KEGG   Escherichia coli O104 H4 2011C-3493 (EAEC): O3K_02225
Entry
O3K_02225         CDS       T02257                                 
Symbol
cysG
Name
(GenBank) siroheme synthase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
esl  Escherichia coli O104:H4 2011C-3493 (EAEC)
Pathway
esl00860  Porphyrin metabolism
esl01100  Metabolic pathways
esl01110  Biosynthesis of secondary metabolites
esl01120  Microbial metabolism in diverse environments
esl01240  Biosynthesis of cofactors
Module
esl_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:esl00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    O3K_02225 (cysG)
Enzymes [BR:esl01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     O3K_02225 (cysG)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     O3K_02225 (cysG)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     O3K_02225 (cysG)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M Col-Pyo_DNase Radical_SAM
Other DBs
NCBI-ProteinID: AFS72374
UniProt: A0A0E0XUR4
LinkDB
Position
complement(469448..470821)
AA seq 457 aa
MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFTAWADAGMLTL
VEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNVVDAPKAASFIMPSIIDRS
PLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQLRGRVKQQFATMGERRRFWE
KLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQ
QADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLK
GGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLITGHL
KTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEHGMPGEMPVAIVENGTAVTQRVID
GTLTQLGELAQQMNSPSLIIIGRVVGLRDKLNWFSNH
NT seq 1374 nt   +upstreamnt  +downstreamnt
gtggatcatttgcctatattttgccaattacgcgatcgcgactgtctgattgtcggcggt
ggtgatgtcgcggaacgcaaagcaaggttgctgttagacgcaggcgctcgcttaacggtg
aatgcattagcgtttattccacagttcaccgcatgggcagatgcaggcatgttaaccctc
gtcgaagggccatttgatgaaagccttctcgacacctgctggctggcgattgcagcgacg
gatgatgacgcgcttaaccagcgcgtcagcgaagccgctgaagctcgtcgcatcttctgt
aacgtggtcgatgcgccgaaagctgccagcttcattatgccgtcgattattgaccgctca
ccgctgatggtggcggtttcctctggcggtacttctccggttctggcgcgcctgttgcgc
gaaaaactcgaatcactgctgccgctgcatctgggccaggtagcgaaatacgccgggcag
ttacgcggtcgggtaaaacaacagttcgccacgatgggtgaacgccgccgcttctgggaa
aaactgttcgttaacgaccgtctggcgcagtcgctggcgaacaacgatcagaaagccatt
actgaaaccaccgaacagttaatcaacgaaccgctcgaccatcgcggtgaagtggtgctg
gttggtgcaggtccgggcgatgccgggctgctgacactgaaaggtctgcaacaaattcag
caggcagatgtggtggtctacgaccgtctggtttctgacgatattatgaatctggtacgc
cgcgatgcggatcgtgttttcgtcggcaaacgcgcgggataccactgtgtaccgcaggaa
gagattaaccagatcctgctgcgggaagcgcaaaaaggcaaacgcgtggtgcggctgaaa
ggtggcgatccgtttatttttggccgtggtggcgaagagctggaaacactgtgcaacgcg
ggtattccgttctcggtggttccgggtattaccgcagcttctggttgctctgcctattcg
ggtattccactcacgcatcgcgattatgcccagagcgtacgcttaattaccggacactta
aaaaccggtggcgagctggactgggaaaacctggcggcagaaaaacagacgctggtgttc
tatatggggttgaatcaggccgcgactattcagcaaaagctgattgaacacggtatgcct
ggcgaaatgccggtggcaattgtcgaaaatggaacggcagtcacgcagcgcgtgattgac
ggtacgctcacgcaactcggtgaacttgctcagcaaatgaacagtccatcgctaattatt
attggtcgggttgttggcctgcgcgataaactgaactggttctccaaccattaa

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