Eubacterium siraeum V10Sc8a: ES1_19950
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Entry
ES1_19950 CDS
T02589
Name
(GenBank) Isopropylmalate/homocitrate/citramalate synthases
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
esr
Eubacterium siraeum V10Sc8a
Pathway
esr00290
Valine, leucine and isoleucine biosynthesis
esr00620
Pyruvate metabolism
esr01100
Metabolic pathways
esr01110
Biosynthesis of secondary metabolites
esr01210
2-Oxocarboxylic acid metabolism
esr01230
Biosynthesis of amino acids
Brite
KEGG Orthology (KO) [BR:
esr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
ES1_19950
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ES1_19950
Enzymes [BR:
esr01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
ES1_19950
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
CBL34876
UniProt:
D4MM93
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All DBs
Position
complement(2150815..2152491)
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AA seq
558 aa
AA seq
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MKGTMNTNKYSRGYFMPPVQCLDWTKKEYIDKAPIWCSVDLRDGNQALIVPMNLEEKLEF
FKVLVAIGFKEIEIGFPAASETEYEFCRALIEQDLIPDDVTIQVLTQSREHIIKKTFEAL
AGAKHAVVHLYNSTSVAQREQVFRKPKNEIIDIAVEGAKLLKEYREKTPGDFKFEYSPES
FTGTEPEFALEICNAVLDVWQPTPDDKVIINLPVTVEMSLPHVYASQVEYMCKNMVNREN
VIVSLHPHNDRGCAVADSELGLLAGADRIEGTLFGNGERTGNVDIVTLALNMYSHGVDPK
LDFSDLPSITEVYEKMTCMKVYDRQPYSGSLVFAAFSGSHQDAIAKGMKWREEKDPEHWT
VPYLPIDPMDIGRQYDGDVIRINSQSGKGGIGYLLQQKYGVDLPKKFREKVGYTVKSVSD
HQHKELTPDEVYEVFRSNFVNKETALKITEAHYKQENGGIAATVTAEYKGSTAVYTGSGN
GRLDAVSDAIKNGLGLSYSLVTYNEHAIEVGSKSKAAAYVEICDKNGNSFWGAGIHTDII
NSSVSALVSAINNSDMVK
NT seq
1677 nt
NT seq
+upstream
nt +downstream
nt
atgaaaggtacaatgaacacaaacaaatactccagaggatatttcatgcctcccgtacag
tgtcttgattggacaaaaaaggagtacatagataaggctcctatatggtgcagtgtcgat
ctgcgtgacggaaatcaggcgcttatagttcctatgaatcttgaagaaaagcttgaattc
ttcaaggtgcttgtagcgataggcttcaaggagatcgagataggtttccccgcagcgtcc
gaaacggaatatgaattctgccgtgcattgatagaacaggaccttatccccgatgacgtt
actattcaggtacttacacagtcaagagaacacatcataaagaaaacgtttgaagcactt
gcaggtgcaaagcacgcagttgtacatctgtataattccacctctgttgcacaaagagaa
caggtattcagaaagcccaagaacgagattattgacatagccgttgaaggagcaaagctg
ctcaaggaatacagagaaaagacacccggcgacttcaagtttgagtattcgcccgagagc
tttaccggaacagagcctgaatttgcacttgagatatgcaatgcggtgcttgacgtatgg
cagcccacccccgatgataaggttataatcaatctgcccgttaccgtagaaatgtcgctt
ccgcacgtttacgcaagtcaggtagagtatatgtgcaagaatatggtgaacagagagaac
gttatcgtttcgcttcatccccataatgacagaggctgtgccgttgcagacagcgagctt
ggcttgcttgccggcgctgacagaatagagggtactctgttcggaaacggtgagcgtacc
ggtaacgttgacatagtaacgcttgctcttaatatgtactcgcacggcgtagatccgaag
ctcgacttctccgacctgccctcgataacagaggtttacgagaagatgacctgtatgaag
gtctacgacagacagccctacagcggctctctcgtgtttgcggcattctcaggctcacat
caggacgctatcgcaaagggtatgaagtggcgtgaggaaaaggaccctgagcattggaca
gttccttatctgcccatagaccctatggatataggcagacagtatgacggtgacgttatc
cgtatcaacagccagagcggaaagggcggtatcggttatctgttacagcagaagtacggt
gtagacctgcctaagaagttccgtgaaaaagtcggctatacggttaaatccgtttccgac
catcagcataaggagcttactcccgatgaagtgtatgaagtattccgcagtaattttgtg
aataaggaaaccgcactgaaaatcaccgaggcacactataagcaggaaaacggcgggatc
gcagctaccgttacagccgagtacaagggcagtacggcagtgtataccggcagcggcaac
ggcagacttgacgcagtgagcgacgctataaagaacggtcttggacttagctacagctta
gtaacatataatgaacacgctatagaggtaggctcaaagtcaaaggcggcggcttatgtt
gagatatgcgacaagaacggaaactcgttctggggcgcaggcatccataccgacatcatc
aacagctccgtcagcgcacttgtttccgctatcaataacagcgatatggtaaagtaa
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