Euwallacea similis: 136409008 Help Entry 136409008         CDS       T10684                                  Symbol poe Name (RefSeq) E3 ubiquitin-protein ligase UBR4   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism esim  Euwallacea similis Brite Enzymes [BR:esim01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      136409008 (poe) Ubiquitin system [BR:esim04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     136409008 (poe) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Other DBs NCBI-GeneID:  136409008 NCBI-ProteinID:  XP_066246370 LinkDB All DBs Position 5:5714546..5746631 Genome browser AA seq 5195 aa AA seqDB search MVEVMAANSGGVDWSLVLKPFLSPNYERSSTSELIELCSTIVKSESEVWRPNFYNTFTVL AADYISSSISKLSGSVSGGQLEIAIAACRVLLKSLLSALQSASSEQYQDSVAIERYLNAV KVMCTGTGLLSSTEVSNLVDIMKGEHLPQQTNVSPSGNDKESVSKQESSKNRPDLSVMIY EMLTLPIHDSSVSTSMSENLGDADPTTEIKRLFLIANTESLQALRAGDTLLDLCLNLPTI KKAKARIEEALAGRPYSIPSNHAEALAHRNSLPQTVSEITLAISAINLPVLEPLSAPKLD KLCNLAMAVLHCAVAQAAASGCLAAVNVASPKAQAASLKEEDLDSNAIKLVEEALSMYSY IGAKISTRAGTHAYQNYLLAGAWVLISGLQTIQAHLTQTTSGSSNDRPSTHLSRDSRERD SERSRPSPSKQTQQGRESMPSSSGSGGSPRSGLQKFQQCFGVLSVALATKALGLLSDLFE NLSLEMSGGSIGSLVTIEPAPLAILGQFSALQRVARVLSAAPLNHLLFYLSIVSYRKACS LKRLIPPEGDNFSQSDSTAYFEDMILYSDDNSTDEDDDSEPILGQWFEEILVPPEPQESK SPSTSENADTKSNNQGNNGRSVVPEKGEVDGYISLATSIFVFLNKHFLRSKSIFVQRYVK NGLTEQQMIILAAIIRDLDREWLKSELGGQYVEFSNALMKFTHNLITSNSLTPLQACLLN HLGVSPWNADVPHAWPLQVYPRTLSVLAQVLLLRPQNEKEASVISIWHRLVNTLIENVLN HPDAATESDIEDLNVEHAEVLLYLFHSLNLMQKKSVVLLMAGGVLRCSEIARSSLKESQL LNLSRLLLLFDYIMKHLYDVPAFLLEKIQRNLFELIYLNSDKEPAAPKPETAWESIEDAY RKLSNELHPSPTPRFYKLSNLEVNNQDSPKLDGLACKFILGNSDKLKYHLLLDALIEIMN VAHNINATSAAKMSVLGLCATQYCFTICWRLLHLLPPSIPYMEKLAQGEPLAPGPLLMHS LVWGPRAGHKNFNRWLKDCLVKQGMYNQNIDKLLKAVSDAVNNIEYDTAVAKKCILSLMP EPAEGVITKEEMPPLWHLILLDCLVAKVEVSLGEVSEPESSPVAISEPSCVHDLVPIVIR LARSILQYTRWSMFHMCVDHSENSDKIQLRDLELLDDVLAISSKESVLLATLQREITSFL PENVELGVNEWTYSSLYSGSPMDYSNDIIPSESYLLKIIDIHMSSLSKCVPFNLGYSLKR TFDNLATFIVHHAPRIENTDTKNKAIELLIAITTDVRTEFLHSVAIKALDKMIGDTEIDE RQKRVYISFLDHTYNLLMKYTSGAADQPEKRLVNEKILHSCLQFYEKIIEKSSGRQAFSS FFTGDKHLVNVLMSVSSPYMSQQYSTRVLHFFNKLFQAAEKSSTDPSLNYLCSSIGKLAE IESEKLQAWLRQIIIGPAESTSKSEVFTLKLKKQSSAGSANSKDVVITLGANEDKKSLVV ENSQLLQALTSYIVKQTSNVAEDVSITILKSLIPLGSHLLEPTLEGAGFSELMDIMTMLA DAGTGRGHSHLFPIAAEWVELCVKYVQNQEISDKIANSPDLLKNNVMLNAASCILDYLTD VILSITDQPPRSVSPQWEHESPLDLELDWQEETNDDDESGEDSDEDSLCSKLCTFTVTQK EFMNQHWYHCHTCRMLDGVGVCSICARVCHKGHDVSYAKYGNFFCDCGAKEDGSCQALVK RSPAANPDSSYQRKEEGSDQPVLPSSLRRQTSSPMPSDKILFEERRDHEKKKLEDSKEVL LNYLSSSSVTSSLLEFLQGLIPAIESTCNSNSPVGCHVRGVKALEQLHKAEKKYVHTDHL MMPTLGSQEGAFENVRMSYAGDQGQTIRQLLSAHIIRRVAMCCMTTTQGKRQHLAVSHEK GKITVLQLSALLKQADSASRKLTLTRLSSAPIPFTVLSMTSNLCNEEFLAVCGLKDCHVL SFNSTGAVTDHLVLHPQLETGNFIIKALWLPGSQTELALVTADFVKIFDLSKDATNPQYH FLVPSGKIRDCTFMYEDGVYHILLMSSPGHIYTEDLNDDSSTKFGSFYVTNTLEVSHVDV TDTNGHLGGGGVSIYYSHTLMLLFYSYAQGKNFISPITSKSNCLSLVFPINIPQPSAGNN GSNSKSNNTRAPNPQPLCQWTEIPNHPGIICCTMQSSNQPVVLMLKPDTVLIQEIKVVPA KSKIMDMVAIRHNSGSELRTTLILLCEDGSLKMFIANMEQTGFWMSSSIQATVPMGSSLK PKKKKPIKTGKTSSALVFPVDFFEHCTAMNDVEFGGNDLLQVYNVAQLKHRLNTTGLYIA CNKSPFQVEVTNNDATMVMCGMRILAGSQDLQKVPSYVEIFGRIISFNITKSRWYDVPFS REESLQADKKLTIVFGPCHGQDSELMTMVDSIKIYGKTKDSFGWPEDSDETAVSGAVHSN NTAASAASSEADHQPGSSQQLTKLERLAMDVFKSLDSSLYIYTSEEKFAKLKPAALKIAT QLLTLPTPPSIQVHSKALMLTLHPTKQQYHAYKDLALLYHVSINLTAMTDQKDSGITDLD AESYYRLVLIVRGIAVSRPQNLMKFADTHASIHDIVLVDPLETKDKETTLKDDKTKKKND HLLLQLVNVLWMLHRLNPDILALAPVVIPGLKYTEQVVHALVEIIHAFQSSESYGKVAIT LYLQLLLCQDPVIAFSAKQALGKVLKPRVKRRKVYMPSPTRCDSPSISKSSVLPSTSASV NQSEVAPQQPSVAPPPAVGAFDVGMIEAINMLENQPEGGVNALEALLGGDVGFHPLLDLP ADADETMVELAIALSLQDHEIGRSRTDQALFQNLQAQLRGAAQSGQGQAAAAQVHQEASN FSDTTASAAGSDDEGSTAATDGSTLRTSPAEQGGSAGSESGGSGVESITGEHNVSGRSSA YGDDTNVPRTTETSSGIASAQVAVEQSQRPSQGSDTLAQIQEDLESESESSTKLHGLRLQ LLEKLVEYLPKLKNADGVRTIPFFQVVSQLTSDLDGSCERDKACLNSLLATLSEELQFNG ENTQEICVRSKSGEVYLLLLKLISNILQRSKSVATSKSSSSNDPSNYVVRTSATFLHKAG IINFCLRISQSLLNDYWKNQVEEESSAGNLLKPHLTYPLPDMTPFFLKNHLKENSTDVFA NYEHLITEIVLRLPYQVQRLSEVSESTSDVFDAPWYRCLSEYMMTPLPPPSRRNARKLLL YICGSKEKYRQLRDLHALSTHSKGIKQCCTKGGYQTNSDLQPALNLSYDNLVELVEHLKA CLDIAVVRTGNWQRFCLHTEEILPFLLRVSFLLDEGVAPTTLQLLSSALVVNSNVPTKKP ESTNKTSRKDREKSDDSAVEALFEESNCVALVEQLNQQVSKEVLARFIKTFTLENNTTTV RWQAHGLVSAIYNNSKPMEQETLLELLWQLWPLLPAYGKKARQFVDFMGYSSLTYTEQKE GEKKIDEYVRKAVAVLKAQNSMLAHHPNANLYSHMSQFVKLDGYYLESEPCLVCNNPEVP FTSIKLSSIKVDSKFTTTTQIVKLLSSHIISKITVRIGDLKKTKMVRTINIYYNNRSVQA VVELKNKPALWHKAKKVTLQSGQTEVKIEFPLPIVACNLMIEYADFYENIQASSETLQCP RCSASVPANPGVCANCGENVFQCHKCRAINYDEKDPFLCHACGFCKYAKFDLTLQAKPCC AVEPIENDEDRKKTVSTINTLLEKADRIYKQLMANKSALESLVLRVTEHRSDDKKDETTT AANNNTTAQNPVSAVPISQVKVNKSIQMLAQQYCSECKTSFEELSKIIQKVLASRKELVN YERKHHDMDLSESTSVFEDLKITALPCVINKCYGCASAATENCLTMLRALALNKATRQTL CSYGLIQELVWSNLRKGNVRNQEEVRQLLCTVTRDNPDATEGLCNLLMTRITNCLNGNLN STDLGSTIRHEIALLASMLEEVDDCWELKLSCMLSLFIKACEDPKSPTVMESVILPCLKI LECLVKIQETPPLAASNKKAKEKSNSDKATTVPKLAPLQAPVEVRKFLSKVSEHSFSGWK SRALRPSDTTATTAAAKEAVRMQYLAEKYARKWRHRVKKLSGDSGTLALSSTSWVETVMF NPSSRQARSLACNIVEMMCNTYERKMKFITLLTCFLSKLSEAGEAAAEFLKLYQKLVQAT SWKQYLTVKGLPLVLANLMTQEIEQLHRLEATTLTSDLAQGYALYQLTGLLESFLEDAAI RRHYKSKLVGAVLNGYLSLRRLVVQRTRLIDETQDKLLALLEEMTTGTEEETKAFMSVCI KTVERYSLQDILTPVFIFERLCSIIYPEENDVGEFFLTLEKDPQQEDFLQGRMLGNPYSS NEVGLGPLMRDVKNKICQDCELVALLEDDNGMELLVNNKIMSLDLPVKDVYVKVWVQEGG DHDAMRVVYRMRGLLGDATEEFIETLDNKEQSTVDNEEVYKMANVLADCGGLKVMVTRLG AIQNARRAKPLLQVLLKLFTLSVKVNRCQEVLIEPELGAIEAFLRVLQLCLKGEPDSSQS VLIEQVLDIMETLMSKATTEPLDVFEALSQTFGGPEYVKALLSFTVHPSVKNNTAVLTHL TRVLAALVYGDEVKMGMVLHHFSDSVLFDRYDALHNMDNQQKFENQQQKMEMFCMLTNSI ERNAIGNTLKDYILKFDIVKNALKYIARHAPCVKPTLLRTDSDELKRFISKPALKYILRI LTGLAHSHENTQLELAKAETISIIHRLEQVSSDEHVGSLAENLLEALCTNPAVAKQIEEV REFTRSEKKRLAMAMREKQLGQLGMCTNDKGQVTAKSTILQQIEELGEESGLVCCICREG YKYQPTKVLGIYTFTKRCNVEKFEYAPRQTVGYSTVTHFNVVHIDCHMSAVRLARARDEW ESAALQNANTKCNGLLPLWGPQVPESAFASCLARHNTYLQESTNHRDIGHASTVHDLKLL LLRFAQVKTFHEDTGGGGPQSNMHLVPYLIHVGLYVINTTRVYFREYGSLTLYKGTDIKV DLAYQVEGPLYMATLALFLKSKREWEKERLEHLSRLIVIAHVRSFQPRRLDSGLGDKSIK DYYVYRPYLIFFGLIDAIYTYFFKDVEGEYDQWPTNLADYIRHNDEGLMKNSDKLLAFYT GDLLPCASFAEFCDVLDLYDVNPDTYITSVLDSVK NT seq 15588 nt NT seq  +upstreamnt  +downstreamnt atggttgaagtaatggcagctaatagtggtggagtggattggtcccttgttttaaaaccc tttttgtccccgaattacgaaaggtcaagcaccagcgaactcatagaactatgttccaca atagtgaagagcgagtccgaggtttggaggcccaatttctacaacacctttaccgtccta gccgcggactacattagcagtagcatatcaaaattgtctggttcagtgtctggtggtcaa cttgaaatcgcgattgcggcatgtagagtcttattaaaatctctactcagcgccctgcaa agcgccagtagtgaacagtatcaagacagcgtcgcaattgaacgctatttaaatgcggtc aaagtaatgtgcactggcactggcctgcttagctccacagaagtgtccaatctagtcgac atcatgaagggagaacatctccctcagcagaccaatgtgtcacctagcggaaatgataaa gaatcggttagcaaacaggaatcatcaaaaaaccgtccggatttgtcggtgatgatatat gaaatgttaactttgcctatccatgactcttcagtcagtacgtctatgtccgagaattta ggagatgcagatcctactacagaaatcaaaagattatttttgatagcaaacactgagagt ctccaggctcttagagctggagatacacttcttgatttatgcctaaatttacccacaatc aagaaagccaaagctagaattgaagaggccttggcaggcaggccctacagtatcccttct aatcacgccgaagcattggcacatagaaatagtctccctcaaacagtgtcagagataact cttgctatatcggcgataaacttgccggtattagagccactcagtgccccaaaattagac aaactgtgcaacttggcaatggcggttttgcactgtgcagtagcacaggctgctgcaagt ggatgtttagctgctgttaatgttgcttctcctaaggctcaagctgccagtctcaaagaa gaagatttggattctaatgcaataaaattagttgaagaagctttgagtatgtactcatat attggagctaagatttctactagggcaggaacacatgcctatcaaaactatcttcttgct ggcgcctgggtacttatatcaggactgcagacaatccaggctcatttaacacaaaccacc agtgggagttccaatgacagaccttctacgcacctttccagggactcaagagagagagat tcagaacggtcaaggcccagtccaagcaaacaaacccaacagggtcgtgaatctatgcca agcagttccggcagcggcggatcgccccgatcgggtcttcaaaagttccagcaatgtttt ggtgtgttaagtgttgccttggccaccaaggcattgggactgttgtcggatctgttcgaa aatcttagtctggaaatgtctggagggtccattgggagccttgtaacgattgagcctgcg cctctcgccattcttggtcaattctcagcccttcagcgtgtcgcgcgtgtgctaagcgca gcgcctctcaaccatctgctgttttacttgtccattgtcagttaccgcaaggcttgttct ctgaaacgactcatcccccccgaaggggataatttcagccaatccgattccacggcctat ttcgaagatatgatcctttatagcgacgacaattccaccgatgaagacgatgatagtgag ccaatcttaggtcaatggttcgaagagattttggttcccccagaaccacaagaatcgaaa tccccttcaacatctgaaaacgccgatacgaagtcgaataatcaaggcaacaatggacgt tcagtggttccggagaagggagaggtcgacggttacatttctctagctaccagcatcttc gtatttctaaacaaacatttccttcgttcaaagtccattttcgtgcagcgctacgttaaa aatggcctcaccgagcaacagatgataattttagcggccattattcgggatttagatcga gaatggctcaaatctgaattgggggggcaatatgtagagttctccaacgcactcatgaag tttacccacaatttgattactagcaatagtttgacgccacttcaagcatgtcttttgaat catttaggcgtgtcaccgtggaacgcggatgtgcctcatgcttggccattgcaagtttat cccaggacgttatcggttttagcgcaggttctattgctgagacctcaaaatgaaaaggaa gcatcagtgattagcatctggcaccgattggtaaatacgttaattgagaatgttctaaat caccctgacgccgcaactgaaagtgatattgaagacttgaatgtagagcacgcagaggtc ctcctgtatctcttccactccttgaatttgatgcagaaaaagtcggtcgttctactaatg gccggcggcgtgctcagatgctcagaaatagcccggagcagccttaaagaatcgcaatta ctcaacttatcccgacttttattgttgttcgattacatcatgaagcacctttatgacgtg cccgcatttctgctcgaaaagatccaaaggaatttgtttgagcttatttacttaaactct gacaaagagcctgccgcacccaagcccgaaacagcttgggagagcatcgaggacgcttat cggaaattgtcaaacgaattgcacccttctcccacaccccgcttctacaaactgtcaaat ttagaggtgaacaaccaagactctccgaaactggacggtttagcctgcaaattcatcctg ggaaactcggacaaactcaagtatcacctcctcttagatgcgctgattgaaatcatgaac gtggcgcataatataaatgccactagtgccgccaaaatgtccgtgttgggtttgtgcgcc acacaatattgttttaccatttgttggaggttgttgcatcttctgccgccgtccataccg tatatggaaaaattggctcaaggagaaccgctggcgcccggccctctcttgatgcattct ttagtgtggggacctcgagccgggcataagaattttaatcgctggctcaaggattgtctc gttaaacaggggatgtacaatcagaatatcgataaactattaaaagccgtgtccgatgcc gtaaacaacatcgaatatgacacagcagtggctaaaaagtgcattttgagtctcatgcct gagccagcagagggcgtcataactaaagaggaaatgccgcccctttggcacctcatttta ttagattgtttggtggctaaagtagaggtgtctttgggtgaagtctcggaaccggaaagt tcaccagtggccatttcggaaccttcttgtgtccacgatttggttcccatagttatacgt ttggcacgatcaattctacaatatacccggtggtctatgttccacatgtgcgttgaccac agcgaaaattccgacaagattcaactgagggatctggaactgttggacgatgttttggca atttcctcaaaagagagtgtcttattagcaacgctacaacgtgagattacgtcatttttg cctgaaaatgtggaattgggagtgaatgaatggacatattcttccttatattcaggatct ccgatggattattccaacgacattatcccctctgagagctacctcctgaaaataatagac atccacatgtcttctctatcgaaatgtgtgccctttaacttgggttactccttgaagcgt acattcgataatttggcaacgttcatagtgcatcacgccccccgaatcgagaatacagat acaaaaaataaagctatagagttgcttattgccattacaacagatgtgagaactgagttc ttgcacagtgtggcaattaaggctttggacaaaatgatcggagataccgagattgatgaa agacagaaaagggtttacattagttttttggatcacacttacaatttgttgatgaaatat accagcggagctgcggatcagcccgaaaaacgcctggtcaacgagaagattttgcatagc tgtctgcaattttatgagaaaattatagagaagagttcaggaagacaagcattctccagc ttctttactggagataaacacctagtgaatgttttaatgtcggtctcaagtccatacatg tctcaacaatacagcactcgcgttttacatttcttcaataagttattccaagcagcagaa aagagttcgaccgatccgagtttgaattatctctgctccagcatcggaaaacttgccgaa attgaaagtgaaaagttgcaggcgtggttgaggcaaattatcatcggacccgctgaatcc acatctaagagcgaagtttttactctgaaattaaagaagcagtctagtgctggtagcgcg aattcgaaagatgtagtgattacgttgggagccaatgaagataaaaaatcgctagttgta gagaatagtcagttgctgcaggctttaactagctatatcgtgaagcagacaagtaacgtc gccgaagacgtttcgataacaattctaaaatcccttatacccttgggaagtcacctattg gagcccacattggaaggagccggttttagcgaattaatggacatcatgaccatgttagca gatgccggaacgggtagaggccatagccatttatttcccattgccgccgagtgggtggag ctgtgcgtgaaatacgtgcaaaatcaggaaataagcgacaaaatcgccaattctccggat ttgttaaaaaacaatgttatgttgaatgctgcctcgtgcatcctggattatttgactgat gttattttgtctattacggatcaaccaccaagatctgtgtctcctcaatgggaacatgaa agtcccttggatttggaactagattggcaggaggaaactaatgatgatgatgagagcgga gaagattcagacgaggattctctgtgcagtaaattgtgtactttcacagttactcaaaag gaatttatgaatcagcattggtaccattgccatacatgtcggatgctagatggcgtaggc gtctgttcaatttgtgcccgcgtctgccacaaaggtcacgacgttagctacgctaaatac ggcaatttcttctgcgattgcggagcgaaggaagatggctcgtgtcaggcgctggttaag cgtagtccggccgccaatcccgattcatcctatcaaaggaaagaagaggggtcagatcag ccagttttgcccagttctttgagaagacaaacgagttctccgatgccttccgataaaatc ttgtttgaggagaggcgagatcacgaaaaaaagaaactagaggactccaaggaggtgcta ttgaactatctgagttcaagttctgtaacatcttctttattggaatttctgcaaggcctg atccctgccatagaatcgacatgcaactccaatagtccggtaggctgtcacgtgcgcggc gttaaggctctagaacaattgcacaaagccgaaaagaaatatgtgcatactgaccatttg atgatgcctactttgggttcacaagagggagcgtttgaaaacgttagaatgtcatatgca ggtgatcaaggtcaaactatcaggcagttgttgtccgcccatattataaggcgggtggcc atgtgttgcatgacgactacacaaggaaagcgacagcatctggcagtctcacacgaaaag ggcaaaatcaccgtcttgcaattatcggccctcctcaagcaagctgattcggcgagccgg aaattaaccttaacccgccttagttccgcccccattccgtttacagtgctctcaatgacg tcaaacctctgcaacgaagaatttctagccgtgtgtggtttgaaggattgtcacgtgttg tctttcaactccactggagcggtcaccgatcacttagtcctgcatccgcaattagagacc ggcaattttatcatcaaagctttatggttgcccggatctcaaactgagctcgctttagtc acggccgactttgtaaagatcttcgatcttagcaaagatgctacgaatcctcagtaccat tttcttgttcccagcggtaaaatcagggactgtacttttatgtacgaagacggtgtttat catattctcctcatgtcttcgcctgggcacatttacaccgaagatctcaacgacgacagc tctaccaaatttggtagcttttacgtcaccaataccttggaagtttctcatgtggatgtc actgatacgaatggtcatttaggcggcgggggagtctcgatatattactcacatacatta atgttgctcttctacagttacgcccaagggaaaaattttatttcgcccattacctcgaag agtaattgtctttctttggttttccccattaatattccccaaccctcggcgggcaataac ggctccaattccaagagtaacaacacaagagcgccaaatccccaaccactgtgccagtgg actgaaatccccaaccatcccggaataatctgctgtacaatgcagtcgagtaaccagccg gtcgtattgatgcttaaacccgatactgtcctcattcaagaaattaaggtagttccagcc aagtcaaagataatggacatggtcgcaattagacataattcaggcagtgaactgaggacc accttgattttgctgtgcgaggacggaagcttgaaaatgtttatcgccaatatggaacaa actggtttctggatgtccagcagtattcaagccacagtcccaatgggctcgtcactcaaa ccgaagaagaagaaaccaataaagacgggcaaaacctcaagcgccctagttttcccggtg gatttctttgagcattgcacagcaatgaacgatgtcgagttcggtgggaatgatttgctg caagtttacaatgtggcccaactaaaacacagattaaacaccactggcctttatatcgcc tgcaacaaatccccattccaagtggaagtgaccaataatgacgcaactatggtaatgtgc ggaatgaggattctggctggaagtcaagacctacagaaagttccatcttatgttgaaata tttggacgaataatttcatttaacatcacgaaaagtcgttggtatgacgtcccgttttca cgggaggaaagtctgcaggccgataagaagctgactattgttttcgggccttgtcatggt caggattcggagcttatgactatggtggacagtattaaaatatacgggaaaaccaaggat tcctttggatggcccgaagacagcgatgaaacagcagtttctggtgctgttcattcaaat aatactgcggcttctgctgccagcagcgaggcggatcatcaacccggttcttcgcagcag ctcaccaaactggagcggctggccatggacgtctttaaaagccttgattcctccttgtat atttacacatctgaagagaaatttgcgaaactcaagcctgcagctttgaaaatagccact caactcttgaccctcccaacaccgccctcaattcaagtgcactccaaagcgctaatgttg actttgcatcccacgaaacagcagtatcacgcctacaaggatctggcgctgttgtatcat gtttcgatcaatttgactgcgatgactgaccagaaagattcgggcattaccgatttggat gccgaaagctactatcgcctcgttctaatagtaagaggaattgcggtttcccgtcctcaa aacctcatgaaatttgccgatactcatgcctcaatccacgacatagtcctagtagacccc cttgaaaccaaagacaaagaaaccactttaaaagatgataaaactaaaaagaaaaatgat catttgctgctgcagcttgtaaacgtactttggatgctgcatcgcttaaaccctgatatt cttgctttagcaccagtagtcattcctggtttgaagtatactgagcaagtagttcatgct cttgtggaaatcatccatgccttccaaagctctgagtcctacgggaaagttgcgattacc ctatatttacaattactactctgtcaagacccagtgattgcgtttagcgctaaacaagcc cttggcaaggttttgaagcctcgcgttaaacgccgaaaagtctacatgccttctcccact cgttgtgacagcccctccatttcaaaatcttcagttcttccttctacatcagcctcagtc aatcaaagtgaagtagcgccacagcaaccgagcgtggccccgcctccagcggtcggagcc ttcgacgtaggcatgattgaggctattaatatgctggagaatcagcctgagggcggagtt aatgcgctagaagcgctcttaggaggggatgtgggattccacccacttttggatctgcct gcagacgctgatgagaccatggtggaactggccatcgctttaagcttacaggaccatgaa ataggcagaagccgcaccgatcaggccttgttccagaatttacaagcgcaattgagagga gctgcacaaagtgggcagggtcaagctgccgccgcgcaggtgcaccaagaggcctcaaat ttcagcgacaccacagcttcagctgcgggttcggatgatgaaggttctactgctgcgact gacgggtcaactttgcgcacctcccctgcggaacaaggcggcagcgcagggtctgaaagc ggaggcagtggcgtcgaaagtattactggagaacacaacgtttcaggcagatcttctgca tatggagacgacaccaatgttccaagaacaacagaaactagctcgggcattgcttcagcg caagtagcagtggagcaatcacagcgcccttctcaaggaagcgatactttggctcaaatc caagaagatctggaaagcgagagtgagagcagcaccaaattacatggtctgagattacaa cttctggaaaagcttgtggagtatttaccaaagctcaaaaatgcggacggagtccgcact attcctttcttccaagttgtttctcaattaactagcgacttagatggatcttgcgaaaga gacaaggcctgtctcaattccttgttagcaactttaagcgaagaacttcagtttaatgga gaaaatacccaggagatttgcgtgagatccaaatcgggtgaagtgtatttgttgctcttg aaactgatttctaatatactgcagcgcagcaagtctgtagccacatcgaaatcgagcagt tccaacgacccttctaactacgttgtacgcacttccgcaacttttttgcataaagcagga ataatcaacttttgtttgcgaatcagtcaatcgctgttgaatgattactggaagaatcag gtcgaagaagagagctctgcggggaatttgctgaagcctcatctcacttatccactgccc gacatgacaccgttctttttgaagaatcacctaaaggagaattctaccgatgtttttgcc aactatgaacatttaatcacagaaatagttctaagattgccgtaccaagtgcaacgtttg tcagaagtgagcgaatcgaccagtgacgtttttgatgcaccctggtacagatgcctcagt gagtatatgatgactcccctacctccgccctcgcgaagaaacgcccgaaaattgctgttg tatatctgcggcagcaaggagaaatatagacagttgagggatttgcacgcgcttagcacg cattctaaaggtatcaaacagtgctgcaccaagggcggttatcaaacgaactccgaccta caacccgccttaaatttatcttacgataatctagtggaactcgtggagcacttaaaagct tgcttagacattgcagtagtaagaacgggaaactggcaacgtttttgtcttcacaccgag gaaattttgcctttcttactacgagtcagcttcctgctcgacgagggcgtagcccccacc accttgcagctgttgtctagtgctctagtggttaattctaatgtaccgactaaaaaacct gaatctaccaataaaacaagtcgcaaggaccgagagaaatctgacgattcagcagttgaa gcgctctttgaagaatccaactgcgtagcattagtggagcaactgaatcagcaggtttcc aaagaggttttggcacgatttattaagacttttacgttggaaaacaacactaccacggtg cgatggcaggctcacggcttagtgtcagcaatttataacaattcgaaaccgatggaacaa gagactctgctggagttgttgtggcagttgtggccacttttacctgcatacgggaagaag gcgaggcaattcgtagattttatgggatactcttcgttgacttacactgaacaaaaagag ggcgaaaagaagatcgacgagtacgttcgaaaggcggtggccgtcctaaaggctcaaaac tcgatgttggctcaccaccccaacgctaatctttactcccacatgtcgcaattcgtcaaa ttggacggttactatttggagtccgagccgtgtttggtttgcaataaccctgaggttccg tttacaagtatcaaactgtcgtctattaaggtggactctaaattcaccaccaccactcaa atcgttaagcttttaagcagtcatattatcagcaaaatcactgtgagaattggggattta aagaagaccaagatggtcaggactattaacatttattacaacaataggagtgtgcaagct gtggtggaattgaagaacaaaccggcattgtggcataaagccaaaaaagtgacccttcaa tctggtcaaacggaggttaaaattgagtttcccttacccatcgtcgcctgtaatttgatg atcgaatatgcagacttttacgaaaatattcaggctagcagtgaaaccttgcagtgtccc agatgcagcgcttccgtgcccgccaatcctggagtatgcgccaattgcggggaaaacgtg ttccagtgtcacaaatgcagagccatcaactacgatgagaaagacccatttttgtgccat gcttgcggtttctgcaaatacgccaaattcgacttaacgttgcaggctaagccctgctgc gctgttgaacccatagagaacgacgaggatcgaaaaaaaaccgtttccaccatcaacact ctcctggaaaaagcagaccgcatttacaagcagttgatggccaacaaatctgccttggaa tctttggtgttacgtgtaactgaacacagatcggacgacaagaaggacgaaaccaccacc gccgcaaacaacaacaccaccgcacagaacccggtcagtgctgtgcccatctctcaagtt aaagtcaacaaatctatccagatgttagcacagcagtactgtagcgaatgcaagacaagc tttgaggaattgagtaaaattattcaaaaggtattggcgtctagaaaagaacttgtaaat tatgaaagaaaacatcatgacatggatctttccgagagtacttctgtgtttgaagattta aagataaccgcccttccctgtgtcataaacaaatgctacggttgtgcatcagcggccaca gagaattgtctcactatgttgagagctctcgctctcaacaaggcaacgaggcaaactctg tgctcctatggtctcattcaggaattggtatggagtaatttgagaaaaggaaatgtgcgt aaccaagaggaggttagacagctgctgtgtactgtaaccagggataatcccgatgcgact gaggggctttgtaatctgttgatgacgcgcattacgaattgtctcaatgggaatttgaac agtactgatttgggctcgaccatccgccacgagattgcacttttagcttctatgttggaa gaggtggatgattgttgggaactgaagttgagttgcatgctatcgctgtttataaaagcg tgcgaggacccaaagagtcccactgtgatggaaagcgtcatattaccatgtctgaaaatc ctggaatgtttggtaaaaatccaggaaactcccccactcgccgccagcaacaagaaagca aaggagaaatccaattctgacaaagcaacaactgtgcccaaattggcaccattgcaggcg ccagtggaggtgcggaagtttttgagcaaagtttcggaacactcgttttctgggtggaag tcacgcgccttacgtccatctgacaccactgcaacgacagcggctgccaaagaggctgtg cgcatgcaatacttggccgaaaaatatgcgcgcaagtggcgccaccgcgtaaagaaacta agtggcgacagcggaacactggcgctcagttccacctcgtgggtagagacagtgatgttt aatcctagctcgcggcaagcgcgaagtctggcttgcaacatagtcgaaatgatgtgtaac acttacgagcgcaagatgaagttcatcacgttgctcacttgcttcctgtcaaaactgtct gaggcaggcgaagctgccgccgaatttttgaaactctaccagaagcttgttcaggccaca tcttggaagcaatacttaaccgttaagggtctaccgctcgttttggcgaacttgatgaca caagaaatagagcaattgcatcgtctagaagccactacgctaacatcagacttggcccag ggttacgccttatatcagctaaccgggctgctggaaagcttcttggaggacgccgccatc aggcgacattacaaatctaaactagtcggagccgttttgaacggttatttgtccctcaga cgtttagtggtgcaaaggaccagattaattgatgaaacacaggataaactgctcgcattg ctcgaagaaatgacaacaggcaccgaagaagagactaaagcgttcatgtcagtatgcatt aaaacagtagaacggtacagtttacaagacatcctcacacccgttttcatattcgaaagg ctgtgctcaataatttaccccgaggaaaacgacgtaggagagtttttcctgactttagaa aaagatccccaacaggaagattttctgcaagggcgcatgttgggcaatccctattcgagt aacgaggtgggtttgggacccctaatgcgcgatgtgaaaaacaaaatctgccaagattgt gaattggtcgctttactcgaagacgataatggtatggaactgttggtcaacaacaaaatt atgagtctggacttgccggtcaaggatgtatatgtgaaggtgtgggtgcaggagggaggc gaccatgacgccatgcgagttgtgtacaggatgaggggtctcctaggggatgccaccgag gaattcattgaaaccttggacaataaagagcagagcaccgtcgataacgaagaagtttac aaaatggctaacgtgttggctgactgcggaggtctgaaagttatggtaacacgattgggg gcaattcagaacgcccgtagagctaaaccacttctgcaggtccttcttaaactgttcacg ctcagcgttaaagtaaatagatgccaagaggtgctcattgagccagaattgggggccatt gaagcctttttgagggttttgcagttgtgtttgaaaggcgaacctgattctagtcagtca gtcctaatcgagcaggtgcttgatataatggaaactttaatgtctaaagccactacagag cctcttgatgtctttgaggcgttatctcaaacttttggaggacctgagtatgtcaaggct ttgctttcgttcacggtccatccttcagtgaagaacaacaccgcagtcttaactcactta acgagagttttagctgctttagtttatggcgatgaagtgaaaatggggatggtactgcat catttcagcgacagtgttttgtttgatagatatgatgctctgcataacatggataatcag cagaaattcgaaaatcagcagcagaaaatggaaatgttttgtatgctcactaacagtatt gagcgcaatgcaatcggcaacactttgaaagactacattttaaagttcgatatcgtgaaa aacgccttgaagtatattgcgaggcatgctccatgtgtcaaaccaactcttctgcgaacc gatagtgatgagttgaaacgcttcatctcgaaacccgcattaaaatacattctcagaatt ctcacaggtttggcgcacagccatgaaaacactcaattggagttggccaaggcagaaacc atttctattatccatcggttggagcaggtttcgtcagacgagcacgtggggtctttggca gagaatttgttagaggctctgtgcaccaaccctgcggttgccaagcagatcgaagaggtg cgagaattcacgagatctgaaaagaagcgtttggcaatggcgatgagagagaaacagttg gggcagttaggcatgtgcacaaacgataaaggacaggtgacagcaaaatcaacaatcctc caacaaattgaggaattaggagaggagtcgggtttagtctgctgcatctgtcgtgagggg tataaatatcaacctaccaaagtactcggtatttacacttttaccaaacgatgtaacgtt gagaagtttgaatatgcgcctcgtcaaactgtcggctattcgacagtgactcacttcaac gtggttcacatagactgtcacatgtcagcggtacgactcgctagggcgcgtgacgaatgg gagtctgctgctttacaaaatgctaataccaaatgcaatggactgttacctttatggggc cctcaggtgcctgaatcggccttcgctagctgcttggcaaggcataacacttatttacag gaaagcaccaaccatagggatatcggtcatgcgtcaacagttcatgatttaaagctgttg ttgctgcgattcgcacaggtcaagacgttccacgaggacaccggcggcggcggcccgcaa agtaacatgcatttggtgccttatttaattcacgtgggactatatgtcatcaatacaaca agagtatactttagggaatatggctctctcaccctatacaaaggaaccgatattaaagta gatttggcctatcaggtggaaggtccattgtatatggccaccttggctttattccttaaa agcaaacgcgagtgggagaaagaacgcctggagcacttgtctaggcttatagtgatagcc catgtgaggtcgtttcagcccagacgactcgattcgggccttggtgataaatcgatcaaa gattactacgtttacaggccgtacctgatatttttcggcctgattgacgctatttataca tatttctttaaggatgtggagggtgagtacgatcaatggccgacaaatttggcggactac attcgccacaatgatgagggacttatgaaaaattctgataaattgctggctttctacacg ggcgatctccttccctgtgcttctttcgctgagttttgcgatgtgcttgatctatacgat gtgaacccagacacctacattacttcagttttagatagtgtaaagtag

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