Etheostoma spectabile (orangethroat darter): 116671269
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Entry
116671269 CDS
T08457
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
esp
Etheostoma spectabile (orangethroat darter)
Pathway
esp04010
MAPK signaling pathway
esp04012
ErbB signaling pathway
esp04020
Calcium signaling pathway
esp04510
Focal adhesion
esp04520
Adherens junction
esp04530
Tight junction
Brite
KEGG Orthology (KO) [BR:
esp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
116671269 (erbb2)
04012 ErbB signaling pathway
116671269 (erbb2)
04020 Calcium signaling pathway
116671269 (erbb2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
116671269 (erbb2)
04520 Adherens junction
116671269 (erbb2)
04530 Tight junction
116671269 (erbb2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
esp01001
]
116671269 (erbb2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
esp04147
]
116671269 (erbb2)
04090 CD molecules [BR:
esp04090
]
116671269 (erbb2)
Enzymes [BR:
esp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
116671269 (erbb2)
Protein kinases [BR:
esp01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
116671269 (erbb2)
Exosome [BR:
esp04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
116671269 (erbb2)
CD molecules [BR:
esp04090
]
Proteins
116671269 (erbb2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
116671269
NCBI-ProteinID:
XP_032358292
LinkDB
All DBs
Position
21:complement(19830350..19851774)
Genome browser
AA seq
1292 aa
AA seq
DB search
MEAARSLVFLGAVLLVVTGTLGREVCLGTDMKLDLPSSLENHYETLRLLYTGCQVVHGNL
EITHLHGDPDLSFLQGIVEVQGYVLVAHVSVSLLPLDNLRIIRGSQLYNSSYALAVLDNT
LGGQGLRTLRLRSLTEILLGVVYIWGNPQLCFPDPQNIVWRDTLDEQNIHARLHKLQPRA
PKCPSCSSVCGKSCWGETAQDCQTLTRIKCASGCQRCKGPLPSDCCHLQCAAGCTGPKDS
DCLACRHFNDSGVCKENCPPPTIYDPSTYQTKPNPNKKFSFGATCVKTCPYNYLAMEVAC
TLVCPRTNQEVIVAHPDGNEMQKCERCEGDCPKVCYGLGMDNLGVMDNNGNIMVTSSNVE
QFNKCKKIFGSLAFLPQSFASDPVSNTSGLTLEQLSAFKRLEEITGYLYIDAWPEEWTNL
SVFENLKMIRGRMLYKGVFSLAIQNLHIRSLGLRSLRSVSGGLVLLHNNSQLCYTSSLPW
DSLLHPTQGPHRIVSKNQDAQLCEEEGRVCHPLCEGGCWGPGPSQCASCKAFQRGTECVE
QCDIYQGSIREYTDGSLCVACHSECRSLNGSASCHGPGAEHCSECQHFQDGEFCVDHCPS
GVKEDQQTVWKYSNATGHCLPCYTNCTLSCTVMDERGCPIDTRTGPGTTIAAAVGGVVLF
FILLALLVFYLRRQKKLRRKETMRRILQEHELVEPLTPSGASPNQAQMRILKETELKKLR
VLGAGAFGTVYKGVWAPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVASPYVCR
LLGICLTSTVQLVTQLMPYGCLLDYVRENKDRIGSQFLLNWCVQIAKGMSYLEEVRLVHR
DLAARNVLVKNPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILHRKFTHQSD
VWSYGVTVWELMTFGAKPYDMIPAREIPDVLEGGERLPQPLICTIDVYMIMVKCWMIDPE
SRPRFKDLVNDFSAMARDPPRYVVIQNDEQMSMSSPVDSQFFRMLLEEEGNNMRELLDAE
EYLVPQPNHFPRTQGDGASRHQSYRQSRDQGLDVEPSVAGGPRSMYSSLNTLGRSQYPTL
PLGVSTSNGVWVPQYPTLARSPSAGGQSDSVFLDGPPDELPPASPGRYCRDPTYSNGSQG
DLETDGPNGFYPSHHLNHSLPRRSHNHIMPEYVNQDIQDLRPGIPDRPSTLPRKGSRVDR
RLPNGLSSGHSVENPGYLVPVTVGAATSPAFDNPYYLDLVAKANAVARAAALDGPETLER
DGGVPRHVNGFLTSTAENPEYLGLADTWSGYT
NT seq
3879 nt
NT seq
+upstream
nt +downstream
nt
atggaggcggcgagaagtttggtgtttctcggggccgtgctgctcgtagtgacgggcacg
ttgggcagagaagtgtgcctgggtacagacatgaagctggacctgccctccagcctggaa
aatcactatgagaccctcaggctgctctacactggctgccaggttgtccacggcaacctg
gagatcacacatctgcatggagaccctgacctctccttccttcaggggatcgtggaggta
cagggctatgtactggttgctcatgtgtcagtgagtctgttgccgttggacaaccttcga
atcataagaggcagccagctatacaactccagctacgccctggctgtgctggataatact
ctgggcggacaggggctcaggacgctccggctccgtagcctcacagagatcctgttgggt
gtggtgtatatttggggcaacccccagctatgcttcccagacccccagaacattgtttgg
agggacactttggacgagcagaacatccacgcccggctgcacaaactgcagcctcgggct
cctaaatgtccaagttgttcctctgtatgtgggaaaagctgctggggagaaactgcacag
gactgccagaccttgacccgtattaaatgtgcgtctggctgtcagcggtgtaaaggtccc
ttacccagtgactgctgtcacctgcagtgcgctgctggatgcacaggacccaaagactca
gactgtctggcgtgccgccacttcaatgacagtggtgtgtgtaaggagaactgtcctcca
cctactatttacgacccctccacctatcagaccaaacccaacccaaacaagaagttcagc
tttggagccacctgcgtcaagacgtgtccttataactatctggctatggaagtggcttgt
actttggtttgtcccagaaccaaccaggaagttatcgtcgcccaccctgacggaaacgaa
atgcagaaatgtgaaaggtgcgaaggagactgtcccaaagtgtgttatggtctgggtatg
gacaacctcggcgtcatggacaacaatggcaacatcatggtaacatcttctaatgttgag
cagttcaacaagtgtaagaagatttttggtagtctggctttcctccctcagagctttgca
agcgaccctgtgagcaacacatcaggtctgaccctcgagcagctgagtgccttcaaaaga
ctggaggagattacaggttatttgtatattgatgcctggccagaagagtggactaacttg
agtgtgtttgagaacctgaagatgatcagaggcaggatgctctacaaaggtgttttttct
ctggccatccagaatttacacatccggtcgcttgggttgcgttcactacgcagcgtcagt
ggaggtttggtcctgttgcacaacaattcccagctttgctataccagttcactcccctgg
gatagtctcctccatcccacccagggaccccaccgcatcgtcagcaagaaccaggacgcc
caactctgtgaggaagagggccgtgtttgtcaccccctgtgtgaggggggctgctggggc
ccggggcccagccagtgtgcatcctgcaaggctttccaacgcggtactgagtgcgtggag
cagtgtgacatctatcaggggtctatccgtgaatacacagatggatctttgtgtgttgcc
tgtcactcagagtgtcgatctctcaatggctctgcctcctgtcatggcccgggtgcagag
cattgttcagagtgtcaacacttccaggatggtgagttttgtgtggatcattgtcccagc
ggtgtgaaggaggatcagcaaactgtgtggaagtacagcaacgctacaggacactgtctg
ccttgctacaccaactgcacgctgtcatgcactgtgatggatgagagaggctgccctatt
gacaccaggacaggaccgggtacaaccatcgcagctgcagtgggtggggtggtactcttc
tttatcctgctcgctctgctggtcttctacctgaggagacagaagaagctcaggaggaag
gagacaatgcggaggatcctacaagaacatgagctcgtggagcctttgacacccagtggc
gcgtcacccaatcaggctcagatgcgaattcttaaggagacggagttgaaaaaactcagg
gtgctgggtgcaggggcctttggtactgtttacaagggtgtgtgggctcctgatggggaa
aatgtgaaaataccagttgccatcaaggtgttacgagagaacacttcgccaaaggccaat
aaagagatccttgatgaggcctatgtgatggcaggagtggccagcccttacgtttgccgg
ctgctggggatttgtctgacctccacggtgcagctggtcactcagctgatgccgtacggc
tgcctccttgactacgtcagggagaacaaggaccgcatcggctcccagttcctcctcaac
tggtgtgtccagatcgccaaggggatgagttatctggaggaagtgcggctggtccacaga
gatttggccgcccgcaatgttctggtgaagaacccaaaccatgtaaagatcactgacttc
ggtctggcccgtctgctcgatatagacgagaccgaatatcacgctgatggagggaaggtg
cctattaaatggatggcactagagtctattctgcacaggaagttcactcatcagagtgat
gtctggagctacggtgtgacggtctgggagctgatgacatttggtgctaaaccatacgac
atgatcccagcgagagaaatcccagatgttttagagggaggagaacggcttccccagccc
ctcatctgcaccatcgacgtctacatgatcatggtcaaatgttggatgattgacccagaa
agcaggccgaggttcaaagatctggtgaatgattttagcgccatggccagagatccacct
cgctatgtagtcattcagaatgatgagcaaatgagcatgtccagcccagtggacagccag
tttttccgaatgcttctggaggaggaagggaacaacatgagggaactgctggatgctgag
gagtatctggtgcctcagccaaaccacttccccaggactcagggagatggggcatccaga
caccagtcatacaggcagagcagagatcagggcttagatgtagagccctctgtcgccggt
ggccctcggagcatgtactcctccctgaacactcttggccgcagccagtaccctacctta
cctttaggggtcagcacctccaatggcgtatgggtccctcagtacccaaccttggctcgc
agcccctcggccgggggccagtctgactctgtcttcctggatgggcctccagacgagctg
cccccagccagccccggacgttactgcagagaccccacctactcaaacgggagccagggt
gacctggagacagacgggccaaacggcttttatccttctcatcaccttaatcactcgctg
cccagacggagtcataatcatatcatgccagagtacgtcaaccaggatattcaagatctc
aggccggggatccccgatcggcccagcacgctgcctcgtaaaggctccagagtagaccga
cgcctccctaacggcctgagctccggtcacagcgtagaaaacccgggatacttggtcccc
gtaactgttggggctgccacctctccggcctttgacaacccatactacctggacctggtg
gccaaagccaatgctgtagccagggcagcagccttggacggccctgagacactcgagaga
gacggaggagtgcccaggcacgtgaacgggtttctgacctccacagcagagaatccagag
tatctgggactagcggacacctggagtggatatacttga
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