Etheostoma spectabile (orangethroat darter): 116694533
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Entry
116694533 CDS
T08457
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
esp
Etheostoma spectabile (orangethroat darter)
Brite
KEGG Orthology (KO) [BR:
esp00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
esp01001
]
116694533 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
esp04131
]
116694533 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
esp04147
]
116694533 (lrrk2)
Enzymes [BR:
esp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
116694533 (lrrk2)
Protein kinases [BR:
esp01001
]
Serine/threonine kinases: TKL group
LRRK family
116694533 (lrrk2)
Membrane trafficking [BR:
esp04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
116694533 (lrrk2)
Exosome [BR:
esp04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
116694533 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_4
LRR_8
Roc
COR
Ras
LRR_14
LRR_9
Arf
Ank_2
AAA_22
NACHT
LRR_13
AAA_16
PduV-EutP
Ank_3
Septin
nSTAND3
TFCD_C
Viral_helicase1
G-alpha
DLIC
ATP_bind_1
cobW
SRPRB
ABC_tran
Beta-prop_EML_2
T2SSE
GTP_EFTU
AAA_7
MMR_HSR1
NB-ARC
Pneumovirus_M2
DUF7079
MobB
UvrD-helicase
AAA_15
Motif
Other DBs
NCBI-GeneID:
116694533
NCBI-ProteinID:
XP_032380158
LinkDB
All DBs
Position
8:15779093..15820911
Genome browser
AA seq
2538 aa
AA seq
DB search
MFNTMVSNEELEERLKKLLVRLKILQEDRQLCTLIQIIEDLLFLAHTDNAAELFEDKDVH
VPLMVVLVSYISSKGVQQVGWSLLCRLIEICPDTLDQLTRPLQAGKDWDVLGVHQQILKV
LSEYRTDCRVTMVGLRALALLLRSDMIPLLLLEEEEDVFGLVVQAMKTFPNSEEVQLQGC
RALQFLLERVSDDHLVEFVENQDHVVVLAALQMFPDSPELHLEAMKVLLPLARPGSNVEM
LMSGGARCYSVVVAAMDTFSEVEELQETACCLFRRFTSESYYNILVLNGVLRVLVRACQT
FPDNVKLQAAALSCLADLTPTIVQNKAVAEQGLEEGEEEENRGREEVDDMGLGWMEVCCT
ALELHAAEPDVQEAASWAIHNLLLHGVKHSEEEQEERTPVHRQLMAAMLLHSSSPSVFQA
ATSAIATLLTHNSKMRSLLLSSGLHVNLVEMMKRHSTSAEVSVSACKLLSLLFQGRTASL
DELNMAMSQILSSMKVHNFQPEVQLEALQASLVFLCPERSLREHGVSVADPDMADVSLKV
LKNQCVVEGAHTLYLEVLNRFISSSTIQTCGLKVLSALADCSGAVDLLCQQGAIDTVLHT
LQMFPQEREIHYWGLTLLNYLVTKKKLSRMIVPVLASVVVASLIQYREESEMLLKCFQVA
LRMLDACSGAAAELQREDFDRQIFKHLRETSDQNNNALRKSVCLALSKMWCDSQLHYNML
EKACEDGDTTLAECLIELGADINGKTKTESLIYQVCERGGPLELVELLLSRGAHEQHLRR
ALAVSVKRGEGPTVIQLLGRLGLDLNNSALCLGGFRLGRLDAAWLSPLLTERGRTYSLRY
KNSKGMSLARYIQSLQRSKSLGGPPRSLGGDPCLTSGYISDESDDSSFSFVSMEDSLFDD
LESDGKSDSLPGVLSPKPHNNSTEELRDGSFRRKQGRRRHASAESGPTEKEHSEHVHRRY
GRTGSSQKVFGFAESSVALPKEKERIRLLDLSGNELDSLSCLMDDGFVQQQLGHLLRLDL
SHNRLLEFPSALCQSLKSLTRLDLQGNQLQSLPVELLSLLSLSMLNVSRNCVGPLLTFDP
AVTCRSLRQLNLSFNKITTFPHELGRAMSQLEELFMEGNSITELCVPLILPEIKLLDVSK
NSVENISPDFLTACPKLETFSASMNKICSLSYLPSRITTLKLANNSFTCVPEAILNLPNL
RSVDMRTNSIADLPGPGLWESSNLRELMFSHNCIKVLDLSGPTYKWTRLEKLHLSDNKLT
EIPPQIGLLEDLTSLDVSRNTNLRSFPDEMGKLGRLWDLPLDGLRLQLDLKLIGTKTKDI
VRFLQQRLKKAVPYYRMKLIVVGNAGSGKTTLIQQLMKLKRSQLNSKQDAVGIDVRDWTI
RERDKKKMVLNVWDFSGGEEFSGSHPHFLTSRALYLVVYNISKGASQVDALKPWLFNIKA
VAPLSPVILVGTHTDVSDELQLQACLTKIREELLNHQGFPAIRDYHMVSVCEDSDAMAKL
RKAIAREVSSFKIQGQPVMGQLVPDSYVELERRVLQERTRVPPEFPVLRHQELLQLIQES
QLQLEEAELSHAVHFLSEAGLLLHFDDPALQLQELYFIDPQWLCNIISQKLTLKSGGFWE
HPKGVVQRSVVEKFLFETKCFPKSHMTQFFKLLEKFQIALPFGEDQLLIPSSLSKHRPVI
ELPHCENSEVIVRLYEMPYFPMDYWSRQISRLLEVSSYLLCGGGKAVRPNRIYWRRGVYL
SWSPEAYCLVEENPSSFVRITVPSSRKGRVLLGQVVDHIDSLLEEWFPGLLNTDVHGSGE
ALLKKWALYSFEDGQEWSKILLEDLFTYFDNDFLLVNPKDPRYTLPISQIAPDLVLSDQP
AGTILDSEELDVDMSKENQLGDGGYGTVYRGVYKNEEVAVKIFNKHASELYIYRLLRQEL
AVLGRLRHPSLVGLLAAGSVPQVLVMELALRGSLDSLFEHENGSLNLKLQHRIALHVADG
LRYLHAAMIIYRDLKPHNVLLFNLKTDSEIIAKITDYGIAQYCCSMGVRSSEGTPGFRAP
EVARGSVIYNQQADVFSFGLLLYDLLTCGERISDGMKFPSEFDEVAVQGKLPDPVKHYGC
SPWPGFQTLMKDCLRESPQGRPTSAQVFDRLNSGEMLCLMRELVVPRVFNAECFTVSSGS
RDGPSNRHRAWLGGGSSTQRLGSITAVDLDTSTVTTQEIDNSPVLCLVTVQIPTESCDWL
VAGTQSGSLVLISTQDTSIWHHLQSVTDAVTSLYFHVHPHRTQRKNYLLVGTADGVLTVF
EDSVLKQENGQPVKTLTVGNVNTPVMCLGQSVHSLDSRSVWAGCGTKILSFTADYDVGKS
IDTRPSLVFQQARSLGGEACVSRMVVDKYVYLSKAGTPTVEVWDKRSERMVDCIDCAQII
RHDSGCRGRQGSEVGLPADAAPSWARVKALLVQSSATLWIGTRGGHLLLLELSKHQPLQV
IGPVCSSIRCIASALIETLNWKNVVLILARRQDRNDFGEESVLMVWNGALPMEGKDLNKH
CEKREQIAAKMREQLQHA
NT seq
7617 nt
NT seq
+upstream
nt +downstream
nt
atgtttaacaccatggttagcaacgaggagttagaagaaaggttgaagaaacttctggtg
aggctgaaaatcctgcaagaagacagacaactgtgcacactaatacaaataattgaggac
ctgcttttcctggcgcacaccgacaatgcagctgagttgtttgaagacaaagatgtccat
gtccccctcatggtggtgctggtgtcctacatcagcagcaaaggagtccagcaggtgggt
tggtcattactgtgtcgtctaattgaaatatgccccgatacgctggaccagctgaccaga
cctctgcaggcaggcaaggactgggatgtactgggagtgcaccagcagatcctgaaagta
ctatcagagtacaggacagactgcagagtgaccatggttggactccgagccctggctctc
ctgctcagatcagacatgattcctttgctgctgctggaggaggaagaggatgtgtttggc
ttggtggtgcaggcaatgaagacgtttcctaacagtgaagaggtgcagcttcaaggctgt
agagctctgcaattcctcctggagagagtaagtgatgaccacctggtggagtttgtggag
aaccaggatcatgtagtggttctggcggctctccaaatgttcccggacagccccgagctg
cacctggaggccatgaaggtgctgctcccactggctcgtcctggcagtaacgtggagatg
ttgatgtcgggaggcgctcggtgctacagcgtggttgtcgccgccatggacacgttctcc
gaggtggaggagttgcaggagacggcctgctgcctgttcaggaggtttacatcagagagt
tactacaacatcctggtactgaacggcgtcctgagggtcttggtcagagcctgtcagact
ttccctgacaacgtcaagctgcaagctgccgctctctcctgtctggctgacctcacccca
accatcgtgcagaacaaagcggtggccgagcagggtctggaggaaggggaggaggaggag
aaccggggtagggaggaggtggacgacatgggcctgggctggatggaggtctgttgtacg
gcactggagctccacgctgccgagccagatgttcaagaagctgcgagctgggccattcac
aatctgttactgcacggagtgaagcattcagaagaggaacaggaagagaggactcctgtc
cacagacagttgatggcggccatgctgctccactcctcctcccccagcgtgtttcaagct
gctaccagtgccatcgccacactcctcacacacaacagtaaaatgcgctcgctgctgctg
tccagtggcctccacgtcaacctagtggagatgatgaagagacattcaacctcagctgaa
gtttcagtcagcgcctgtaaactgctcagcctgctcttccagggaaggaccgccagtcta
gatgagttgaacatggccatgagtcagatcctcagcagcatgaaggtccacaacttccag
ccagaggtccagctggaggctctgcaggccagcctggtcttcctctgcccggaaaggagt
ttaagggagcacggcgtctctgtcgcagatcctgacatggccgacgtgtcactgaaggtg
ctgaaaaaccagtgtgtggtggaaggagctcacaccctctacctggaggttctcaacagg
ttcatcagcagctcgaccatacagacgtgcggtttgaaggtgctgtctgctctggctgac
tgctctggtgcagtggacctgctctgccagcagggggcgatagacacagtgctgcacaca
ctacagatgttcccacaggaacgagagatacactactggggtctcaccctgctcaactac
ctcgtaaccaagaagaagctgtcgaggatgatcgtacctgttctggcctccgttgtggtc
gcctcactcatccagtacagggaagagtctgagatgctcctgaagtgttttcaggtggct
ctaaggatgctggacgcttgttcaggagcagctgctgaactgcagagagaagactttgac
aggcagatcttcaaacacctcagagagacttctgaccagaacaacaatgctctgcgtaaa
tcggtgtgcctggctctgtctaagatgtggtgcgactcacagctacactacaacatgctg
gaaaaagcctgcgaggacggagacacgacattggctgagtgtctgatcgagctgggcgca
gacatcaatgggaaaaccaaaacagaatctctcatctaccaggtgtgtgagagaggcggc
cctctggagctggtggagctcctgctcagccgaggtgcccacgagcagcacctccgcagg
gctctggctgtgagcgtgaagcggggcgaaggacctacagtcattcagctgctgggccgt
ctgggtctggacctcaacaacagcgccctctgcctcgggggcttcaggctgggccgcctg
gacgccgcctggcttagcccgctgctgacggaaagaggcagaacatacagtctccgttac
aagaacagtaaaggtatgagtttggcgaggtatattcagtctctccagaggtccaagagt
ctcggtggtcctcctagatctctgggcggcgacccgtgtctcacatctggctacatttct
gacgaaagcgacgactccagcttcagctttgtctccatggaagacagtttatttgacgat
ttggagagtgacggtaaaagtgattccctgcctggtgtactgtctccaaagccacataat
aattcaacagaagagttgagagacgggtctttcagaaggaagcagggacgccgcagacat
gccagtgcagagagtggtccaactgagaaggaacacagcgagcatgtacacaggagatac
ggaaggactggctcaagtcaaaaagtgtttggatttgctgagagctctgttgctctgccc
aaagagaaggaaaggatccgccttctggacctgtcggggaacgaattggactccctgtcc
tgtctgatggatgatggcttcgtccagcagcagctggggcatctcctccgtctggacctg
agccacaacagactgctggagtttccctcagctctttgccagagtttgaagagtctgact
cggttggacctgcagggcaaccagctccagtcgctgccagtggagctgttgtctctgctc
tcactgagcatgctgaacgtctcacgtaactgtgtgggtcccctactgacctttgaccct
gctgtcacctgccgatcactgcggcagctcaatctttctttcaacaaaatcaccacgttc
cctcacgagctgggccgtgccatgagtcaactggaggagctgttcatggaaggcaacagt
ataactgagctttgtgtgcctctgattctgcccgagatcaagctgctcgatgtgagcaag
aacagcgtggagaatatttctccagacttcctgactgcctgccccaaactagaaactttc
agtgcctccatgaacaaaatctgttccctgtcatatctcccatccaggatcaccacactg
aaactagcaaacaacagctttacttgtgttcctgaggcgatccttaatctcccaaacttg
cggtcagtggacatgagaaccaacagcatcgctgatctgcctggcccgggactctgggag
tccagcaacctcagagagctgatgttcagtcacaactgtatcaaagttctggatctgagt
gggccgacctacaaatggaccagactggagaaactccacctgagtgacaacaagctcaca
gagatccctccacagatcggcctgttggaagatctgacctccttggatgtgagtcgtaac
accaacctgcggtccttccctgatgagatggggaaactgggcagactgtgggacctgccg
ctggacggccttcgcctccagctggacctcaaactcattggcaccaagaccaaggacata
gtcaggttcctgcagcagcggctgaagaaggcagtgccgtactaccggatgaagctcatc
gtggtggggaatgctggcagcgggaagaccaccctgatccagcagctgatgaagctgaag
cgctcccagttgaactcgaagcaggatgcagttggcatcgacgtgcgggactggaccatc
agggagcgggacaagaagaaaatggtgctgaacgtctgggacttctcaggtggagaggag
ttcagtggttcccaccctcacttcctgacttccagagctctctacctggtggtgtacaac
atcagcaaaggagccagtcaggtggacgcactcaagccatggctcttcaacatcaaagcc
gtagcccctctgtccccggtcatcctggtgggaacccacacagatgtgagtgatgagcta
caacttcaggcctgcctgaccaagatcagagaggagctgctgaaccaccagggcttccct
gccatccgggactaccacatggtctctgtctgcgaagactcggacgccatggccaagctg
cgcaaggctatcgccagggaagtcagcagcttcaagatccagggccagcctgtgatgggc
cagttggttccagacagctacgtggagctggagcgccgggttctgcaggagagaaccagg
gtccccccagagttccccgttctcaggcaccaggagctgctgcagctcatccaggagagt
cagctgcagctggaggaagctgagctgtcccacgctgtccacttcctgagtgaagccggg
cttttactgcactttgatgatcctgcacttcagcttcaagagctctacttcatcgaccca
cagtggctgtgcaacatcatctcccagaagctgacattaaagagcggtggcttctgggag
catcctaaaggagttgttcagcgctcagtggtggaaaagtttctgtttgagaccaaatgt
tttcccaagagccacatgacgcagttcttcaaattgctggagaagtttcagatcgctcta
ccctttggcgaggaccagctactgatacccagcagtttgtccaaacacagaccggtgata
gagctgcctcactgtgagaactcagaggtgattgtgcgtctgtacgagatgccgtacttc
cccatggattactggtctcgccagatcagcagactactggaggtctcttcttatctgctt
tgtggaggaggaaaagcggtgcgaccgaaccggatctactggaggagaggcgtgtacctg
agctggtccccagaggcctactgtctggtggaggagaacccctccagcttcgtcaggata
actgtgccctcttcacgcaaaggccgggtgctgctgggtcaggtggtggatcacatcgac
tccctgctggaggaatggtttcctggcctgctgaacactgatgtgcacggcagtggtgag
gctcttctgaaaaagtgggctctctacagctttgaggacgggcaggagtggagcaagatt
ctgctcgaggacctcttcacatattttgacaatgattttctgttggtgaacccgaaggat
ccccgctacacactccccatctctcagatcgcccctgacttggtactgagtgaccagcct
gcagggacaatactggacagtgaagagctggatgtagacatgtctaaagagaaccaactg
ggggacggtggctatgggactgtctatcgaggtgtctacaaaaatgaagaagtagccgtg
aaaatattcaacaagcatgcatctgagctttacatctacagactcctcagacaggagttg
gcggtgttgggtcgcctccgtcaccccagcctggtgggtctgctggcagccggctcagtt
cctcaggtcctggtgatggagctggcactgcgcggctcactggactccctctttgaacat
gagaacggcagcctgaacctaaagctccagcacagaatcgccttgcatgttgccgacgga
ctcaggtaccttcacgctgccatgatcatatatcgagatctcaagccccacaacgttctc
ctgttcaacctgaagaccgattccgagatcatcgccaagattaccgactatggcatcgct
cagtactgctgcagcatgggcgtaaggagctcagagggcacgccaggtttccgagcacca
gaggttgcccgaggcagcgtgatctataaccagcaggctgatgtgttctcattcggcctg
ctgctctacgacctcctgacctgtggtgagcgcatctctgacggcatgaagttccccagt
gagtttgatgaggttgcagtgcaggggaaactgccagatccagtgaaacactacggttgc
tcaccgtggccgggcttccagacgctgatgaaggactgtttgagggaaagccctcagggt
cgacccacttctgctcaggtgtttgataggctgaattcaggggagatgttgtgcctgatg
agggagctggtggttccccgggtgttcaacgctgagtgcttcacagtgagctccggcagc
agggacggcccctccaaccggcacagagcctggctggggggaggcagcagcacgcagagg
cttggctccatcacggccgtagacctggacaccagtacagtcactacacaggagatcgac
aacagtcccgttttgtgtcttgtgaccgtccaaatcccaaccgagtcctgtgattggctg
gtggcaggcacccaatccggctctttagtgctcatcagcactcaggacacgtcgatttgg
caccacctgcagagtgtcacagacgccgtcacctcactgtacttccatgtacaccctcac
cgcacccaaaggaagaattacttgctggttgggacagcggatggagttctcactgttttt
gaggactctgtactcaagcaagaaaacgggcagccggttaaaaccctcactgtgggaaac
gtcaacacgcctgtcatgtgtctgggccagtcggtgcattcgctggacagcaggtcggtg
tgggccggctgcgggaccaagatcctctccttcaccgccgactacgacgtcggcaagagc
atcgacacgagacccagcctcgtcttccagcaggcgcggtcattgggaggtgaagcgtgt
gtgtctcgaatggttgtggataaatatgtttacctgagcaaagccgggacaccaaccgtc
gaggtttgggataagagaagtgagaggatggtggactgcatcgactgtgctcagatcatc
agacatgactcgggctgcagaggcaggcagggcagcgaggtggggctgcccgctgacgca
gctccctcctgggccagagtcaaagccctgctggtgcagagctcagcaactctctggatc
ggcactagagggggccacctgctgctgctggagctctccaaacaccagccgctgcaggtc
atcggccctgtctgcagttccatccgctgcatcgcctctgccctcatagaaacactaaac
tggaagaatgtggtgctgattttggccagaagacaagacaggaatgactttggcgaggag
tcggtgctgatggtgtggaacggcgcgctgccgatggagggcaaagacctgaacaaacac
tgcgagaaaagagagcagatcgcagccaaaatgagagagcagctccaacatgcctga
DBGET
integrated database retrieval system
