcggcgttggcgaacatttttccgataaaactgcgcttatcgcgcgtcttaaatcactg
attactgagcaacaggtaattacgattttagttaagggttcacgtagtgctgccatggaa
gaggtagtacgcgctttacaggagaatgggacatgttag
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