KEGG   Escherichia sp. E4742: FEM44_01755
Entry
FEM44_01755       CDS       T06276                                 
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
  KO
K11754  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
Organism
esz  Escherichia sp. E4742
Pathway
esz00790  Folate biosynthesis
esz01100  Metabolic pathways
esz01240  Biosynthesis of cofactors
Module
esz_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:esz00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    FEM44_01755 (folC)
Enzymes [BR:esz01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.12  dihydrofolate synthase
     FEM44_01755 (folC)
    6.3.2.17  tetrahydrofolate synthase
     FEM44_01755 (folC)
SSDB
Motif
Pfam: Mur_ligase_C Mur_ligase_M
Other DBs
NCBI-ProteinID: QCT86047
LinkDB
Position
complement(363874..365142)
AA seq 422 aa
MIIKRTPQAASPLASWLSYLENLHSKTIDLGLDRVSLVAARLGVLKPAPFVFTVAGTNGK
GTTCRTLESILMAAGYRVGVYSSPHLVRYTERVRIQGKELAESAHTASFAEIEAERGDIS
LTYFEYGTLSALWLFKEAQLDVVILEVGLGGRLDATNIVDADVAVVTSIALDHTDWLGPD
RESIGREKAGIFRSEKPAIVGEPEMPYTIADVAQEKGALLQRCGVEWNYSVTDHDWSFTD
AHGTLAGLPLPLVPQPNAATALAALRASGLEVSEKAIRDGIASAILPGRFQIVSETPRVI
FDVAHNPHAAEYLTGRMKALPKNGRVLAVIGMLHDKDIAGTLAWLKSVVDDWYCAPLEGP
RGATAARLLEHLGNGKPFDSVAQAWEAAMADAKPEDTVLVCGSFHTVAHVMEVIDARRSG
GE
NT seq 1269 nt   +upstreamnt  +downstreamnt
atgattatcaaacgcactcctcaagccgcgtcgcctctggcttcgtggctttcttatctg
gaaaacctgcacagtaaaactatcgatctcggccttgatcgcgtcagcctggttgcggcg
cgtcttggcgtccttaaacctgcaccgtttgtgtttaccgttgcgggaactaatggcaaa
ggcacgacctgccgtacgctggagtcgattctgatggcggcagggtacagggtgggggtc
tacagttcgccgcatctggtgcgttataccgagcgcgttcgtatacagggcaaagaactg
gcggagtcggcccatacggcttcttttgccgagattgaggccgagcgcggcgatatttct
ctgacttattttgaatacggtacgctgtcggcattgtggttgttcaaagaggcgcaactc
gatgtggtgattctggaagtaggtctgggcggtcgtctggatgcgactaacattgtcgat
gctgatgttgccgtggtgaccagtattgcgctggatcataccgactggctggggccagat
cgtgaaagcattggtcgtgagaaagcggggatcttccgcagtgaaaaaccggcgatcgtc
ggtgaaccggaaatgccttacaccattgccgatgtagcacaggagaaaggcgcactgttg
caacgttgtggcgttgagtggaattattcagtcactgaccatgactggtcatttaccgac
gctcacggcacgctggcggggttaccgttgccacttgtcccgcaaccgaatgccgcaaca
gcgctggcggcactgcgtgccagcggcctggaagtcagtgaaaaggcaattcgcgacggt
attgccagcgcaattttgcctggacgtttccagattgtgagcgagacgccacgcgttatt
tttgatgtcgcccataatcctcatgcggcggaatatcttaccggacgcatgaaagcgtta
ccgaaaaacgggcgcgtgctggcggttatcggtatgctacatgataaagatattgccgga
acactggcctggttgaaaagcgtggttgatgactggtattgtgcgccactggaagggccg
cgcggtgccacggcagcacgattgcttgagcatctggggaacggcaaaccattcgatagc
gttgcgcaggcatgggaagccgcaatggcggacgctaaaccggaagataccgtgctggtg
tgtggttcgttccatacggtcgcacatgtcatggaagtgattgacgcgaggagaagcggt
ggcgagtaa

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