Etheostoma spectabile (orangethroat darter): 116703721
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Entry
116703721 CDS
T08457
Symbol
tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
esp
Etheostoma spectabile (orangethroat darter)
Pathway
esp04217
Necroptosis
esp04620
Toll-like receptor signaling pathway
esp04621
NOD-like receptor signaling pathway
esp05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
esp00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
116703721 (tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
116703721 (tyk2)
04621 NOD-like receptor signaling pathway
116703721 (tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
116703721 (tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
esp01001
]
116703721 (tyk2)
Enzymes [BR:
esp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
116703721 (tyk2)
Protein kinases [BR:
esp01001
]
Non-receptor tyrosine kinases
JAK family [OT]
116703721 (tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
Jak1_Phl
SH2_1
Kdo
Kinase-like
ABC1
SH2
Motif
Other DBs
NCBI-GeneID:
116703721
NCBI-ProteinID:
XP_032394542
LinkDB
All DBs
Position
15:11926477..11938080
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AA seq
1168 aa
AA seq
DB search
MSRSRWSRRSKPGALPGLCEPPKGQGIHVYLFWSKEGERYLSYTSGRVTAEELCISAAEA
VGITPLCHVLFALYNPQSRCWYSPNHEFSPENTSLVLHYCMRFYFRNWHGLNEKEPTVSR
YALRSGTSQGGYPLLDLTSLEYLFSQAKYEFVNEVVQMEDIESEEEISRFKNESLGMAVL
QLSHQAMQTDCTLQDVAEKVSYMHCIPRSFAKLISKDNFLTKIRIRRVFAEFVRTFQQHT
VDKGRLGTHEIMYKYISTLEHLAPRFGTETFPVSHLELRKDGDGSSSYSNTTHAQGASKD
DFSLPATHEIMVSGTKGIQWRKVSGQKAQANTYLRNDYMNYMKKTKQQSSQPNADTPNKW
TSFCDFPEITHIAITGDNVCISTQDNHCMEVQMNSSQQARSFISLLDGYNRLTAFAHHYL
CHDVAPPRVVLSLANGLHGPIHDDFVLLKLKKEAAEEGAFLVRWSALDYRRIILAVLNKN
ENGSKPSHKQFRIQLKGSMFCLEGWDREFSSVKELTESLKTFVLKSGSDSFTVKKCCLPK
QAELSNLLVIRQGVHIDSLSLNMTQLRFHQIKDKEIKQGQHLGRGTRTNIYSGRLLVRGG
GENDEDEECNNNFADRNGIHVVLKILEQSDKDIDIGFLETASLMSQVSHSHLVFVHGVSV
KGSENIIVEEFVEFGPLDVFLRKEKASVTPQWKFIVAKQLASALNYLETKRLVHGNVCAK
NILVARRGLEHGTTPFVKLSDPGIALNVLSREERLERIPWIAPECVDSGVPVFNASDQWS
FGITLLEICNNGDLPMSGSTLSEKERFYQQKGRLAEPSSQELASFISMCLTYETVERPSF
RTVLRELTEIMIKNPDISPSETLPDTDPSVFHKRYLKKMRDLGEGHFGKVTLYLYDPAND
GTGELVAVKALKQDNGHVPEGWIKEIEILKSLYHSNIVKYKGCCTELGGQVVQLIMEYLP
LGSLQKYLPTHKLGMSRCLMFAQQICQGMEYLHSKRYIHRDLAARNVLVENESLVKIGDF
GLTKYIPEGEIYYRVREDGDSPVFWYAIECLKESKFSFSSDIWSFGVTLYEILTRCDHRQ
SPPVKFVEMMDRPQGQMTVMVLIKQLEKQQRLPRPKDCPQEMKMLMEQCWAADPAQRPSF
KSLIEKFEAIRQTYDWQSHINFSSAQIC
NT seq
3507 nt
NT seq
+upstream
nt +downstream
nt
atgtccaggagtcggtggtccaggcgttcaaagccaggagcactcccgggcctgtgtgag
ccccccaagggtcaaggcatccatgtttacctattctggtcaaaggaaggggaaagatat
ttgtcttacacaagtggaagagtcacagcagaggagctgtgcatctcagctgcagaggct
gtagggataactcctctgtgccatgtgttgtttgctctgtacaatccacaatcacgttgc
tggtacagtccaaaccatgagttcagtccagagaacaccagtcttgtacttcactactgt
atgaggttttacttccggaattggcacggacttaatgagaaggagccaactgtatcccgt
tatgctttaagatctgggacaagtcagggtggttaccctcttcttgacttgacatccttg
gaatacttattctcccaggcaaaatatgaatttgtaaacgaagtagtacagatggaagac
attgagtcagaggaggagataagccgcttcaaaaatgagagcttggggatggctgtgctt
caactctcacaccaggcaatgcaaacagactgtaccttacaagatgttgcagaaaaagtc
agctacatgcactgcattccaaggtctttcgccaaactcatttccaaagacaacttcctg
acaaaaatccggatccggcgggtgtttgcagagtttgtgcggaccttccagcagcacact
gttgataaggggcgactaggcacccacgagataatgtataagtacatctctactcttgaa
cacttggcaccacgttttggaacagagaccttccctgtatcccacctggaactgagaaag
gatggggacggaagcagctcttactctaacaccacccatgcgcagggtgcctcgaaagac
gacttcagtcttcccgccacacatgagataatggtgtctggcaccaaggggattcaatgg
aggaaggtgtccggtcaaaaggcgcaggcaaacacttacttaagaaatgactacatgaac
tacatgaagaaaacaaaacaacagtccagccaaccaaatgcggacactcccaataaatgg
acctccttctgtgatttccctgaaataactcacatagccatcactggagataatgtgtgc
attagcactcaggacaaccactgcatggaggttcagatgaactccagccagcaggcccgt
tccttcatctccctccttgatggatacaaccggctgactgcattcgcccaccactatctt
tgtcatgatgtggctcccccaagggtagtgctgagtttggcaaatggactgcatggacct
atccatgatgattttgtgctgctgaagctgaaaaaggaggcagcagaggagggagctttc
cttgtacgttggagtgctcttgactatcgccgcatcatcctagctgtcctgaacaaaaat
gagaacggatcgaagccaagccataagcagtttcggattcagctcaagggttccatgttc
tgtctggagggatgggatcgagaattctccagtgtgaaggagctcacagaaagcctcaag
acctttgtactcaagtctggttcggacagctttactgtcaaaaaatgctgtttgccaaaa
caagcagagctatccaaccttctggtgataaggcaaggtgttcatattgactccttgtcc
ctgaacatgacccagctacgcttccaccagatcaaggacaaagagatcaaacagggacag
catttgggccgtgggaccagaactaacatctactcaggacgtctgctggtgcgaggtgga
ggagaaaacgacgaagacgaagagtgcaacaacaactttgctgaccgcaacgggatccac
gtggttctcaagattctagagcaaagcgataaagatattgatataggctttttggaaaca
gcaagtctcatgagccaggtatcccacagccacctggtgtttgtacatggtgtgtcagtc
aaaggatctgaaaacatcatagtggaagaatttgtggagtttgggcctttggatgttttc
cttcgcaaagaaaaggcatctgtgactcctcagtggaaatttattgttgcaaaacaactt
gccagtgccctcaattatcttgagaccaaacggctggttcatggaaacgtctgtgccaag
aacattctggtggcaaggcgtggtctggagcatggcactactccttttgtcaagctgagt
gacccaggaattgccctgaatgtcctttcacgggaagagcgtcttgagcgcatcccatgg
attgcccctgagtgtgttgacagcggcgtacccgtttttaatgcttctgaccagtggagc
tttggcatcacgctgctcgaaatctgcaacaatggcgatcttccaatgagtggcagcaca
ttgtctgagaaagagcgcttttatcagcaaaagggtcgtttagctgaaccgtcctcccag
gaactggccagctttatcagcatgtgtttgacctacgagactgtggagaggccttccttc
cgcactgtgctcagagagctcacagaaatcatgattaaaaatcctgatatatctcctagt
gaaactctccctgatacagaccctagcgtgttccataaacgctacctgaaaaaaatgcgg
gatttaggagagggtcactttggaaaagtcactctctacttgtatgacccggccaacgat
ggtacaggagagcttgtggcagtgaaggctttgaaacaggacaacggtcatgtgcctgag
ggctggatcaaggagattgagatcctcaagtccctttatcacagcaacattgtcaagtac
aagggctgttgcactgaactgggaggacaagtggtgcagctgataatggagtaccttcct
ctggggagtctgcaaaagtaccttcccacacataaactgggaatgtcccgatgccttatg
tttgctcagcagatctgtcagggtatggagtacttgcactctaaacgatatatccatcga
gaccttgctgcccgtaatgtcttagtggaaaatgaaagtttggtgaagattggagacttt
ggcctgacaaagtacatcccagagggcgagatctactaccgtgtccgtgaggatggggac
agtccagtgttttggtatgccattgagtgcttgaaggaaagtaaattttccttttcctct
gacatttggtcgtttggcgttacgttgtacgagatcctgacccgctgtgaccatcgccaa
agccctccagtaaagttcgtggagatgatggacagaccccagggacagatgactgtgatg
gttctcataaaacagttggagaaacaacagcgattgcctcgtcccaaagactgcccgcaa
gagatgaagatgttaatggagcagtgttgggctgcagaccctgcacaacgaccatcgttc
aaatcccttattgaaaagtttgaggctattcgccaaacatacgactggcagtcgcatata
aacttttcctcggctcagatttgctga
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