Escherichia coli O104 H4 2009EL-2071 (EAEC): O3O_19020
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Entry
O3O_19020 CDS
T02256
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
eso
Escherichia coli O104:H4 2009EL-2071 (EAEC)
Pathway
eso00230
Purine metabolism
eso01100
Metabolic pathways
eso01110
Biosynthesis of secondary metabolites
Module
eso_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
eso00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
O3O_19020
Enzymes [BR:
eso01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
O3O_19020
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AFS87535
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Position
1357607..1361491
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AA seq
1294 aa
AA seq
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MEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLNAPLNDDEHAQLERLLKY
GPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTLTN
EQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGLA
LAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWVIDGEQQPKSLFKMI
KNTFETTPDYVLSAYKDNAAVMEGSEVGRYFADHETGRYDFHQEPAHILMKVETHNHPTA
ISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIVT
ALDIMTEGALGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNIR
ADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERRC
QEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPLE
IWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDLP
LDVLLGKTPKMTRDVQTLKAKGDALAREGITIADAVKRVLHLPTVAEKTFLVTIGDRSVT
GMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEALT
NIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSM
KTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGAT
ALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFAG
HCGIDADIATLGDDRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVGQAVSG
DRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVKL
SFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLTGRTG
LEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQMM
SNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRV
EVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITSITTESGRVTIMMPHP
ERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG
NT seq
3885 nt
NT seq
+upstream
nt +downstream
nt
atggaaattctgcgtggttcgcctgcactgtcggcattccgaatcaacaaactgctggca
cgttttcaggctgccaggctcccggttcacaatatttacgccgagtatgtccattttgct
gacctcaatgcgccgttaaacgatgatgagcacgcacaacttgaacgcctgctgaaatat
ggcccggcactcgccagccacgccccgcaaggcaaactcctgctggtgaccccgcgtcct
ggcaccatctctccctggtcttcgaaagcgaccgatattgcccataactgcgggctacaa
caggtaaaccgccttgagcgcggcgttgcttactatatagaagccggtacgctgaccaat
gaacaatggcagcaggttaccgctgaactgcacgaccgcatgatggaaacggtctttttt
gctttagatgatgcagagcagctgtttgcacaccatcaaccgactccggtcaccagcgtt
gatttgctggggcagggccgtcaggcgctaatcgacgctaacctgcgtcttggcctggca
ctggcggaagatgaaattgactatctgcaggatgctttcacaaagcttggtcgtaacccg
aacgacatcgagctgtatatgttcgcccaggcgaactccgagcactgccgccacaagatt
tttaacgccgattgggttatcgacggtgagcaacagccgaaatcgctgtttaagatgatc
aaaaacaccttcgaaaccacgccagattacgttctctctgcttataaagataacgccgcc
gtaatggaaggttctgaagtgggccgctactttgctgaccacgaaacgggccgctacgat
ttccatcaggaaccggcgcatattctgatgaaagtcgaaactcacaaccacccgacggcg
atttctccgtggccgggcgcggcgaccggttccggcggtgaaatccgcgatgaaggtgcc
accgggcgcggcgcgaagccgaaagcgggtttggttggtttctccgtttccaacctgcga
attcctggcttcgaacagccgtgggaagaagatttcggtaagcctgagcgcattgtcacc
gcgctggacatcatgaccgaaggcgcgctgggcggcgcggcgtttaacaacgaatttggt
cgtccggcactgaatggctacttccgtacttatgaagaaaaagtgaacagccacaacggc
gaagagctgcgcggttatcacaaaccgatcatgctggcgggcgggatcggcaacattcgt
gccgatcacgtacaaaaaggcgagatcaacgttggtgcgaagctggtcgttctcggcggc
ccggcaatgaacatcggtcttggcggcggcgcggcgtcttccatggcgtctggtcagtct
gatgccgacctcgactttgcttccgtccagcgcgacaacccggagatggagcgtcgctgc
caggaagtgatcgaccgttgctggcagcttggtgatgccaacccaattctgtttatccac
gacgtcggcgcaggcggtctttctaacgcgatgccggaactggtgagcgacggcgggcgc
ggcggtaaatttgaactgcgcgatattctaagcgacgaaccgggcatgagcccgctggaa
atctggtgtaacgaatcccaggaacgctacgtgctggcggttgctgccgatcaattaccg
ctgtttgacgaactgtgtaagcgtgagcgcgcaccctacgcggtgattggtgaagcgacc
gaagaactgcatctttctctgcacgatcgtcattttgataatcagccgatcgatctgccg
ctggacgtcctgcttggtaaaacgccgaagatgacccgcgatgtacaaacgctgaaagcg
aaaggcgacgcgctggcccgtgaagggatcaccattgcagacgcggtgaaacgcgtactg
catctgccgaccgtggcggagaaaactttcctggtgaccatcggtgaccgcagcgtaact
ggcatggtagcgcgcgatcagatggtgggtccgtggcaggtgccggtcgctaactgcgcg
gtcactaccgccagcctcgacagctactacggtgaagcgatggcgattggcgagcgtgcg
ccggttgcgctgctggatttcgccgcctctgcccgtctggcggtcggtgaagcgttaacc
aatattgccgcaacacagattggcgatatcaaacgcattaaactttccgccaactggatg
gcggcggcaggccaccctggtgaagatgcgggcctgtatgaagccgttaaagccgtgggc
gaagagctttgtccggcgctgggcctgacgatcccggtgggtaaagactctatgtcgatg
aaaacccgctggcaggaaggtaacgaagagcgcgaaatgacgtcgccgctgtcgctggtg
atttctgcatttgcccgcgtggaagatgtacgtcacaccatcacgccgcagctttctacc
gaagataacgcactgctgctgattgatttgggcaaaggcaataacgcgctgggcgcaacg
gcgctggcgcaggtttatcgtcagcttggcgacaaaccggcagatgtacgcgacgtcgcg
caactgaaaggcttctatgacgcgattcaggcgctggttgcacagcgtaagctgctggcg
tatcacgaccgctctgatggcggtctgctggtaacgctggcggaaatggcctttgctggt
cattgtggcattgacgcggatatcgccactctgggtgacgatcgcctggcggcgttgttt
aacgaagaactgggtgcggtgattcaggttcgtgccgctgaccgtgaagcggtcgagtcc
gtactggcacagcatgggcttgctgattgtgtccattatgttgggcaggcggtttccggt
gaccgttttgtgattaccgccaacgggcagactgtattcagcgaaagccgcactacgttg
cgtgtttggtgggcagaaactacctggcagatgcagcgcctgcgtgacaacccggagtgt
gccgatcaggagcatcaggcgaaatctaacgatgccgatcctggcctgaatgtaaaactg
tcgttcgatatcaacgaagatgtggcagcaccgtatattgccactggcgcacgtccgaaa
gttgctgtgctgcgtgagcagggcgtgaactcgcatgttgaaatggcggcagctttccac
cgtgcaggctttgatgctatcgacgtgcatatgagtgacctgctgaccggacgcacgggc
ctggaagatttccacgccctggtcgcgtgcggtggtttctcctacggtgatgtgctgggt
gccggtgaaggttgggcgaagtcaatcctgttcaatgaccgtgtacgcgatgagtttgca
accttcttccaccgtccgcaaacgctggcgctgggggtatgtaacggttgccagatgatg
tctaatctgcgtgaactgatcccaggtagtgagttgtggccacgttttgtgcgcaatacc
tccgatcgctttgaagcgcgtttcagcctggttgaagtgacccaaagcccgtcgctgctg
ttgcaggggatggtgggctcgcaaatgccgattgctgtctctcatggtgaagggcgcgtg
gaagtgcgtgatgcggcgcatctggcggcactggaaagcaaagggctggtggcactgcgc
tatgtcgataacttcggcaaagtcactgaaacctacccggctaacccgaacggttcaccg
aacggtattacgtcgattacgactgaaagtggtcgagtcaccattatgatgccgcacccg
gaacgtgttttccgtactgtcagcaactcctggcatccggaaaactggggcgaggatggc
ccatggatgcgcattttccgcaatgcgcgtaagcagttggggtaa
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